Detailed information
Bioinformatically predicted
Overview
| Name | pepF | Type | Regulator |
| Locus tag | ETT55_RS05650 | Genome accession | NZ_CP035444 |
| Coordinates | 1111690..1113495 (-) | Length | 601 a.a. |
| NCBI ID | WP_030126417.1 | Uniprot ID | - |
| Organism | Streptococcus pyogenes strain emm90.5 | ||
| Function | degradation of XIP; competence shut-off (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 1091437..1138491 | 1111690..1113495 | within | 0 |
Gene organization within MGE regions
Location: 1091437..1138491
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| ETT55_RS05570 (ETT55_05560) | - | 1091475..1092749 (-) | 1275 | WP_002989251.1 | polysaccharide deacetylase family protein | - |
| ETT55_RS05575 (ETT55_05565) | - | 1092844..1094271 (-) | 1428 | WP_030126519.1 | NADP-dependent glyceraldehyde-3-phosphate dehydrogenase | - |
| ETT55_RS05580 (ETT55_05570) | ptsP | 1094438..1096171 (-) | 1734 | WP_030126520.1 | phosphoenolpyruvate--protein phosphotransferase | - |
| ETT55_RS05585 (ETT55_05575) | - | 1096176..1096439 (-) | 264 | WP_002984031.1 | phosphocarrier protein HPr | - |
| ETT55_RS05590 (ETT55_05580) | nrdH | 1096832..1097050 (+) | 219 | WP_030126521.1 | glutaredoxin-like protein NrdH | - |
| ETT55_RS05595 (ETT55_05585) | nrdE | 1097070..1099229 (+) | 2160 | WP_136021736.1 | class 1b ribonucleoside-diphosphate reductase subunit alpha | - |
| ETT55_RS05600 (ETT55_05590) | nrdF | 1099562..1100521 (+) | 960 | WP_030126523.1 | class 1b ribonucleoside-diphosphate reductase subunit beta | - |
| ETT55_RS05605 (ETT55_05595) | - | 1100496..1101809 (+) | 1314 | WP_111717962.1 | chloride channel protein | - |
| ETT55_RS05610 (ETT55_05600) | - | 1101948..1103083 (+) | 1136 | Protein_1031 | IS3 family transposase | - |
| ETT55_RS05615 (ETT55_05605) | - | 1103175..1103870 (-) | 696 | WP_111689540.1 | CPBP family intramembrane glutamic endopeptidase | - |
| ETT55_RS05620 (ETT55_05610) | - | 1103889..1104650 (-) | 762 | WP_053308456.1 | DUF3169 family protein | - |
| ETT55_RS05625 (ETT55_05615) | - | 1104647..1104862 (-) | 216 | WP_002989220.1 | helix-turn-helix transcriptional regulator | - |
| ETT55_RS05630 (ETT55_05620) | alaS | 1105223..1107841 (-) | 2619 | WP_011284933.1 | alanine--tRNA ligase | - |
| ETT55_RS05635 (ETT55_05625) | prsA | 1108228..1109283 (-) | 1056 | WP_111717964.1 | peptidylprolyl isomerase PrsA | - |
| ETT55_RS05640 (ETT55_05630) | - | 1109346..1110053 (-) | 708 | WP_002989211.1 | O-methyltransferase | - |
| ETT55_RS05645 (ETT55_05635) | - | 1110119..1111315 (-) | 1197 | WP_002995765.1 | OFA family MFS transporter | - |
| ETT55_RS05650 (ETT55_05640) | pepF | 1111690..1113495 (-) | 1806 | WP_030126417.1 | oligoendopeptidase F | Regulator |
