Detailed information    

insolico Bioinformatically predicted

Overview

Name   comS   Type   Regulator
Locus tag   ETT59_RS09300 Genome accession   NZ_CP035440
Coordinates   53845..53940 (+) Length   31 a.a.
NCBI ID   WP_198462994.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain emm124     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 48845..58940
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ETT59_RS00320 (ETT59_00320) purK 48913..49986 (+) 1074 WP_186800977.1 5-(carboxyamino)imidazole ribonucleotide synthase -
  ETT59_RS00325 (ETT59_00325) - 49988..51406 (+) 1419 WP_011888524.1 hypothetical protein -
  ETT59_RS00330 (ETT59_00330) purB 51427..52719 (+) 1293 WP_014407197.1 adenylosuccinate lyase -
  ETT59_RS00335 (ETT59_00335) comR 52850..53761 (+) 912 WP_002986681.1 transcriptional regulator Rgg4/ComR Regulator
  ETT59_RS09300 comS 53845..53940 (+) 96 WP_198462994.1 quorum-sensing system DWW-type pheromone Regulator
  ETT59_RS00340 (ETT59_00340) ruvB 53987..54985 (+) 999 WP_053308139.1 Holliday junction branch migration DNA helicase RuvB -
  ETT59_RS00345 (ETT59_00345) - 55123..55560 (+) 438 WP_002994668.1 low molecular weight protein-tyrosine-phosphatase -
  ETT59_RS00350 (ETT59_00350) - 55583..55984 (+) 402 WP_012560369.1 MORN repeat-containing protein -
  ETT59_RS00355 (ETT59_00355) - 55981..57756 (+) 1776 WP_053308140.1 acyltransferase family protein -

Sequence

Protein


Download         Length: 31 a.a.        Molecular weight: 3857.66 Da        Isoelectric Point: 10.0436

>NTDB_id=341724 ETT59_RS09300 WP_198462994.1 53845..53940(+) (comS) [Streptococcus pyogenes strain emm124]
MLKKYKYYFIFAALLSFKVVQELSAVDWWRL

Nucleotide


Download         Length: 96 bp        

>NTDB_id=341724 ETT59_RS09300 WP_198462994.1 53845..53940(+) (comS) [Streptococcus pyogenes strain emm124]
ATGTTAAAAAAGTATAAGTACTATTTTATATTCGCAGCTCTACTATCTTTTAAAGTAGTTCAAGAGCTTAGTGCTGTTGA
CTGGTGGCGATTATAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comS Streptococcus pyogenes MGAS8232

100

100

1
  comS Streptococcus pyogenes MGAS315

45.161

100

0.452

Multiple sequence alignment