Detailed information
Bioinformatically predicted
Overview
| Name | radA | Type | Machinery gene |
| Locus tag | ETT69_RS01440 | Genome accession | NZ_CP035430 |
| Coordinates | 246454..247815 (+) | Length | 453 a.a. |
| NCBI ID | WP_002986109.1 | Uniprot ID | A0A4Q1R665 |
| Organism | Streptococcus pyogenes strain emm55 | ||
| Function | homologous recombination (predicted from homology) Homologous recombination |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 194328..246373 | 246454..247815 | flank | 81 |
Gene organization within MGE regions
Location: 194328..247815
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| ETT69_RS01115 (ETT69_01115) | - | 194328..195560 (-) | 1233 | WP_136019349.1 | transglutaminase domain-containing protein | - |
| ETT69_RS09810 | - | 195936..197078 (-) | 1143 | WP_180383156.1 | site-specific integrase | - |
| ETT69_RS01130 (ETT69_01130) | - | 197205..197738 (-) | 534 | WP_003055464.1 | hypothetical protein | - |
| ETT69_RS01135 (ETT69_01135) | - | 197750..198130 (-) | 381 | WP_002986288.1 | ImmA/IrrE family metallo-endopeptidase | - |
| ETT69_RS01140 (ETT69_01140) | - | 198140..198487 (-) | 348 | WP_003055470.1 | helix-turn-helix domain-containing protein | - |
| ETT69_RS01145 (ETT69_01145) | - | 198777..198941 (+) | 165 | WP_003057272.1 | hypothetical protein | - |
| ETT69_RS01150 (ETT69_01150) | - | 198984..199187 (+) | 204 | WP_136019350.1 | XRE family transcriptional regulator | - |
| ETT69_RS10040 | - | 199189..199323 (+) | 135 | WP_003057293.1 | hypothetical protein | - |
| ETT69_RS01155 (ETT69_01155) | - | 199320..199688 (+) | 369 | WP_003057274.1 | hypothetical protein | - |
| ETT69_RS01160 (ETT69_01160) | - | 199728..199988 (+) | 261 | WP_115250271.1 | hypothetical protein | - |
| ETT69_RS01165 (ETT69_01165) | - | 200007..200195 (+) | 189 | WP_071127087.1 | hypothetical protein | - |
| ETT69_RS01170 (ETT69_01170) | dnaB | 200182..201522 (+) | 1341 | WP_136019351.1 | replicative DNA helicase | - |
| ETT69_RS01175 (ETT69_01175) | - | 201515..202279 (+) | 765 | WP_136019352.1 | conserved phage C-terminal domain-containing protein | - |
| ETT69_RS01180 (ETT69_01180) | - | 202279..203088 (+) | 810 | WP_136019353.1 | ATP-binding protein | - |
| ETT69_RS01185 (ETT69_01185) | - | 203088..203315 (+) | 228 | WP_136019354.1 | hypothetical protein | - |
| ETT69_RS01190 (ETT69_01190) | - | 203305..203505 (+) | 201 | WP_181876623.1 | hypothetical protein | - |
| ETT69_RS01195 (ETT69_01195) | - | 203505..203774 (+) | 270 | WP_210725281.1 | hypothetical protein | - |
| ETT69_RS01200 (ETT69_01200) | - | 203777..204112 (+) | 336 | WP_011054813.1 | hypothetical protein | - |
