Detailed information NTG0341631

Bioinformatically predicted

Overview

• Name: amiE
• Type: Regulator
• Locus tag: ETT60_RS01440
• Genome accession: NZ_CP035439
• Coordinates: 265135..266205 (+)
• Length: 356 a.a.
• NCBI ID: WP_023612409.1
• Uniprot ID: A0A5S4TIQ7
• Organism: Streptococcus pyogenes strain emm77
• Function: internalize XIP (predicted from homology) Competence regulation

Genomic Context

Location: 260135..271205

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ETT60_RS01425 (ETT60_01425)	amiA	260663..262633 (+)	1971	WP_024623426.1	peptide ABC transporter substrate-binding protein	Regulator
ETT60_RS01430 (ETT60_01430)	amiC	262698..264200 (+)	1503	WP_002991105.1	ABC transporter permease	Regulator
ETT60_RS01435 (ETT60_01435)	amiD	264200..265126 (+)	927	WP_002986004.1	oligopeptide ABC transporter permease OppC	Regulator
ETT60_RS01440 (ETT60_01440)	amiE	265135..266205 (+)	1071	WP_023612409.1	ABC transporter ATP-binding protein	Regulator
ETT60_RS01445 (ETT60_01445)	amiF	266198..267121 (+)	924	WP_002986000.1	ABC transporter ATP-binding protein	Regulator
ETT60_RS09415 (ETT60_01450)	-	267159..267251 (-)	93	WP_115230800.1	IS3 family transposase	-
ETT60_RS01455 (ETT60_01455)	-	267269..267463 (-)	195	WP_227868546.1	transposase	-

Sequence

Protein

• Length: 356 a.a.
• Molecular weight: 39689.75 Da
• Isoelectric Point: 5.6686

>NTDB_id=341631 ETT60_RS01440 WP_023612409.1 265135..266205(+) (amiE) [Streptococcus pyogenes strain emm77]
MTKENNVILTAKDVVVEFDVRDRVLTAIRNVSLELVEGEVLAFVGESGSGKSVLTKTFTGMLESNGRIANGSIVYRGQEL
TDLKTNKEWAKIRGSKIATIFQDPMTSLSPIKTIGSQITEVIIKHQKVSHAKAKEMALDYMNKVGIPNAKKRFEDYPFEY
SGGMRQRIVIAIALACRPDILICDEPTTALDVTIQAQIVELLKSLQREYHFTIIFITHDLGVVASIADKVAVMYAGEIVE
FGTVEEIFYDPRHPYTWSLLSSLPQLADDSGELYAIPGTPPSLYSPIIGDAFALRSEYAMVLDFEKAPPAINVSETHWAK
TWLLHPEAPKVQKPEVIQDLHQKILRKMSQQEEGNV

Nucleotide

• Length: 1071 bp

>NTDB_id=341631 ETT60_RS01440 WP_023612409.1 265135..266205(+) (amiE) [Streptococcus pyogenes strain emm77]
ATGACAAAAGAAAATAATGTAATCTTAACTGCCAAAGATGTGGTGGTAGAATTTGATGTGCGTGATCGTGTTTTAACAGC
TATCCGTAACGTCTCATTGGAACTTGTTGAAGGAGAAGTCCTTGCTTTTGTAGGGGAATCAGGCTCAGGTAAATCTGTTT
TAACAAAGACCTTTACAGGGATGTTGGAGTCTAATGGACGCATTGCTAATGGTTCAATTGTCTATCGTGGGCAAGAATTG
ACAGATTTAAAAACAAATAAAGAGTGGGCAAAGATTCGCGGCTCAAAAATCGCAACGATTTTCCAAGACCCAATGACCAG
TCTTAGTCCCATTAAAACTATCGGTAGCCAAATCACAGAAGTGATTATTAAGCACCAAAAAGTAAGTCATGCCAAAGCTA
AAGAAATGGCCCTTGATTACATGAATAAAGTGGGTATCCCAAATGCCAAAAAACGCTTTGAAGATTACCCATTTGAGTAT
TCAGGAGGAATGCGTCAACGTATTGTTATCGCTATTGCTTTAGCTTGTCGCCCAGATATTCTTATCTGTGATGAGCCAAC
AACAGCCCTTGATGTGACTATTCAAGCTCAAATCGTTGAGTTATTGAAGTCGCTTCAACGAGAATATCATTTCACCATTA
TCTTTATTACGCACGATTTAGGTGTTGTGGCAAGCATTGCAGATAAAGTGGCTGTCATGTATGCAGGAGAAATTGTTGAA
TTTGGAACAGTCGAAGAGATTTTCTATGATCCAAGACACCCCTATACATGGAGTTTGCTGTCTAGCTTACCGCAGTTGGC
AGATGATTCTGGTGAACTTTACGCTATTCCAGGAACGCCTCCATCACTTTATTCACCAATTATCGGAGATGCCTTTGCAC
TTCGCTCAGAATATGCTATGGTTTTAGACTTTGAAAAAGCACCTCCGGCGATTAACGTATCTGAGACTCATTGGGCCAAA
ACATGGCTTTTACACCCAGAGGCTCCAAAAGTTCAAAAACCAGAAGTCATTCAAGATTTGCATCAAAAAATCTTAAGGAA
AATGTCACAACAGGAGGAAGGAAATGTCTGA

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (29-187)

• Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY) (239-299)

3D structure

• AlphaFold DB: A0A5S4TIQ7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
amiE	Streptococcus salivarius strain HSISS4	76.944	100	0.778
amiE	Streptococcus thermophilus LMG 18311	75.833	100	0.767
amiE	Streptococcus thermophilus LMD-9	75.833	100	0.767
oppD	Streptococcus mutans UA159	56.677	94.663	0.537