Detailed information    

insolico Bioinformatically predicted

Overview

Name   pepF   Type   Regulator
Locus tag   ETT66_RS03425 Genome accession   NZ_CP035433
Coordinates   663595..665400 (+) Length   601 a.a.
NCBI ID   WP_136286480.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain emm65     
Function   degradation of XIP; competence shut-off (predicted from homology)   
Competence regulation

Genomic Context

Location: 658595..670400
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ETT66_RS03405 (ETT66_03405) queA 659556..660584 (-) 1029 WP_002983989.1 tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA -
  ETT66_RS03410 (ETT66_03410) nagB 660786..661535 (+) 750 WP_038434150.1 glucosamine-6-phosphate deaminase -
  ETT66_RS03415 (ETT66_03415) - 661609..662325 (+) 717 WP_011528761.1 pseudouridine synthase -
  ETT66_RS03420 (ETT66_03420) - 662620..663582 (+) 963 WP_002983995.1 competence protein CoiA -
  ETT66_RS03425 (ETT66_03425) pepF 663595..665400 (+) 1806 WP_136286480.1 oligoendopeptidase F Regulator
  ETT66_RS03430 (ETT66_03430) - 665778..666974 (+) 1197 WP_002995765.1 OFA family MFS transporter -
  ETT66_RS03435 (ETT66_03435) - 667040..667747 (+) 708 WP_002989211.1 O-methyltransferase -
  ETT66_RS03440 (ETT66_03440) prsA 667810..668865 (+) 1056 WP_136286479.1 peptidylprolyl isomerase PrsA -

Sequence

Protein


Download         Length: 601 a.a.        Molecular weight: 69477.54 Da        Isoelectric Point: 4.8042

>NTDB_id=341327 ETT66_RS03425 WP_136286480.1 663595..665400(+) (pepF) [Streptococcus pyogenes strain emm65]
MTDNRSHLEEKYTWDLSTIFATDKDWEAEVSDLATEVEASKGFAGHLLDSSANLLKVTKTYLELARRVEKVYVYAHMKND
QDTTVAKYQEYQAKASGLYAKFSEVFSFYDPEVMMLHQEDYQAFLTETPELKVYNHFFDKLFQTREHVLSQAEEELLAGA
QEIFNGAEETFSILDNADIVFPIVRNDKGENVELTHGNFISLMESKDRSVRQAAYEAMYSTYEQFQHTYAKTLQTNVKVQ
NYKARVHKYDSARQAAMAANFIPEAVYDTLLETVNKHLPLLHRYLKLRQEVLGLDDLKMYDVYTPLSETDLAIGYDEALE
KAEKVLAVFGKDYADRVHRAFTERWIDVHVNKGKRSGAYSGGSYDTNAFMLLNWQDTLDNLYTLVHETGHSLHSTFTRET
QPYVYGDYSIFLAEIASTTNENIMTEALLNEVQDEKERFAILNHYLDGFRGTVFRQTQFAEFEHAIYQADQKGEVLTSEY
LNQLYADLNEKYYGLSKKDNHFIQYEWARIPHFYYNYYVYQYATGFAAASYLADKIVHGTQDDIDHYLAYLKSGNSDYPL
EVIAKAGVDMAKGDYLEAAFKVFDERLTELEVLVSKGIHKN