| ETT69_RS01205 (ETT69_01205) | - | 204115..204597 (+) | 483 | WP_136019356.1 | class I SAM-dependent methyltransferase | - |
| ETT69_RS01210 (ETT69_01210) | - | 204587..205351 (+) | 765 | WP_136019357.1 | site-specific DNA-methyltransferase | - |
| ETT69_RS01215 (ETT69_01215) | - | 205399..205728 (+) | 330 | WP_136019358.1 | DUF1642 domain-containing protein | - |
| ETT69_RS01220 (ETT69_01220) | - | 205750..206088 (+) | 339 | WP_000776643.1 | helix-turn-helix domain-containing protein | - |
| ETT69_RS09700 | - | 206233..206382 (+) | 150 | WP_168389132.1 | hypothetical protein | - |
| ETT69_RS01225 (ETT69_01225) | - | 206351..206551 (+) | 201 | WP_003057287.1 | hypothetical protein | - |
| ETT69_RS01230 (ETT69_01230) | - | 206575..206994 (+) | 420 | WP_002986196.1 | DUF1492 domain-containing protein | - |
| ETT69_RS01235 (ETT69_01235) | - | 207089..207652 (+) | 564 | WP_032467304.1 | site-specific integrase | - |
| ETT69_RS01240 (ETT69_01240) | - | 207824..208117 (+) | 294 | WP_136019359.1 | hypothetical protein | - |
| ETT69_RS01245 (ETT69_01245) | - | 208114..208443 (+) | 330 | WP_136019360.1 | HNH endonuclease signature motif containing protein | - |
| ETT69_RS01250 (ETT69_01250) | - | 208565..208912 (+) | 348 | WP_002986187.1 | hypothetical protein | - |
| ETT69_RS01255 (ETT69_01255) | - | 208893..210551 (+) | 1659 | WP_002986185.1 | terminase TerL endonuclease subunit | - |
| ETT69_RS01260 (ETT69_01260) | - | 210749..211984 (+) | 1236 | WP_003057282.1 | phage portal protein | - |
| ETT69_RS01265 (ETT69_01265) | - | 211988..212704 (+) | 717 | WP_002986180.1 | head maturation protease, ClpP-related | - |
| ETT69_RS01270 (ETT69_01270) | - | 212740..213933 (+) | 1194 | WP_002986177.1 | phage major capsid protein | - |
| ETT69_RS01275 (ETT69_01275) | - | 213948..214235 (+) | 288 | WP_002986176.1 | hypothetical protein | - |
| ETT69_RS01280 (ETT69_01280) | - | 214255..214548 (+) | 294 | WP_003057269.1 | phage gp6-like head-tail connector protein | - |
| ETT69_RS01285 (ETT69_01285) | - | 214550..214927 (+) | 378 | WP_227868726.1 | phage head-tail adapter protein | - |
| ETT69_RS01290 (ETT69_01290) | - | 214899..215270 (+) | 372 | WP_002986170.1 | hypothetical protein | - |
| ETT69_RS01295 (ETT69_01295) | - | 215279..215701 (+) | 423 | WP_002986168.1 | hypothetical protein | - |
| ETT69_RS01300 (ETT69_01300) | - | 215712..216299 (+) | 588 | WP_136019362.1 | phage tail protein | - |
| ETT69_RS01305 (ETT69_01305) | - | 216320..216691 (+) | 372 | WP_002986164.1 | hypothetical protein | - |
| ETT69_RS09705 | - | 216727..216885 (+) | 159 | WP_002986162.1 | hypothetical protein | - |
