Detailed information NTG0341696

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: ETT59_RS03170
• Genome accession: NZ_CP035440
• Coordinates: 605875..606912 (+)
• Length: 345 a.a.
• NCBI ID: WP_111684731.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain emm124
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 600875..611912

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ETT59_RS03145 (ETT59_03145)	-	601139..602470 (+)	1332	WP_032460502.1	dipeptidase	-
ETT59_RS03150 (ETT59_03150)	arcC	602490..603440 (+)	951	WP_136276429.1	carbamate kinase	-
ETT59_RS03155 (ETT59_03155)	asnA	603753..604745 (+)	993	WP_023611792.1	aspartate--ammonia ligase	-
ETT59_RS03160 (ETT59_03160)	rsmD	604868..605407 (+)	540	WP_002983819.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
ETT59_RS03165 (ETT59_03165)	coaD	605397..605888 (+)	492	WP_002983821.1	pantetheine-phosphate adenylyltransferase	-
ETT59_RS03170 (ETT59_03170)	sepM	605875..606912 (+)	1038	WP_111684731.1	SepM family pheromone-processing serine protease	Regulator
ETT59_RS03175 (ETT59_03175)	-	607317..608294 (+)	978	WP_002994809.1	LacI family DNA-binding transcriptional regulator	-
ETT59_RS03180 (ETT59_03180)	-	608742..609362 (+)	621	WP_002992791.1	YutD family protein	-
ETT59_RS03185 (ETT59_03185)	rlmN	609366..610445 (+)	1080	WP_002992788.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
ETT59_RS03190 (ETT59_03190)	-	610527..611153 (-)	627	WP_002983834.1	A24 family peptidase	-
ETT59_RS03195 (ETT59_03195)	-	611381..611908 (+)	528	WP_002983837.1	Dps family protein	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37571.27 Da
• Isoelectric Point: 9.6692

>NTDB_id=341696 ETT59_RS03170 WP_111684731.1 605875..606912(+) (sepM) [Streptococcus pyogenes strain emm124]
MKRLKKIKWWLVGLLALISLLLALFFPLPYYIEMPGGAYDIRTVLQVNGKEDKRKGAYQFVAVGISRASLAQLLYAWLTP
FTEISTAEDTTGGYSDADFLRINQFYMETSQNAAIYQALSLAGKPVTLDYKGVYVLDVNNESTFKGTLHLADTVTGVNGK
QFTSSAELIDYVSHLKLGDEVTIQFTSDNKPKKGVGRIIKLKNGKNGIGIALTDHTSVNSEDTVIFSTKGVGGPSAGLMF
TLDIYDQITKEDLRKGRTIAGTGTIGKDGEVGDIGGAGLKVVAAAEAGADIFFVPNNPVDKEIKKVNPNAISNYEEAKRS
AKRLKTKMKIVPVTTVQEALVYLRK

Nucleotide

• Length: 1038 bp

>NTDB_id=341696 ETT59_RS03170 WP_111684731.1 605875..606912(+) (sepM) [Streptococcus pyogenes strain emm124]
ATGAAAAGACTTAAAAAAATCAAATGGTGGTTAGTGGGTCTGCTAGCTTTAATCTCTTTGTTGCTAGCGTTATTTTTTCC
GCTACCTTATTATATTGAAATGCCTGGAGGCGCTTACGATATTCGGACTGTCTTACAAGTCAATGGCAAAGAAGACAAAC
GAAAAGGAGCTTACCAGTTTGTTGCAGTGGGCATTAGTCGTGCCAGCCTCGCTCAGCTATTATATGCTTGGCTGACACCG
TTTACTGAAATTAGTACAGCAGAAGATACAACAGGCGGATACAGCGATGCTGATTTCCTTCGAATTAATCAATTTTACAT
GGAAACATCACAAAATGCAGCTATTTATCAAGCTTTATCCTTAGCTGGCAAACCAGTTACATTAGATTATAAAGGCGTAT
ATGTTTTAGACGTAAACAACGAATCTACTTTTAAAGGAACGTTACACTTAGCAGATACTGTAACAGGTGTAAATGGTAAA
CAGTTTACTAGTTCAGCAGAACTTATTGACTATGTTTCTCACCTAAAACTAGGGGATGAAGTTACGATTCAGTTTACGAG
TGATAATAAGCCTAAAAAAGGAGTTGGCCGTATTATCAAACTGAAAAATGGGAAAAATGGGATTGGCATTGCCTTGACTG
ATCATACAAGTGTCAATTCAGAAGACACAGTGATCTTTAGTACTAAAGGAGTAGGAGGACCCAGTGCTGGTCTAATGTTT
ACTCTTGATATATATGATCAAATAACTAAAGAAGATTTACGCAAGGGCCGTACAATTGCAGGTACAGGAACTATTGGCAA
GGATGGCGAAGTAGGAGATATTGGTGGTGCAGGTCTTAAAGTAGTTGCAGCAGCTGAAGCTGGTGCAGATATATTTTTTG
TTCCGAATAATCCTGTTGATAAGGAAATTAAAAAAGTTAATCCAAATGCTATAAGTAATTACGAAGAAGCCAAACGGTCA
GCCAAACGACTAAAGACCAAAATGAAGATTGTTCCTGTTACGACTGTTCAAGAGGCACTGGTTTATCTTCGCAAATAG

Domains

Predicted by InterproScan.

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (233-309)

• PDZ domain (PDZ_2) (129-192)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	68.696	100	0.687