Nucleotide


Download         Length: 1806 bp        

>NTDB_id=341327 ETT66_RS03425 WP_136286480.1 663595..665400(+) (pepF) [Streptococcus pyogenes strain emm65]
ATGACTGATAATCGCAGCCATTTAGAAGAAAAATACACTTGGGATTTGAGCACTATTTTTGCAACAGATAAGGATTGGGA
AGCTGAAGTCAGTGACTTAGCTACTGAAGTTGAGGCATCTAAAGGTTTTGCTGGTCATTTGCTGGATTCTAGTGCTAATT
TGTTAAAGGTTACAAAAACATATTTAGAATTGGCTCGTCGTGTGGAGAAAGTCTATGTTTATGCTCACATGAAAAATGAC
CAAGACACTACTGTTGCCAAGTATCAAGAATACCAAGCTAAGGCTTCAGGCTTGTATGCAAAGTTTAGCGAAGTCTTTTC
ATTCTATGATCCAGAAGTGATGATGCTTCATCAAGAAGACTATCAGGCTTTCCTTACTGAAACCCCTGAGTTGAAAGTGT
ACAACCATTTCTTTGACAAATTATTCCAAACCCGCGAACATGTTCTTAGTCAAGCAGAAGAGGAATTATTAGCAGGAGCT
CAAGAAATTTTCAATGGTGCGGAAGAAACCTTTAGTATTCTTGATAACGCTGACATTGTTTTCCCGATAGTCAGAAATGA
TAAAGGTGAAAACGTTGAATTAACCCATGGTAACTTCATTAGCCTAATGGAATCTAAGGACCGTAGCGTTCGCCAAGCTG
CTTATGAAGCCATGTATAGTACTTATGAACAGTTCCAACATACTTACGCTAAAACCTTGCAAACCAATGTGAAAGTGCAA
AACTATAAGGCGCGTGTTCATAAATACGATTCAGCTCGTCAGGCTGCCATGGCTGCTAACTTTATTCCTGAAGCTGTTTA
CGATACCTTGTTAGAAACGGTTAATAAACATTTGCCACTCTTACACCGTTATTTGAAATTGCGTCAAGAGGTTCTTGGTT
TAGACGATTTGAAGATGTATGATGTTTACACACCACTATCTGAAACAGATCTAGCCATTGGTTATGATGAGGCTTTGGAA
AAGGCTGAGAAGGTTTTGGCTGTTTTTGGTAAAGATTACGCAGATCGTGTGCATCGTGCTTTTACCGAACGTTGGATTGA
TGTTCACGTCAATAAAGGGAAGCGCTCAGGAGCTTATTCAGGTGGTTCCTATGATACCAATGCCTTCATGCTATTAAACT
GGCAAGATACCTTAGACAATCTATACACTTTAGTTCATGAAACTGGGCACAGTTTGCATTCTACTTTCACTCGTGAAACA
CAGCCTTATGTGTATGGAGATTACAGTATTTTCTTGGCAGAAATTGCATCCACAACGAATGAAAACATCATGACAGAAGC
TCTCTTAAATGAGGTGCAAGATGAGAAAGAACGCTTTGCCATTTTAAACCATTACCTCGATGGTTTCCGTGGAACAGTTT
TCCGTCAAACCCAATTTGCTGAGTTTGAACATGCCATTTATCAAGCTGATCAAAAAGGAGAAGTGTTAACAAGTGAATAC
CTTAACCAGCTATACGCTGATTTAAATGAAAAATATTATGGTTTAAGTAAAAAAGATAATCATTTTATTCAGTATGAATG
GGCACGTATTCCTCATTTCTATTACAATTATTATGTTTACCAATATGCAACAGGTTTTGCAGCTGCAAGCTATTTAGCGG
ATAAGATTGTGCATGGCACACAAGACGATATCGATCATTACTTGGCCTACCTCAAGTCAGGAAATTCTGATTACCCACTT
GAAGTGATTGCTAAAGCAGGCGTTGATATGGCAAAAGGTGATTATTTGGAAGCCGCCTTTAAAGTCTTTGACGAACGTCT
AACAGAACTTGAAGTACTCGTGTCCAAAGGCATACACAAAAACTAA

Domains

Predicted by InterproScan.

Peptidase family M3 (Peptidase_M3)

(202-581)

Oligopeptidase F (Peptidase_M3_N)

(112-181)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pepF Streptococcus salivarius strain HSISS4

70.618

99.667

0.704

Multiple sequence alignment