Detailed information    

insolico Bioinformatically predicted

Overview

Name   sepM   Type   Regulator
Locus tag   ETT54_RS05990 Genome accession   NZ_CP035445
Coordinates   1174802..1175839 (-) Length   345 a.a.
NCBI ID   WP_136098239.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain emm92     
Function   processing of CSP (predicted from homology)   
Competence regulation

Genomic Context

Location: 1169802..1180839
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ETT54_RS05970 (ETT54_05965) - 1170553..1171179 (+) 627 WP_010922497.1 A24 family peptidase -
  ETT54_RS05975 (ETT54_05970) rlmN 1171261..1172340 (-) 1080 WP_002992788.1 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN -
  ETT54_RS05980 (ETT54_05975) - 1172344..1172964 (-) 621 WP_011285637.1 YutD family protein -
  ETT54_RS05985 (ETT54_05980) - 1173412..1174388 (-) 977 Protein_1124 LacI family DNA-binding transcriptional regulator -
  ETT54_RS05990 (ETT54_05985) sepM 1174802..1175839 (-) 1038 WP_136098239.1 SepM family pheromone-processing serine protease Regulator
  ETT54_RS05995 (ETT54_05990) coaD 1175826..1176317 (-) 492 WP_002983821.1 pantetheine-phosphate adenylyltransferase -
  ETT54_RS06000 (ETT54_05995) rsmD 1176307..1176846 (-) 540 WP_002983819.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  ETT54_RS06005 (ETT54_06000) asnA 1176969..1177961 (-) 993 WP_010922500.1 aspartate--ammonia ligase -
  ETT54_RS06010 (ETT54_06005) arcC 1178274..1179224 (-) 951 WP_063631992.1 carbamate kinase -
  ETT54_RS06015 (ETT54_06010) - 1179244..1180575 (-) 1332 WP_009880963.1 dipeptidase -

Sequence

Protein


Download         Length: 345 a.a.        Molecular weight: 37569.30 Da        Isoelectric Point: 9.6692

>NTDB_id=341978 ETT54_RS05990 WP_136098239.1 1174802..1175839(-) (sepM) [Streptococcus pyogenes strain emm92]
MKRLKKIKWWLVGLLALISLLLALFFPLPYYIEMPGGAYDIRTVLQVNGKEDKRKGAYQFVAVGISRASLAQLLYAWLTP
FTEISTVEDTTGGYSDADFLRINQFYMETSQNAAIYQALSLAGKPVTLDYKGVYVLDVNNESTFKGTLHLADTVTGVNGK
QFTSSAELIDYVSHLKLGDEVTVQFTSDNKPKKGVGRIIKLKNGKNGIGIALTDHTSVNSEDTVIFSTKGVGGPSAGLMF
TLDIYDQITKEDLRKGRTIAGTGTIGKDGEVGDIGGAGLKVVAAAEAGADIFFVPNNPVDKEIKKVNPNAISNYEEAKRA
AKRLKTKMKIVPVTTVQEALVYLRK

Nucleotide


Download         Length: 1038 bp        

>NTDB_id=341978 ETT54_RS05990 WP_136098239.1 1174802..1175839(-) (sepM) [Streptococcus pyogenes strain emm92]
ATGAAAAGACTTAAAAAAATCAAATGGTGGTTAGTGGGTCTGCTAGCTTTAATCTCTTTGTTGCTAGCGTTATTTTTTCC
GCTACCTTATTATATTGAAATGCCTGGAGGCGCTTACGATATTCGGACTGTCTTACAAGTCAATGGCAAAGAAGACAAAC
GAAAAGGAGCTTACCAGTTTGTTGCAGTGGGCATTAGTCGTGCCAGCCTCGCTCAGCTATTATATGCTTGGCTGACACCG
TTTACTGAAATTAGTACAGTAGAAGATACAACAGGCGGATACAGCGATGCTGATTTCCTTCGAATTAATCAATTTTACAT
GGAAACATCACAAAATGCAGCTATTTATCAAGCTTTATCCTTAGCTGGAAAACCAGTTACATTAGATTATAAAGGCGTAT
ATGTTTTAGACGTAAACAACGAATCTACTTTTAAAGGAACGCTACACTTAGCAGATACTGTAACAGGTGTAAATGGTAAA
CAGTTTACTAGTTCAGCAGAACTTATTGACTATGTTTCTCACCTAAAACTAGGGGATGAAGTTACGGTTCAGTTTACGAG
TGATAATAAGCCTAAAAAAGGAGTTGGCCGTATTATCAAACTGAAAAATGGGAAAAATGGGATTGGCATTGCCTTGACTG
ATCATACAAGTGTCAATTCAGAAGACACAGTGATCTTTAGTACTAAAGGAGTAGGAGGACCTAGTGCTGGTCTAATGTTT
ACTCTTGATATATATGATCAAATAACTAAAGAAGATTTACGCAAGGGCCGTACAATTGCAGGTACAGGAACTATTGGCAA
GGATGGCGAAGTAGGAGATATTGGTGGTGCAGGTCTTAAAGTAGTTGCAGCAGCTGAAGCTGGTGCAGATATATTTTTTG
TTCCGAATAATCCTGTTGATAAGGAAATTAAAAAAGTTAATCCAAATGCTATAAGTAATTACGAAGAAGCCAAACGGGCA
GCCAAACGACTAAAGACCAAAATGAAGATTGTTCCTGTTACGACTGTTCAAGAGGCACTGGTTTATCTTCGCAAATAA

Domains

Predicted by InterproScan.

Lon protease (S16) C-terminal proteolytic domain (Lon_C)

(233-309)

PDZ domain (PDZ_2)

(129-192)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sepM Streptococcus mutans UA159

68.986

100

0.69

Multiple sequence alignment