Detailed information NTG0341484

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: ETT63_RS03015
• Genome accession: NZ_CP035436
• Coordinates: 583987..585024 (+)
• Length: 345 a.a.
• NCBI ID: WP_111684731.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain emm89.14
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 578987..590024

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ETT63_RS02990 (ETT63_02990)	-	579251..580582 (+)	1332	WP_111676254.1	dipeptidase	-
ETT63_RS02995 (ETT63_02995)	arcC	580602..581552 (+)	951	WP_015057899.1	carbamate kinase	-
ETT63_RS03000 (ETT63_03000)	asnA	581865..582857 (+)	993	WP_023611792.1	aspartate--ammonia ligase	-
ETT63_RS03005 (ETT63_03005)	rsmD	582980..583519 (+)	540	WP_002983819.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
ETT63_RS03010 (ETT63_03010)	coaD	583509..584000 (+)	492	WP_136267705.1	pantetheine-phosphate adenylyltransferase	-
ETT63_RS03015 (ETT63_03015)	sepM	583987..585024 (+)	1038	WP_111684731.1	SepM family pheromone-processing serine protease	Regulator
ETT63_RS03020 (ETT63_03020)	-	585429..586406 (+)	978	WP_002994809.1	LacI family DNA-binding transcriptional regulator	-
ETT63_RS03025 (ETT63_03025)	-	586854..587474 (+)	621	WP_002992791.1	YutD family protein	-
ETT63_RS03030 (ETT63_03030)	rlmN	587478..588557 (+)	1080	WP_002992788.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
ETT63_RS03035 (ETT63_03035)	-	588639..589265 (-)	627	WP_136267707.1	A24 family peptidase	-
ETT63_RS03040 (ETT63_03040)	-	589493..590020 (+)	528	WP_002983837.1	Dps family protein	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37571.27 Da
• Isoelectric Point: 9.6692

>NTDB_id=341484 ETT63_RS03015 WP_111684731.1 583987..585024(+) (sepM) [Streptococcus pyogenes strain emm89.14]
MKRLKKIKWWLVGLLALISLLLALFFPLPYYIEMPGGAYDIRTVLQVNGKEDKRKGAYQFVAVGISRASLAQLLYAWLTP
FTEISTAEDTTGGYSDADFLRINQFYMETSQNAAIYQALSLAGKPVTLDYKGVYVLDVNNESTFKGTLHLADTVTGVNGK
QFTSSAELIDYVSHLKLGDEVTIQFTSDNKPKKGVGRIIKLKNGKNGIGIALTDHTSVNSEDTVIFSTKGVGGPSAGLMF
TLDIYDQITKEDLRKGRTIAGTGTIGKDGEVGDIGGAGLKVVAAAEAGADIFFVPNNPVDKEIKKVNPNAISNYEEAKRS
AKRLKTKMKIVPVTTVQEALVYLRK

Nucleotide

• Length: 1038 bp

>NTDB_id=341484 ETT63_RS03015 WP_111684731.1 583987..585024(+) (sepM) [Streptococcus pyogenes strain emm89.14]
ATGAAAAGACTTAAAAAAATCAAATGGTGGTTAGTGGGTCTGCTAGCTTTAATCTCTTTGTTGCTAGCGTTATTTTTTCC
GCTACCTTATTATATTGAAATGCCTGGAGGCGCTTACGATATTCGGACTGTCTTACAAGTCAATGGCAAAGAAGACAAAC
GAAAAGGAGCTTACCAGTTTGTTGCAGTGGGCATTAGTCGTGCCAGCCTCGCTCAGCTATTATATGCTTGGCTGACACCG
TTTACTGAAATTAGTACAGCAGAAGATACAACAGGCGGATACAGCGATGCTGATTTCCTTCGAATTAATCAATTTTACAT
GGAAACATCACAAAATGCAGCTATTTATCAAGCTTTATCCTTAGCTGGCAAACCAGTTACATTAGATTATAAAGGCGTAT
ATGTTTTAGACGTAAACAACGAATCTACTTTTAAAGGAACGTTACACTTAGCAGATACTGTAACAGGTGTAAATGGTAAA
CAGTTTACTAGTTCAGCAGAACTTATTGACTATGTTTCTCACCTAAAACTAGGGGATGAAGTTACGATTCAGTTTACGAG
TGATAATAAGCCTAAAAAAGGAGTTGGCCGTATTATCAAACTGAAAAATGGGAAAAATGGGATTGGCATTGCCTTGACTG
ATCATACAAGTGTCAATTCAGAAGACACAGTGATCTTTAGTACTAAAGGAGTAGGAGGACCCAGTGCTGGTCTAATGTTT
ACTCTTGATATATATGATCAAATAACTAAAGAAGATTTACGCAAGGGCCGTACAATTGCAGGTACAGGAACTATTGGCAA
GGATGGCGAAGTAGGAGATATTGGTGGTGCAGGTCTTAAAGTAGTTGCAGCAGCTGAAGCTGGTGCAGATATATTTTTTG
TTCCGAATAATCCTGTTGATAAGGAAATTAAAAAAGTTAATCCAAATGCTATAAGTAATTACGAAGAAGCCAAACGGTCA
GCCAAACGACTAAAGACCAAAATGAAGATTGTTCCTGTTACGACTGTTCAAGAGGCACTGGTTTATCTTCGCAAATAG

Domains

Predicted by InterproScan.

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (233-309)

• PDZ domain (PDZ_2) (129-192)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	68.696	100	0.687