Detailed information NTG0341292

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: ETT67_RS08620
• Genome accession: NZ_CP035432
• Coordinates: 1696591..1699035 (-)
• Length: 814 a.a.
• NCBI ID: WP_053308657.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain emm11
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 1691591..1704035

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ETT67_RS08595 (ETT67_08585)	-	1691768..1693264 (+)	1497	WP_136019704.1	C69 family dipeptidase	-
ETT67_RS09430 (ETT67_08590)	-	1693558..1693939 (+)	382	Protein_1600	NUDIX domain-containing protein	-
ETT67_RS08605 (ETT67_08595)	-	1693925..1694245 (-)	321	Protein_1601	helix-turn-helix domain-containing protein	-
ETT67_RS08610 (ETT67_08600)	groL	1694456..1696087 (-)	1632	WP_136019703.1	chaperonin GroEL	-
ETT67_RS08615 (ETT67_08605)	groES	1696123..1696413 (-)	291	WP_002991292.1	co-chaperone GroES	-
ETT67_RS08620 (ETT67_08610)	clpC	1696591..1699035 (-)	2445	WP_053308657.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
ETT67_RS08625 (ETT67_08615)	-	1699035..1699496 (-)	462	WP_002982312.1	CtsR family transcriptional regulator	-
ETT67_RS08630 (ETT67_08620)	-	1699692..1699895 (-)	204	WP_002991299.1	cold-shock protein	-
ETT67_RS08640 (ETT67_08630)	ahpC	1700891..1701451 (+)	561	WP_002982304.1	alkyl hydroperoxide reductase subunit C	-
ETT67_RS08645 (ETT67_08635)	ahpF	1701472..1703004 (+)	1533	WP_002982300.1	alkyl hydroperoxide reductase subunit F	-

Sequence

Protein

• Length: 814 a.a.
• Molecular weight: 90642.35 Da
• Isoelectric Point: 6.9601

>NTDB_id=341292 ETT67_RS08620 WP_053308657.1 1696591..1699035(-) (clpC) [Streptococcus pyogenes strain emm11]
MIMYSTKMQDIFRQAQFQAARFDSHCLETWHVLLAMVAVDNSLANMILSEYDAQVAIEEYEAAAILAMGKTPKEQLSRVD
FRPQSKTLTNLLAFAQAISQITRDQEVGSEHVLFAILLNPDIMASRLLEIAGYQIKDNGNGQPRLADLRKAIERHAGYSK
EMIKAIHELRKPKKTKTQGTFSDMMKPPSTAGELSDFTRDLTEMARQGLLESVIGRDQEVSRMIQVLSRKTKNNPVLVGD
AGVGKTALAYGLAQRIANGAIPYELKEMRVLELDMMSVVAGTRFRGDFEERMNQIIDDIEADGQIILFVDELHTIMGSGS
GIDSTLDAANILKPALSRGTLHMVGATTQEEYQKHIEKDAALSRRFAKILIEEPNTEDAYQILMGLKLSYETYHNVSISN
EAVKTAVKMAHRYLTSKNLPDSAIDLLDEASAAVQNMVKKSAPETLTPIDQALINGDMKKVSRLLAKEAKGQMRKPTPVT
EDDILATLSKLSGIPLEKLTQADSKKYLNLEKELHKRVIGQDAAVTAISRAIRRNQSGIRTGKRPIGSFMFLGPTGVGKT
ELAKALAEVLFDDDAALIRFDMSEYMEKFAASRLNGAPPGYVGYDEGGELTQKVRNKPYSVLLFDEVEKAHPDIFNVLLQ
VLDDGILTDSRGRKVDFSNTIIIMTSNLGATALRDDKTVGFGVKGIHQDHQAMEKRILEELRKTYRPEFINRIDEKVVFH
SLTQDNMRDVVKIMVQPLITTLAEKGITLKIQPLALKHLSEVGYDEHMGARPLRRTLQTEIEDKLSELILSRELTSGHTL
KIGLSHGKLTFHIA

