Detailed information NTG0341231

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: ETT68_RS06210
• Genome accession: NZ_CP035431
• Coordinates: 1223430..1224467 (-)
• Length: 345 a.a.
• NCBI ID: WP_111684731.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain emm105
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1218430..1229467

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ETT68_RS06185 (ETT68_06180)	-	1218434..1218961 (-)	528	WP_002983837.1	Dps family protein	-
ETT68_RS06190 (ETT68_06185)	-	1219189..1219815 (+)	627	WP_002983834.1	A24 family peptidase	-
ETT68_RS06195 (ETT68_06190)	rlmN	1219897..1220976 (-)	1080	WP_109991722.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
ETT68_RS06200 (ETT68_06195)	-	1220980..1221600 (-)	621	WP_002992791.1	YutD family protein	-
ETT68_RS06205 (ETT68_06200)	-	1222048..1223025 (-)	978	WP_109991723.1	LacI family DNA-binding transcriptional regulator	-
ETT68_RS06210 (ETT68_06205)	sepM	1223430..1224467 (-)	1038	WP_111684731.1	SepM family pheromone-processing serine protease	Regulator
ETT68_RS06215 (ETT68_06210)	coaD	1224454..1224945 (-)	492	WP_002983821.1	pantetheine-phosphate adenylyltransferase	-
ETT68_RS06220 (ETT68_06215)	rsmD	1224935..1225474 (-)	540	WP_002983819.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
ETT68_RS06225 (ETT68_06220)	asnA	1225597..1226589 (-)	993	WP_023611792.1	aspartate--ammonia ligase	-
ETT68_RS06230 (ETT68_06225)	arcC	1226902..1227852 (-)	951	WP_010922501.1	carbamate kinase	-
ETT68_RS06235 (ETT68_06230)	-	1227872..1229203 (-)	1332	WP_032460502.1	dipeptidase	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37571.27 Da
• Isoelectric Point: 9.6692

>NTDB_id=341231 ETT68_RS06210 WP_111684731.1 1223430..1224467(-) (sepM) [Streptococcus pyogenes strain emm105]
MKRLKKIKWWLVGLLALISLLLALFFPLPYYIEMPGGAYDIRTVLQVNGKEDKRKGAYQFVAVGISRASLAQLLYAWLTP
FTEISTAEDTTGGYSDADFLRINQFYMETSQNAAIYQALSLAGKPVTLDYKGVYVLDVNNESTFKGTLHLADTVTGVNGK
QFTSSAELIDYVSHLKLGDEVTIQFTSDNKPKKGVGRIIKLKNGKNGIGIALTDHTSVNSEDTVIFSTKGVGGPSAGLMF
TLDIYDQITKEDLRKGRTIAGTGTIGKDGEVGDIGGAGLKVVAAAEAGADIFFVPNNPVDKEIKKVNPNAISNYEEAKRS
AKRLKTKMKIVPVTTVQEALVYLRK

Nucleotide

• Length: 1038 bp

>NTDB_id=341231 ETT68_RS06210 WP_111684731.1 1223430..1224467(-) (sepM) [Streptococcus pyogenes strain emm105]
ATGAAAAGACTTAAAAAAATCAAATGGTGGTTAGTGGGTCTGCTAGCTTTAATCTCTTTGTTGCTAGCGTTATTTTTTCC
GCTACCTTATTATATTGAAATGCCTGGAGGCGCTTACGATATTCGGACTGTCTTACAAGTCAATGGCAAAGAAGACAAAC
GAAAAGGAGCTTACCAGTTTGTTGCAGTGGGCATTAGTCGTGCCAGCCTCGCTCAGCTATTATATGCTTGGCTGACACCG
TTTACTGAAATTAGTACAGCAGAAGATACAACAGGCGGATACAGCGATGCTGATTTCCTTCGAATTAATCAATTTTACAT
GGAAACATCACAAAATGCAGCTATTTATCAAGCTTTATCCTTAGCTGGCAAACCAGTTACATTAGATTATAAAGGCGTAT
ATGTTTTAGACGTAAACAACGAATCTACTTTTAAAGGAACGTTACACTTAGCAGATACTGTAACAGGTGTAAATGGTAAA
CAGTTTACTAGTTCAGCAGAACTTATTGACTATGTTTCTCACCTAAAACTAGGGGATGAAGTTACGATTCAGTTTACGAG
TGATAATAAGCCTAAAAAAGGAGTTGGCCGTATTATCAAACTGAAAAATGGGAAAAATGGGATTGGCATTGCCTTGACTG
ATCATACAAGTGTCAATTCAGAAGACACAGTGATCTTTAGTACTAAAGGAGTAGGAGGACCCAGTGCTGGTCTAATGTTT
ACTCTTGATATATATGATCAAATAACTAAAGAAGATTTACGCAAGGGCCGTACAATTGCAGGTACAGGAACTATTGGCAA
GGATGGCGAAGTAGGAGATATTGGTGGTGCAGGTCTTAAAGTAGTTGCAGCAGCTGAAGCTGGTGCAGATATATTTTTTG
TTCCGAATAATCCTGTTGATAAGGAAATTAAAAAAGTTAATCCAAATGCTATAAGTAATTACGAAGAAGCCAAACGGTCA
GCCAAACGACTAAAGACCAAAATGAAGATTGTTCCTGTTACGACTGTTCAAGAGGCACTGGTTTATCTTCGCAAATAG

Domains

Predicted by InterproScan.

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (233-309)

• PDZ domain (PDZ_2) (129-192)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	68.696	100	0.687