Detailed information    

insolico Bioinformatically predicted

Overview

Name   sepM   Type   Regulator
Locus tag   ETT66_RS03070 Genome accession   NZ_CP035433
Coordinates   590012..591049 (+) Length   345 a.a.
NCBI ID   WP_136286506.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain emm65     
Function   processing of CSP (predicted from homology)   
Competence regulation

Genomic Context

Location: 585012..596049
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ETT66_RS03045 (ETT66_03045) - 585276..586607 (+) 1332 WP_136270531.1 dipeptidase -
  ETT66_RS03050 (ETT66_03050) arcC 586627..587577 (+) 951 WP_109828594.1 carbamate kinase -
  ETT66_RS03055 (ETT66_03055) asnA 587890..588882 (+) 993 WP_136286315.1 aspartate--ammonia ligase -
  ETT66_RS03060 (ETT66_03060) rsmD 589005..589544 (+) 540 WP_002983819.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  ETT66_RS03065 (ETT66_03065) coaD 589534..590025 (+) 492 WP_014407698.1 pantetheine-phosphate adenylyltransferase -
  ETT66_RS03070 (ETT66_03070) sepM 590012..591049 (+) 1038 WP_136286506.1 SepM family pheromone-processing serine protease Regulator
  ETT66_RS03075 (ETT66_03075) - 591463..592440 (+) 978 WP_002994809.1 LacI family DNA-binding transcriptional regulator -
  ETT66_RS03080 (ETT66_03080) - 592888..593508 (+) 621 WP_038434166.1 YutD family protein -
  ETT66_RS03085 (ETT66_03085) rlmN 593512..594591 (+) 1080 WP_002992788.1 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN -
  ETT66_RS03090 (ETT66_03090) - 594673..595299 (-) 627 WP_136286504.1 A24 family peptidase -

Sequence

Protein


Download         Length: 345 a.a.        Molecular weight: 37527.22 Da        Isoelectric Point: 9.6692

>NTDB_id=341324 ETT66_RS03070 WP_136286506.1 590012..591049(+) (sepM) [Streptococcus pyogenes strain emm65]
MKRLKKIKWWLVGLLALVSLLLALFFPLPYYIEMPGGAYDIRTVLQVNGKEDKRKGAYQFVAVGISRASLAQLLYAWLTP
FTEISTAEDTTGGYSDADFLRINQFYMETSQNAAIYQALSLAGKPVTLDYKGVYVLDVNNESTFKGTLHLADTVTGVNGK
QFTSSAELIDYVSHLKLGDEVTVQFTSDNKPKKGVGRIIKLKNGKNGIGIALTDHTSVNSEDTVIFSTKGVGGPSAGLMF
TLDIYDQITKEDLRKGRTIAGTGTIGKDGEVGDIGGAGLKVVAAAEAGADIFFVPNNPVDKEIKKVNPNAISNYEEAKRA
AKRLKTKMKIVPVTTVQEALVYLRK

Nucleotide


Download         Length: 1038 bp        

>NTDB_id=341324 ETT66_RS03070 WP_136286506.1 590012..591049(+) (sepM) [Streptococcus pyogenes strain emm65]
ATGAAAAGACTTAAAAAAATCAAATGGTGGTTAGTGGGTCTGCTAGCTTTAGTCTCTTTGTTGCTAGCGTTATTTTTTCC
GCTACCTTATTATATTGAAATGCCTGGAGGCGCTTACGATATTCGGACTGTCTTACAAGTCAATGGCAAAGAAGACAAAC
GAAAAGGAGCTTACCAGTTTGTTGCAGTGGGCATTAGTCGTGCCAGCCTCGCTCAGCTATTATATGCTTGGCTGACACCG
TTTACTGAAATTAGTACAGCAGAAGATACAACAGGCGGATACAGCGATGCTGATTTCCTTCGAATTAATCAATTTTACAT
GGAAACATCACAAAATGCAGCTATTTATCAAGCTTTATCCTTAGCTGGAAAACCAGTTACATTAGATTATAAAGGCGTAT
ATGTTTTAGACGTAAACAACGAATCTACTTTTAAAGGAACGCTACACTTAGCAGATACTGTAACAGGTGTAAATGGTAAA
CAGTTTACTAGTTCAGCAGAACTTATTGACTATGTTTCTCACCTAAAACTAGGGGATGAAGTTACGGTTCAGTTTACGAG
TGATAATAAGCCTAAAAAAGGAGTTGGCCGTATTATCAAACTGAAAAATGGGAAAAATGGGATTGGCATTGCCTTGACTG
ATCATACAAGTGTCAATTCAGAAGACACAGTGATCTTTAGTACTAAAGGAGTAGGAGGACCTAGTGCTGGTCTAATGTTT
ACTCTTGATATATATGATCAAATAACTAAAGAAGATTTACGCAAGGGCCGTACAATTGCAGGTACAGGAACTATTGGCAA
GGATGGCGAAGTAGGAGATATTGGTGGTGCAGGTCTTAAAGTAGTTGCAGCAGCTGAAGCTGGTGCAGATATATTTTTTG
TTCCGAATAATCCTGTTGATAAGGAAATTAAAAAAGTTAATCCAAATGCTATAAGTAATTACGAAGAAGCCAAACGGGCA
GCCAAACGACTAAAGACCAAAATGAAGATTGTTCCTGTTACGACTGTTCAAGAGGCACTGGTTTATCTTCGCAAATAA

Domains

Predicted by InterproScan.

Lon protease (S16) C-terminal proteolytic domain (Lon_C)

(233-309)

PDZ domain (PDZ_2)

(129-192)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sepM Streptococcus mutans UA159

68.986

100

0.69

Multiple sequence alignment