Nucleotide

• Length: 2445 bp

>NTDB_id=341292 ETT67_RS08620 WP_053308657.1 1696591..1699035(-) (clpC) [Streptococcus pyogenes strain emm11]
ATGATTATGTATTCAACGAAGATGCAAGACATTTTTAGACAGGCGCAGTTCCAAGCTGCTCGCTTTGATAGCCATTGCCT
GGAAACTTGGCATGTTTTGTTAGCTATGGTAGCTGTAGATAATTCTTTAGCAAATATGATTTTAAGTGAATATGATGCCC
AAGTCGCCATAGAAGAATATGAAGCTGCAGCTATTTTAGCCATGGGCAAAACCCCTAAAGAACAGTTGTCTCGTGTAGAC
TTCAGACCTCAATCTAAAACTTTGACTAACTTGTTAGCTTTTGCGCAGGCTATTAGCCAAATCACTAGGGATCAAGAAGT
CGGCTCTGAGCATGTCTTATTTGCTATTTTATTGAATCCAGATATTATGGCGAGTCGTTTGTTAGAAATAGCTGGCTATC
AGATAAAAGATAACGGCAATGGGCAGCCGCGATTAGCTGACTTGCGAAAAGCAATAGAACGTCATGCAGGTTACAGTAAG
GAAATGATCAAGGCTATTCACGAACTACGTAAGCCTAAAAAAACGAAAACACAAGGGACCTTTTCAGATATGATGAAGCC
ACCAAGTACAGCTGGTGAGTTGAGTGATTTCACAAGAGATTTGACTGAAATGGCAAGACAAGGTTTGTTAGAATCGGTGA
TTGGACGTGACCAAGAAGTATCTCGTATGATTCAGGTACTAAGTCGTAAAACGAAAAACAATCCTGTCTTGGTGGGTGAT
GCAGGTGTTGGTAAAACTGCGCTTGCTTATGGCCTTGCTCAACGGATTGCAAATGGCGCTATTCCTTATGAACTTAAGGA
GATGCGTGTCCTAGAATTAGACATGATGAGTGTGGTAGCAGGAACCCGTTTTCGTGGGGATTTTGAAGAGCGCATGAATC
AAATCATTGATGATATTGAAGCTGATGGTCAGATTATTCTTTTTGTTGATGAACTACATACTATTATGGGTTCTGGCAGT
GGTATTGACAGTACACTTGATGCGGCTAACATTTTAAAACCAGCATTATCGCGCGGCACTCTTCATATGGTTGGAGCAAC
AACTCAAGAAGAATACCAAAAACATATTGAAAAAGATGCAGCTCTTTCGCGTCGTTTTGCTAAAATATTAATTGAAGAAC
CTAATACAGAAGATGCTTATCAGATTTTGATGGGCCTAAAATTATCTTATGAGACCTACCATAATGTCTCGATATCAAAT
GAGGCAGTTAAAACAGCTGTAAAAATGGCACACCGTTATTTAACCAGTAAAAATCTCCCTGATTCAGCTATCGATTTATT
AGATGAAGCTAGTGCTGCTGTGCAAAACATGGTGAAAAAATCAGCACCTGAGACTTTAACACCAATAGACCAAGCTCTTA
TCAATGGTGATATGAAAAAAGTATCTCGCCTCTTAGCTAAAGAAGCAAAAGGTCAGATGAGAAAACCAACACCGGTGACA
GAAGATGATATTTTGGCAACCTTGAGTAAGTTATCGGGAATTCCACTTGAAAAACTGACGCAAGCTGATAGTAAAAAATA
CCTCAATTTAGAAAAAGAACTGCATAAGCGTGTGATTGGTCAGGATGCTGCTGTTACGGCTATTTCAAGAGCCATTCGTC
GCAATCAGTCAGGTATTCGAACAGGAAAACGTCCTATTGGATCATTTATGTTTCTTGGCCCAACAGGAGTAGGTAAGACA
GAACTAGCAAAGGCCCTTGCAGAAGTTCTCTTTGATGATGACGCAGCGCTTATTCGTTTTGATATGTCTGAGTACATGGA
AAAATTCGCAGCGTCTAGGCTTAATGGAGCACCTCCTGGTTATGTCGGCTATGATGAAGGAGGTGAACTGACACAGAAAG
TTAGAAATAAACCTTATTCAGTCTTGCTTTTTGATGAAGTGGAAAAAGCACATCCTGATATTTTTAACGTCCTCCTTCAA
GTATTAGATGATGGTATATTGACTGATAGTCGTGGGCGTAAGGTCGATTTTTCAAATACTATTATTATCATGACCAGCAA
TCTTGGCGCAACAGCCCTGCGCGATGATAAAACGGTCGGTTTTGGGGTCAAAGGCATTCACCAAGACCATCAAGCTATGG
AGAAACGTATTTTAGAAGAATTAAGAAAAACTTACCGCCCAGAATTTATCAATCGTATTGATGAAAAAGTGGTCTTTCAT
AGTCTGACCCAAGATAACATGCGTGATGTGGTTAAAATCATGGTACAGCCCCTGATTACTACATTGGCAGAAAAAGGTAT
TACCCTTAAAATTCAGCCTTTGGCCTTGAAACATTTGTCCGAGGTCGGCTATGATGAGCATATGGGGGCAAGACCATTAC
GTCGAACGCTGCAAACTGAGATAGAAGATAAGCTATCAGAGCTTATTCTTTCTCGAGAATTGACAAGTGGGCATACGCTA
AAAATTGGATTATCACATGGCAAATTAACGTTTCACATAGCTTAA

Domains

Predicted by InterproScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (722-801)

• ATPase family associated with various cellular activities (AAA) (AAA) (236-368)

• AAA lid domain (AAA_lid_9) (376-459)

• AAA domain (Cdc48 subfamily) (AAA_2) (544-715)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (95-130)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Streptococcus mutans UA159	75.031	99.877	0.749
clpC	Streptococcus thermophilus LMG 18311	71.201	100	0.714
clpC	Streptococcus thermophilus LMD-9	71.078	100	0.713
clpC	Streptococcus pneumoniae TIGR4	65.848	100	0.658
clpC	Streptococcus pneumoniae Rx1	65.848	100	0.658
clpC	Streptococcus pneumoniae D39	65.848	100	0.658
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	47.733	100	0.491
clpC	Bacillus subtilis subsp. subtilis str. 168	42.206	100	0.432