| ETT55_RS05655 (ETT55_05645) | - | 1113508..1114471 (-) | 964 | Protein_1040 | competence protein CoiA | - |
| ETT55_RS05660 (ETT55_05650) | - | 1114766..1115482 (-) | 717 | WP_030126416.1 | pseudouridine synthase | - |
| ETT55_RS05665 (ETT55_05655) | nagB | 1115556..1116305 (-) | 750 | WP_136021735.1 | glucosamine-6-phosphate deaminase | - |
| ETT55_RS05670 (ETT55_05660) | queA | 1116507..1117535 (+) | 1029 | WP_011284937.1 | tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA | - |
| ETT55_RS05675 (ETT55_05665) | - | 1117542..1118762 (+) | 1221 | WP_030126414.1 | DUF3114 domain-containing protein | - |
| ETT55_RS05680 (ETT55_05670) | - | 1118876..1119466 (-) | 591 | WP_011528765.1 | serine hydrolase | - |
| ETT55_RS05685 (ETT55_05675) | - | 1119463..1119711 (-) | 249 | WP_010922432.1 | serine hydrolase | - |
| ETT55_RS05690 (ETT55_05680) | - | 1119696..1119923 (-) | 228 | WP_030126413.1 | hypothetical protein | - |
| ETT55_RS05695 (ETT55_05685) | sodA | 1120090..1120695 (-) | 606 | WP_002983977.1 | superoxide dismutase SodA | - |
| ETT55_RS05700 (ETT55_05690) | holA | 1120792..1121832 (-) | 1041 | WP_030126412.1 | DNA polymerase III subunit delta | - |
| ETT55_RS05705 (ETT55_05695) | - | 1121903..1124146 (-) | 2244 | WP_030126411.1 | DNA internalization-related competence protein ComEC/Rec2 | - |
| ETT55_RS05710 (ETT55_05700) | - | 1124127..1124789 (-) | 663 | WP_002983967.1 | ComEA family DNA-binding protein | - |
| ETT55_RS05715 (ETT55_05705) | - | 1124989..1125729 (-) | 741 | WP_002989170.1 | 1-acyl-sn-glycerol-3-phosphate acyltransferase | - |
| ETT55_RS05720 (ETT55_05710) | - | 1125847..1126623 (+) | 777 | WP_010922438.1 | tRNA1(Val) (adenine(37)-N6)-methyltransferase | - |
| ETT55_RS05725 (ETT55_05715) | - | 1126613..1126891 (+) | 279 | WP_002989164.1 | GIY-YIG nuclease family protein | - |
| ETT55_RS05730 (ETT55_05720) | - | 1126915..1128915 (-) | 2001 | WP_030126409.1 | potassium transporter Kup | - |
| ETT55_RS05735 (ETT55_05725) | - | 1129043..1130662 (-) | 1620 | WP_002989158.1 | DEAD/DEAH box helicase | - |
| ETT55_RS05740 (ETT55_05730) | - | 1130969..1132513 (-) | 1545 | WP_002989155.1 | peptide chain release factor 3 | - |
| ETT55_RS05750 (ETT55_05740) | - | 1132761..1133456 (-) | 696 | WP_030126408.1 | TIGR02206 family membrane protein | - |
| ETT55_RS05755 (ETT55_05745) | murF | 1133536..1134927 (-) | 1392 | WP_010922441.1 | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase | - |
| ETT55_RS05760 (ETT55_05750) | - | 1135118..1136164 (-) | 1047 | WP_030126407.1 | D-alanine--D-alanine ligase | - |
| ETT55_RS05765 (ETT55_05755) | recR | 1136265..1136861 (-) | 597 | WP_002983939.1 | recombination mediator RecR | - |
| ETT55_RS09050 (ETT55_05760) | - | 1136908..1137099 (-) | 192 | WP_002983936.1 | hypothetical protein | - |