| ETT69_RS01310 (ETT69_01310) | - | 216959..220360 (+) | 3402 | WP_136019363.1 | phage tail tape measure protein | - |
| ETT69_RS01315 (ETT69_01315) | - | 220357..221067 (+) | 711 | WP_037587950.1 | phage tail domain-containing protein | - |
| ETT69_RS01320 (ETT69_01320) | - | 221064..223118 (+) | 2055 | WP_136019364.1 | phage tail spike protein | - |
| ETT69_RS01325 (ETT69_01325) | - | 223115..224059 (+) | 945 | WP_227868727.1 | hyaluronoglucosaminidase | - |
| ETT69_RS01330 (ETT69_01330) | - | 224062..224694 (+) | 633 | WP_136019365.1 | hypothetical protein | - |
| ETT69_RS01335 (ETT69_01335) | - | 224705..226615 (+) | 1911 | WP_136019366.1 | gp58-like family protein | - |
| ETT69_RS01340 (ETT69_01340) | - | 226624..226785 (+) | 162 | WP_002988795.1 | hypothetical protein | - |
| ETT69_RS01345 (ETT69_01345) | - | 226788..227399 (+) | 612 | WP_065358780.1 | hypothetical protein | - |
| ETT69_RS01350 (ETT69_01350) | - | 227410..227709 (+) | 300 | WP_002988799.1 | hypothetical protein | - |
| ETT69_RS01355 (ETT69_01355) | - | 227706..227891 (+) | 186 | WP_002988802.1 | holin | - |
| ETT69_RS01360 (ETT69_01360) | - | 228008..228760 (+) | 753 | WP_136019367.1 | CHAP domain-containing protein | - |
| ETT69_RS01365 (ETT69_01365) | - | 229052..230011 (+) | 960 | WP_065358778.1 | Abi family protein | - |
| ETT69_RS01370 (ETT69_01370) | sda1 | 230328..231509 (-) | 1182 | WP_136019368.1 | streptodornase Sda1 | - |
| ETT69_RS01375 (ETT69_01375) | prx | 231748..231930 (+) | 183 | WP_136019369.1 | Paratox | Regulator |
| ETT69_RS01380 (ETT69_01380) | - | 232065..232256 (-) | 192 | WP_002986145.1 | helix-turn-helix transcriptional regulator | - |
| ETT69_RS01385 (ETT69_01385) | speG | 232928..233632 (+) | 705 | WP_136019370.1 | streptococcal pyrogenic exotoxin SpeG | - |
| ETT69_RS01390 (ETT69_01390) | - | 234088..235437 (+) | 1350 | WP_136019371.1 | glucose-6-phosphate isomerase | - |
| ETT69_RS01395 (ETT69_01395) | - | 235785..237293 (-) | 1509 | WP_136019372.1 | helix-turn-helix domain-containing protein | - |
| ETT69_RS01400 (ETT69_01400) | - | 237981..238652 (+) | 672 | WP_136019373.1 | rhomboid family intramembrane serine protease | - |
| ETT69_RS01405 (ETT69_01405) | galU | 238751..239650 (-) | 900 | WP_002986125.1 | UTP--glucose-1-phosphate uridylyltransferase GalU | - |
| ETT69_RS01410 (ETT69_01410) | - | 239683..240699 (-) | 1017 | WP_002986123.1 | NAD(P)H-dependent glycerol-3-phosphate dehydrogenase | - |
| ETT69_RS01415 (ETT69_01415) | - | 240997..241446 (+) | 450 | WP_002986120.1 | MarR family winged helix-turn-helix transcriptional regulator | - |
