Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   ETT67_RS01600 Genome accession   NZ_CP035432
Coordinates   293839..294525 (+) Length   228 a.a.
NCBI ID   WP_002991052.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain emm11     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 288839..299525
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ETT67_RS01570 (ETT67_01570) rsmG 289116..289829 (-) 714 WP_023078972.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  ETT67_RS01580 (ETT67_01580) - 289995..291128 (-) 1134 WP_115224530.1 ISAs1-like element IS1548 family transposase -
  ETT67_RS01585 (ETT67_01585) - 291305..291862 (+) 558 WP_002985956.1 LemA family protein -
  ETT67_RS01590 (ETT67_01590) htpX 291909..292805 (+) 897 WP_002985953.1 zinc metalloprotease HtpX -
  ETT67_RS01595 (ETT67_01595) - 293039..293572 (+) 534 WP_011054200.1 DUF177 domain-containing protein -
  ETT67_RS01600 (ETT67_01600) covR 293839..294525 (+) 687 WP_002991052.1 two-component system response regulator CovR Regulator
  ETT67_RS01605 (ETT67_01605) covS 294531..296033 (+) 1503 WP_002991036.1 two-component system sensor histidine kinase CovS -
  ETT67_RS01610 (ETT67_01610) nrdR 296247..296741 (+) 495 WP_002985941.1 transcriptional regulator NrdR -
  ETT67_RS01615 (ETT67_01615) - 296725..297900 (+) 1176 WP_009880401.1 replication initiation and membrane attachment family protein -
  ETT67_RS01620 (ETT67_01620) dnaI 297901..298803 (+) 903 WP_023078968.1 primosomal protein DnaI -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 26618.70 Da        Isoelectric Point: 4.6586

>NTDB_id=341263 ETT67_RS01600 WP_002991052.1 293839..294525(+) (covR) [Streptococcus pyogenes strain emm11]
MTKKILIIEDEKNLARFVSLELQHEGYEVIVEVNGREGLETALEKEFDLILLDLMLPEMDGFEVTRRLQTEKTTYIMMMT
ARDSIMDVVAGLDRGADDYIVKPFAIEELLARIRAIFRRQDIESEKKVPSQGIYRDLVLNPQNRSVNRGDDEISLTKREY
DLLNILMTNMNRVMTREELLSNVWKYDEAVETNVVDVYIRYLRGKIDIPGKESYIQTVRGMGYVIREK

Nucleotide


Download         Length: 687 bp        

>NTDB_id=341263 ETT67_RS01600 WP_002991052.1 293839..294525(+) (covR) [Streptococcus pyogenes strain emm11]
ATGACAAAGAAAATTTTAATTATTGAAGATGAAAAGAATCTGGCTAGATTCGTTTCTCTTGAGCTGCAACATGAGGGTTA
TGAAGTCATTGTTGAGGTCAATGGTCGCGAAGGGTTAGAAACTGCTTTGGAAAAAGAGTTTGATTTAATCCTGCTTGACT
TAATGTTACCAGAGATGGATGGTTTTGAAGTGACCCGTCGTTTGCAAACCGAAAAAACAACGTATATCATGATGATGACT
GCGCGTGATTCTATTATGGATGTGGTTGCAGGTTTAGACCGCGGTGCAGACGACTATATTGTTAAACCGTTTGCCATTGA
AGAACTACTTGCCCGTATTCGTGCTATTTTCCGCCGTCAAGATATTGAATCTGAGAAGAAAGTGCCTAGTCAAGGCATTT
ATCGAGATCTAGTTTTAAATCCACAAAACCGTTCAGTTAATCGTGGCGACGATGAGATTTCTCTCACTAAACGTGAATAT
GATTTGCTTAATATTTTGATGACTAACATGAATCGTGTCATGACACGTGAAGAATTATTGTCAAATGTTTGGAAATATGA
TGAAGCCGTTGAGACTAATGTTGTAGATGTCTATATTCGTTATCTCCGCGGCAAAATTGACATTCCAGGCAAGGAATCTT
ATATCCAAACAGTGCGTGGCATGGGATACGTTATTCGTGAGAAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(151-224)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

82.096

100

0.825
  covR Lactococcus lactis subsp. lactis strain DGCC12653

66.96

99.561

0.667
  vicR Streptococcus mutans UA159

43.966

100

0.447
  micA Streptococcus pneumoniae Cp1015

42.174

100

0.425

Multiple sequence alignment