| ETT55_RS05775 (ETT55_05765) | - | 1137660..1138439 (-) | 780 | WP_002989141.1 | formate/nitrite transporter family protein | - |
Sequence
Protein
Download Length: 601 a.a. Molecular weight: 69395.39 Da Isoelectric Point: 4.7743
>NTDB_id=341921 ETT55_RS05650 WP_030126417.1 1111690..1113495(-) (pepF) [Streptococcus pyogenes strain emm90.5]
MTDNRSHLEEKYTWDLSTIFATDKDWEAEVSDLATEVEASKGFAGHLLDSSANLLKVTKTYLELARRVEKVYVYAHMKND
QDTTVAKYQEYQAKASGLYAKFSEVFSFYDPEVMMLHQEDYQAFLTETPELKVYNHFFDKLFQAREHVLSQAEEELLAGA
QEIFNGAEETFSILDNADIVFPIVRNDKGENVELTHGNFISLMESKDRSVRQAAYEAMYSTYEQFQHTYAKTLQTNVKVQ
NYKARVHKYDSARQAAMAANFIPEAVYDTLLETVNKHLPLLHRYLKLRQEVLGLDDLKMYDVYTPLSETDLAIGYDEALE
KAEKVLAVFGKDYADRVHRAFTERWIDVHVNKGKRSGAYSGGSYDTNAFMLLNWQDTLDNLYTLVHETGHSLHSTFTRET
QPYVYGDYSIFLAEIASTTNENIMTEALLNEVQDEKERFAILNHYLDGFRGTVFRQTQFAEFEHAIHQADQKGEVLTSEY
LNQLYADLNEKYYGLSKKDNHFIQYEWARIPHFYYNYYVYQYATGFAAASYLADEIVHGTQDDIDHYLAYLKSGNSDYPL
EVIAKAGVDMAKGDYLEAAFKVFDERLTELEVLVSKGIHKS
MTDNRSHLEEKYTWDLSTIFATDKDWEAEVSDLATEVEASKGFAGHLLDSSANLLKVTKTYLELARRVEKVYVYAHMKND
QDTTVAKYQEYQAKASGLYAKFSEVFSFYDPEVMMLHQEDYQAFLTETPELKVYNHFFDKLFQAREHVLSQAEEELLAGA
QEIFNGAEETFSILDNADIVFPIVRNDKGENVELTHGNFISLMESKDRSVRQAAYEAMYSTYEQFQHTYAKTLQTNVKVQ
NYKARVHKYDSARQAAMAANFIPEAVYDTLLETVNKHLPLLHRYLKLRQEVLGLDDLKMYDVYTPLSETDLAIGYDEALE
KAEKVLAVFGKDYADRVHRAFTERWIDVHVNKGKRSGAYSGGSYDTNAFMLLNWQDTLDNLYTLVHETGHSLHSTFTRET
QPYVYGDYSIFLAEIASTTNENIMTEALLNEVQDEKERFAILNHYLDGFRGTVFRQTQFAEFEHAIHQADQKGEVLTSEY
LNQLYADLNEKYYGLSKKDNHFIQYEWARIPHFYYNYYVYQYATGFAAASYLADEIVHGTQDDIDHYLAYLKSGNSDYPL
EVIAKAGVDMAKGDYLEAAFKVFDERLTELEVLVSKGIHKS
Nucleotide
Download Length: 1806 bp
>NTDB_id=341921 ETT55_RS05650 WP_030126417.1 1111690..1113495(-) (pepF) [Streptococcus pyogenes strain emm90.5]
ATGACTGATAATCGCAGCCATTTAGAAGAAAAATACACTTGGGATTTGAGCACTATTTTTGCAACAGATAAGGATTGGGA
AGCTGAAGTCAGTGACTTAGCTACTGAAGTTGAGGCATCTAAAGGTTTTGCTGGTCATTTGCTGGATTCTAGTGCTAATT
TGTTAAAGGTTACAAAAACATATTTAGAATTGGCTCGTCGTGTGGAGAAAGTCTATGTTTATGCTCACATGAAAAATGAC
CAAGACACTACTGTTGCCAAGTATCAAGAATACCAAGCTAAGGCTTCAGGCTTGTATGCAAAGTTTAGCGAAGTCTTTTC
ATTCTATGATCCAGAAGTGATGATGCTTCATCAAGAAGACTATCAGGCTTTCCTTACTGAAACCCCTGAGTTGAAAGTGT
ACAACCATTTCTTTGACAAATTATTCCAAGCCCGCGAACATGTTCTTAGTCAAGCAGAAGAGGAATTATTAGCAGGAGCT
CAAGAAATTTTCAATGGTGCGGAAGAAACCTTTAGTATTCTTGATAACGCTGACATTGTTTTCCCGATAGTCAGAAATGA
TAAAGGTGAAAACGTTGAATTAACCCATGGTAACTTCATTAGCCTAATGGAATCTAAGGACCGTAGCGTTCGCCAAGCTG
CTTATGAAGCCATGTATAGTACTTATGAACAGTTCCAACATACTTACGCTAAAACCTTGCAAACCAATGTGAAAGTGCAA
AACTATAAGGCGCGTGTTCATAAATACGATTCAGCACGTCAAGCTGCCATGGCTGCTAACTTTATTCCAGAAGCTGTTTA
CGACACTTTATTAGAAACGGTTAACAAACATTTACCACTCTTACACCGTTATTTGAAATTGCGTCAAGAGGTTCTTGGTT
TAGACGATTTGAAGATGTATGATGTTTACACACCATTATCTGAAACAGATTTAGCCATTGGTTATGATGAGGCTTTGGAA
AAGGCTGAGAAGGTTTTGGCTGTTTTTGGTAAAGATTACGCAGATCGTGTACATCGTGCTTTTACCGAACGTTGGATTGA