| ETT69_RS01420 (ETT69_01420) | - | 241439..243145 (+) | 1707 | WP_011284484.1 | ABC transporter ATP-binding protein | - |
| ETT69_RS01425 (ETT69_01425) | - | 243148..244932 (+) | 1785 | WP_002986115.1 | ABC transporter ATP-binding protein | - |
| ETT69_RS01430 (ETT69_01430) | - | 245050..245817 (+) | 768 | WP_002986113.1 | epoxyqueuosine reductase QueH | - |
| ETT69_RS01435 (ETT69_01435) | - | 245927..246373 (+) | 447 | WP_002986111.1 | dUTP diphosphatase | - |
| ETT69_RS01440 (ETT69_01440) | radA | 246454..247815 (+) | 1362 | WP_002986109.1 | DNA repair protein RadA | Machinery gene |
Sequence
Protein
Download Length: 453 a.a. Molecular weight: 49386.68 Da Isoelectric Point: 6.0962
>NTDB_id=341151 ETT69_RS01440 WP_002986109.1 246454..247815(+) (radA) [Streptococcus pyogenes strain emm55]
MAKKKATFICQECGYQSPKYLGRCPNCSAWSSFVEEVEVKEVKNARVSLAGEKSRPVKLKDVDNISYHRTQTDMSEFNRV
LGGGVVPGSLILIGGDPGIGKSTLLLQVSTQLANKGTVLYVSGEESAEQIKLRSERLGDIDNEFYLYAETNMQAIRTEIE
NIKPDFLIIDSIQTIMSPDITGVQGSVSQVREVTAELMQLAKTNNIATFIVGHVTKEGTLAGPRMLEHMVDTVLYFEGER
HHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNPSQVFLEERLDGATGSAVVVTMEGSRPILAEVQSLVTPTVFGNAR
RTTTGLDFNRVSLIMAVLEKRCGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKEKPTSPQEAFLGEIGLTGEIR
RVTRIEQRINEAAKLGFTKVYAPKNALQGIDIPQGIEVVGVTTVGQVLKAVFS
MAKKKATFICQECGYQSPKYLGRCPNCSAWSSFVEEVEVKEVKNARVSLAGEKSRPVKLKDVDNISYHRTQTDMSEFNRV
LGGGVVPGSLILIGGDPGIGKSTLLLQVSTQLANKGTVLYVSGEESAEQIKLRSERLGDIDNEFYLYAETNMQAIRTEIE
NIKPDFLIIDSIQTIMSPDITGVQGSVSQVREVTAELMQLAKTNNIATFIVGHVTKEGTLAGPRMLEHMVDTVLYFEGER
HHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNPSQVFLEERLDGATGSAVVVTMEGSRPILAEVQSLVTPTVFGNAR
RTTTGLDFNRVSLIMAVLEKRCGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKEKPTSPQEAFLGEIGLTGEIR
RVTRIEQRINEAAKLGFTKVYAPKNALQGIDIPQGIEVVGVTTVGQVLKAVFS
Nucleotide
Download Length: 1362 bp
>NTDB_id=341151 ETT69_RS01440 WP_002986109.1 246454..247815(+) (radA) [Streptococcus pyogenes strain emm55]
ATGGCAAAGAAAAAAGCAACCTTTATCTGTCAGGAGTGTGGCTACCAGTCGCCAAAGTATTTAGGGCGCTGTCCAAATTG
CTCGGCCTGGTCTTCTTTTGTGGAAGAAGTAGAGGTCAAAGAAGTCAAAAATGCCCGTGTTAGTCTAGCTGGAGAAAAGT
CCAGACCGGTTAAACTAAAAGATGTGGATAATATTAGTTATCACAGAACACAGACTGACATGTCTGAATTTAATAGAGTT
CTTGGAGGGGGTGTGGTTCCTGGAAGCTTGATTTTAATTGGTGGTGATCCAGGTATTGGAAAATCCACCTTACTCTTGCA
GGTATCCACGCAGCTCGCTAATAAGGGAACGGTTCTCTATGTGTCTGGGGAAGAATCAGCAGAGCAGATTAAACTGCGGA
GTGAGCGTCTGGGTGATATTGACAATGAATTTTACCTCTATGCCGAAACCAATATGCAAGCTATTCGCACAGAAATTGAA
AATATTAAACCAGATTTTTTAATTATTGACTCCATTCAGACTATCATGAGCCCTGATATTACAGGTGTTCAAGGATCAGT
CAGTCAGGTGAGAGAAGTCACTGCAGAATTGATGCAGCTTGCAAAGACGAACAACATTGCAACCTTTATTGTGGGTCATG
