Detailed information    

insolico Bioinformatically predicted

Overview

Name   sepM   Type   Regulator
Locus tag   ETT64_RS03045 Genome accession   NZ_CP035435
Coordinates   579689..580726 (+) Length   345 a.a.
NCBI ID   WP_047235746.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain emm64.3     
Function   processing of CSP (predicted from homology)   
Competence regulation

Genomic Context

Location: 574689..585726
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ETT64_RS03020 (ETT64_03020) - 574953..576284 (+) 1332 WP_030126384.1 dipeptidase -
  ETT64_RS03025 (ETT64_03025) arcC 576304..577254 (+) 951 WP_009880962.1 carbamate kinase -
  ETT64_RS03030 (ETT64_03030) asnA 577567..578559 (+) 993 WP_136293076.1 aspartate--ammonia ligase -
  ETT64_RS03035 (ETT64_03035) rsmD 578682..579221 (+) 540 WP_136293077.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  ETT64_RS03040 (ETT64_03040) coaD 579211..579702 (+) 492 WP_136293078.1 pantetheine-phosphate adenylyltransferase -
  ETT64_RS03045 (ETT64_03045) sepM 579689..580726 (+) 1038 WP_047235746.1 SepM family pheromone-processing serine protease Regulator
  ETT64_RS03050 (ETT64_03050) - 581140..582117 (+) 978 WP_002994809.1 LacI family DNA-binding transcriptional regulator -
  ETT64_RS03055 (ETT64_03055) - 582565..583185 (+) 621 WP_002992791.1 YutD family protein -
  ETT64_RS03060 (ETT64_03060) rlmN 583189..584268 (+) 1080 WP_002992788.1 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN -
  ETT64_RS03065 (ETT64_03065) - 584350..584976 (-) 627 WP_032465127.1 A24 family peptidase -

Sequence

Protein


Download         Length: 345 a.a.        Molecular weight: 37555.27 Da        Isoelectric Point: 9.6692

>NTDB_id=341430 ETT64_RS03045 WP_047235746.1 579689..580726(+) (sepM) [Streptococcus pyogenes strain emm64.3]
MKRLKKIKWWLVGLLALISLLLALFFPLPYYIEMPGGAYDIRTVLQVNGKEDKRKGAYQFVAVGISRASLAQLLYAWLTP
FTEISTAEDTTGGYSDADFLRINQFYMETSQNAAIYQALSLAGKPVTLDYKGVYVLDVNNESTFKGTLHLADTVTGVNGK
QFTSSAELIDYVSHLKLGDEVTVQFTSDNKPKKGVGRIIKLKNGKNGIGIALTDHTSVNSEDTVIFSTKGVGGPSAGLMF
TLDIYDQITKEDLRKGRTIAGTGTIGKDGEVGDIGGAGLKVVAAAEAGADIFFVPNNPVDKEIKKVNPNAISNYEEAKRA
AKRLKTKMKIVPITTVQEALVYLRK

Nucleotide


Download         Length: 1038 bp        

>NTDB_id=341430 ETT64_RS03045 WP_047235746.1 579689..580726(+) (sepM) [Streptococcus pyogenes strain emm64.3]
ATGAAAAGACTTAAAAAAATCAAATGGTGGTTAGTGGGTCTGCTAGCTTTAATCTCTTTGTTGCTAGCGTTATTTTTTCC
GCTACCTTATTATATTGAAATGCCTGGAGGCGCTTACGATATTCGGACTGTCTTACAAGTCAATGGCAAAGAAGACAAAC
GAAAAGGAGCTTACCAGTTTGTTGCAGTGGGCATTAGTCGTGCCAGCCTCGCTCAGCTATTATATGCTTGGCTGACACCG
TTTACTGAAATTAGTACAGCAGAAGATACAACAGGCGGATACAGCGATGCTGATTTCCTTCGAATTAATCAATTTTACAT
GGAAACATCACAAAATGCAGCTATTTATCAAGCTTTATCCTTAGCTGGAAAACCAGTTACATTAGATTATAAAGGCGTAT
ATGTTTTAGACGTAAACAACGAATCTACTTTTAAAGGAACGTTACACTTAGCAGATACTGTAACAGGTGTAAATGGTAAA
CAGTTTACTAGTTCAGCAGAACTTATTGACTATGTTTCTCACCTAAAACTAGGGGATGAAGTTACGGTTCAGTTTACGAG
TGATAATAAGCCTAAAAAAGGAGTTGGCCGTATTATCAAACTGAAAAATGGGAAAAATGGGATTGGCATTGCCTTGACTG
ATCATACAAGTGTCAATTCAGAAGACACAGTGATTTTTAGTACTAAAGGAGTAGGAGGACCTAGTGCTGGTCTAATGTTT
ACTCTTGATATATATGATCAAATAACTAAAGAAGATTTACGCAAGGGCCGTACAATTGCAGGTACAGGAACTATTGGCAA
GGATGGCGAAGTAGGAGATATTGGTGGTGCAGGTCTTAAAGTAGTTGCAGCAGCTGAAGCTGGTGCAGATATATTTTTTG
TTCCGAATAATCCTGTTGATAAGGAAATTAAAAAAGTTAATCCAAATGCTATAAGTAATTACGAAGAAGCCAAACGGGCA
GCCAAACGACTAAAGACCAAAATGAAGATTGTTCCTATTACGACTGTTCAAGAGGCACTGGTTTATCTTCGCAAATAA

Domains

Predicted by InterproScan.

Lon protease (S16) C-terminal proteolytic domain (Lon_C)

(233-309)

PDZ domain (PDZ_2)

(129-192)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sepM Streptococcus mutans UA159

68.986

100

0.69

Multiple sequence alignment