TGTTCACGTCAATAAAGGGAAGCGCTCTGGGGCTTATTCAGGTGGTTCCTATGATACCAATGCCTTCATGCTGTTGAACT
GGCAAGATACACTTGATAATCTTTACACACTTGTCCACGAAACAGGCCACAGTTTGCATTCTACTTTCACTCGTGAAACA
CAGCCTTATGTGTATGGGGATTATAGTATCTTCTTGGCAGAAATTGCATCCACAACGAATGAAAACATCATGACAGAAGC
TCTCTTAAATGAAGTGCAAGATGAGAAAGAACGCTTTGCCATTTTAAACCATTACCTCGATGGTTTCCGTGGAACAGTTT
TCCGTCAAACCCAATTTGCTGAGTTTGAACATGCCATTCATCAAGCTGATCAAAAAGGAGAAGTGTTAACAAGTGAATAC
CTTAACCAGCTATACGCTGATTTAAATGAAAAATATTATGGTTTAAGTAAAAAAGATAATCATTTTATTCAGTATGAATG
GGCACGTATTCCTCATTTCTATTACAATTATTATGTTTACCAATATGCAACAGGTTTTGCAGCTGCAAGCTATTTAGCGG
ATGAGATTGTGCATGGCACACAAGACGATATCGATCATTACTTGGCCTACCTCAAGTCAGGAAATTCTGATTACCCACTT
GAAGTGATTGCTAAAGCAGGCGTTGATATGGCAAAAGGTGATTATTTGGAAGCCGCCTTTAAAGTCTTTGACGAACGTCT
AACAGAACTTGAAGTACTCGTGTCCAAAGGCATACACAAAAGCTAA
ATGACTGATAATCGCAGCCATTTAGAAGAAAAATACACTTGGGATTTGAGCACTATTTTTGCAACAGATAAGGATTGGGA
AGCTGAAGTCAGTGACTTAGCTACTGAAGTTGAGGCATCTAAAGGTTTTGCTGGTCATTTGCTGGATTCTAGTGCTAATT
TGTTAAAGGTTACAAAAACATATTTAGAATTGGCTCGTCGTGTGGAGAAAGTCTATGTTTATGCTCACATGAAAAATGAC
CAAGACACTACTGTTGCCAAGTATCAAGAATACCAAGCTAAGGCTTCAGGCTTGTATGCAAAGTTTAGCGAAGTCTTTTC
ATTCTATGATCCAGAAGTGATGATGCTTCATCAAGAAGACTATCAGGCTTTCCTTACTGAAACCCCTGAGTTGAAAGTGT
ACAACCATTTCTTTGACAAATTATTCCAAGCCCGCGAACATGTTCTTAGTCAAGCAGAAGAGGAATTATTAGCAGGAGCT
CAAGAAATTTTCAATGGTGCGGAAGAAACCTTTAGTATTCTTGATAACGCTGACATTGTTTTCCCGATAGTCAGAAATGA
TAAAGGTGAAAACGTTGAATTAACCCATGGTAACTTCATTAGCCTAATGGAATCTAAGGACCGTAGCGTTCGCCAAGCTG
CTTATGAAGCCATGTATAGTACTTATGAACAGTTCCAACATACTTACGCTAAAACCTTGCAAACCAATGTGAAAGTGCAA
AACTATAAGGCGCGTGTTCATAAATACGATTCAGCACGTCAAGCTGCCATGGCTGCTAACTTTATTCCAGAAGCTGTTTA
CGACACTTTATTAGAAACGGTTAACAAACATTTACCACTCTTACACCGTTATTTGAAATTGCGTCAAGAGGTTCTTGGTT
TAGACGATTTGAAGATGTATGATGTTTACACACCATTATCTGAAACAGATTTAGCCATTGGTTATGATGAGGCTTTGGAA
AAGGCTGAGAAGGTTTTGGCTGTTTTTGGTAAAGATTACGCAGATCGTGTACATCGTGCTTTTACCGAACGTTGGATTGA
TGTTCACGTCAATAAAGGGAAGCGCTCTGGGGCTTATTCAGGTGGTTCCTATGATACCAATGCCTTCATGCTGTTGAACT
GGCAAGATACACTTGATAATCTTTACACACTTGTCCACGAAACAGGCCACAGTTTGCATTCTACTTTCACTCGTGAAACA
CAGCCTTATGTGTATGGGGATTATAGTATCTTCTTGGCAGAAATTGCATCCACAACGAATGAAAACATCATGACAGAAGC
TCTCTTAAATGAAGTGCAAGATGAGAAAGAACGCTTTGCCATTTTAAACCATTACCTCGATGGTTTCCGTGGAACAGTTT
TCCGTCAAACCCAATTTGCTGAGTTTGAACATGCCATTCATCAAGCTGATCAAAAAGGAGAAGTGTTAACAAGTGAATAC
CTTAACCAGCTATACGCTGATTTAAATGAAAAATATTATGGTTTAAGTAAAAAAGATAATCATTTTATTCAGTATGAATG
GGCACGTATTCCTCATTTCTATTACAATTATTATGTTTACCAATATGCAACAGGTTTTGCAGCTGCAAGCTATTTAGCGG
ATGAGATTGTGCATGGCACACAAGACGATATCGATCATTACTTGGCCTACCTCAAGTCAGGAAATTCTGATTACCCACTT
GAAGTGATTGCTAAAGCAGGCGTTGATATGGCAAAAGGTGATTATTTGGAAGCCGCCTTTAAAGTCTTTGACGAACGTCT
AACAGAACTTGAAGTACTCGTGTCCAAAGGCATACACAAAAGCTAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| pepF | Streptococcus salivarius strain HSISS4 |
70.549 |
100 |
0.705 |