TCACCAAGGAAGGAACCTTGGCTGGGCCTCGTATGTTAGAACACATGGTGGATACCGTTCTCTACTTTGAAGGGGAAAGG
CATCACACCTTTCGCATTCTGCGGGCTGTGAAAAACCGCTTTGGCTCCACTAATGAGATTGGCATCTTTGAAATGCAGTC
TGGCGGCTTGGTAGAGGTCTTAAATCCTAGTCAAGTCTTTTTAGAGGAACGCTTAGATGGGGCAACAGGATCGGCTGTCG
TTGTAACGATGGAAGGAAGTCGTCCTATTTTAGCAGAGGTGCAATCTTTAGTGACACCAACCGTTTTTGGCAATGCCAGA
CGAACCACTACGGGACTTGATTTCAATCGCGTAAGCCTAATAATGGCAGTTTTAGAAAAGCGCTGTGGTTTACTCTTACA
AAATCAAGATGCCTACCTCAAGTCGGCTGGTGGTGTCAAACTAGACGAACCTGCCATTGATTTGGCAGTCGCTGTGGCTA
TCGCATCCAGTTATAAGGAAAAACCAACCAGCCCTCAAGAAGCTTTCTTAGGCGAGATCGGGTTAACAGGTGAGATTCGG
CGAGTGACCCGTATTGAGCAACGGATTAATGAAGCAGCAAAGCTTGGCTTTACCAAGGTCTATGCTCCTAAAAATGCCTT
GCAAGGCATTGATATCCCTCAAGGTATTGAGGTTGTTGGAGTGACTACGGTTGGTCAGGTTTTAAAGGCAGTTTTTAGCT
AG
ATGGCAAAGAAAAAAGCAACCTTTATCTGTCAGGAGTGTGGCTACCAGTCGCCAAAGTATTTAGGGCGCTGTCCAAATTG
CTCGGCCTGGTCTTCTTTTGTGGAAGAAGTAGAGGTCAAAGAAGTCAAAAATGCCCGTGTTAGTCTAGCTGGAGAAAAGT
CCAGACCGGTTAAACTAAAAGATGTGGATAATATTAGTTATCACAGAACACAGACTGACATGTCTGAATTTAATAGAGTT
CTTGGAGGGGGTGTGGTTCCTGGAAGCTTGATTTTAATTGGTGGTGATCCAGGTATTGGAAAATCCACCTTACTCTTGCA
GGTATCCACGCAGCTCGCTAATAAGGGAACGGTTCTCTATGTGTCTGGGGAAGAATCAGCAGAGCAGATTAAACTGCGGA
GTGAGCGTCTGGGTGATATTGACAATGAATTTTACCTCTATGCCGAAACCAATATGCAAGCTATTCGCACAGAAATTGAA
AATATTAAACCAGATTTTTTAATTATTGACTCCATTCAGACTATCATGAGCCCTGATATTACAGGTGTTCAAGGATCAGT
CAGTCAGGTGAGAGAAGTCACTGCAGAATTGATGCAGCTTGCAAAGACGAACAACATTGCAACCTTTATTGTGGGTCATG
TCACCAAGGAAGGAACCTTGGCTGGGCCTCGTATGTTAGAACACATGGTGGATACCGTTCTCTACTTTGAAGGGGAAAGG
CATCACACCTTTCGCATTCTGCGGGCTGTGAAAAACCGCTTTGGCTCCACTAATGAGATTGGCATCTTTGAAATGCAGTC
TGGCGGCTTGGTAGAGGTCTTAAATCCTAGTCAAGTCTTTTTAGAGGAACGCTTAGATGGGGCAACAGGATCGGCTGTCG
TTGTAACGATGGAAGGAAGTCGTCCTATTTTAGCAGAGGTGCAATCTTTAGTGACACCAACCGTTTTTGGCAATGCCAGA
CGAACCACTACGGGACTTGATTTCAATCGCGTAAGCCTAATAATGGCAGTTTTAGAAAAGCGCTGTGGTTTACTCTTACA
AAATCAAGATGCCTACCTCAAGTCGGCTGGTGGTGTCAAACTAGACGAACCTGCCATTGATTTGGCAGTCGCTGTGGCTA
TCGCATCCAGTTATAAGGAAAAACCAACCAGCCCTCAAGAAGCTTTCTTAGGCGAGATCGGGTTAACAGGTGAGATTCGG
CGAGTGACCCGTATTGAGCAACGGATTAATGAAGCAGCAAAGCTTGGCTTTACCAAGGTCTATGCTCCTAAAAATGCCTT
GCAAGGCATTGATATCCCTCAAGGTATTGAGGTTGTTGGAGTGACTACGGTTGGTCAGGTTTTAAAGGCAGTTTTTAGCT
AG
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| radA | Streptococcus mitis NCTC 12261 |
85.872 |
100 |
0.859 |
| radA | Streptococcus pneumoniae D39 |
85.651 |
100 |
0.857 |
| radA | Streptococcus pneumoniae R6 |
85.651 |
100 |
0.857 |
| radA | Streptococcus pneumoniae Rx1 |
85.651 |
100 |
0.857 |
| radA | Streptococcus mitis SK321 |
85.651 |
100 |
0.857 |
| radA | Streptococcus pneumoniae TIGR4 |
85.651 |
100 |
0.857 |
| radA | Bacillus subtilis subsp. subtilis str. 168 |
61.369 |
100 |
0.614 |