Detailed information NTG0341014

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: ETT72_RS06700
• Genome accession: NZ_CP035427
• Coordinates: 1274644..1275681 (-)
• Length: 345 a.a.
• NCBI ID: WP_032464469.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain emm74
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1269644..1280681

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ETT72_RS06675 (ETT72_06670)	-	1269648..1270175 (-)	528	WP_002983837.1	Dps family protein	-
ETT72_RS06680 (ETT72_06675)	-	1270403..1271029 (+)	627	WP_002983834.1	A24 family peptidase	-
ETT72_RS06685 (ETT72_06680)	rlmN	1271111..1272190 (-)	1080	WP_002992788.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
ETT72_RS06690 (ETT72_06685)	-	1272194..1272814 (-)	621	WP_032464468.1	YutD family protein	-
ETT72_RS06695 (ETT72_06690)	-	1273262..1274239 (-)	978	WP_002994809.1	LacI family DNA-binding transcriptional regulator	-
ETT72_RS06700 (ETT72_06695)	sepM	1274644..1275681 (-)	1038	WP_032464469.1	SepM family pheromone-processing serine protease	Regulator
ETT72_RS06705 (ETT72_06700)	coaD	1275668..1276159 (-)	492	WP_002983821.1	pantetheine-phosphate adenylyltransferase	-
ETT72_RS06710 (ETT72_06705)	rsmD	1276149..1276688 (-)	540	WP_002983819.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
ETT72_RS06715 (ETT72_06710)	asnA	1276811..1277803 (-)	993	WP_032464470.1	aspartate--ammonia ligase	-
ETT72_RS06720 (ETT72_06715)	arcC	1278116..1279066 (-)	951	WP_010922501.1	carbamate kinase	-
ETT72_RS06725 (ETT72_06720)	-	1279086..1280417 (-)	1332	WP_032464471.1	dipeptidase	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37527.17 Da
• Isoelectric Point: 9.5788

>NTDB_id=341014 ETT72_RS06700 WP_032464469.1 1274644..1275681(-) (sepM) [Streptococcus pyogenes strain emm74]
MKRLKKIKWWLVGLLALISLLLALFFPLPYYIEMPGGAYDIRTVLQVNGKEDKRKGAYQFVAVGISRASLAQLLYAWLTP
FTEISTAEDTTGGYSDADFLRINQFYMETSQNAAIYQALSLAGKPVTLDYKGVYVLDVNNESTFKGTLHLADTVTGVNGN
QFTSSAELIDYVSHLKLGDEVTVQFTSDNKPKKGVGRIIKLKNGKNGIGIALTDHTSVNSEDTVIFSTKGVGGPSAGLMF
TLDIYDQITKEDLRKGRTIAGTGTIGKDGEVGDIGGAGLKVVAAAEAGADIFFVPNNPVDKEIKKVNPNAISNYEEAKRA
AKRLKTKMKIVPVTTVQEALVYLRK

Nucleotide

• Length: 1038 bp

>NTDB_id=341014 ETT72_RS06700 WP_032464469.1 1274644..1275681(-) (sepM) [Streptococcus pyogenes strain emm74]
ATGAAAAGACTTAAAAAAATCAAATGGTGGTTAGTGGGTCTGCTAGCTTTAATCTCTTTGTTGCTAGCGTTATTTTTTCC
GCTACCTTATTATATTGAAATGCCTGGAGGCGCTTACGATATTCGGACTGTCTTACAAGTCAATGGCAAAGAAGACAAAC
GAAAAGGAGCTTACCAGTTTGTTGCAGTGGGCATTAGTCGTGCCAGCCTCGCGCAGCTATTATATGCTTGGCTGACACCG
TTTACTGAAATTAGTACAGCAGAAGATACAACAGGCGGATACAGCGATGCTGATTTCCTTCGAATTAATCAATTTTACAT
GGAAACATCACAAAATGCAGCTATTTATCAAGCTTTATCCTTAGCTGGAAAACCAGTTACATTAGATTATAAAGGCGTAT
ATGTTTTAGACGTAAACAACGAATCTACTTTTAAAGGAACGCTACACTTAGCAGATACTGTAACAGGTGTAAATGGTAAC
CAGTTTACTAGTTCAGCAGAACTTATTGACTATGTTTCTCACCTAAAACTAGGGGATGAAGTTACGGTTCAGTTTACGAG
TGATAATAAGCCTAAAAAAGGAGTTGGCCGTATTATCAAACTGAAAAATGGGAAAAATGGGATTGGCATTGCCTTGACTG
ATCATACAAGTGTCAATTCAGAAGACACAGTGATCTTTAGTACTAAAGGAGTAGGAGGACCTAGTGCTGGTCTAATGTTT
ACTCTTGATATATATGATCAAATAACTAAAGAAGATTTACGCAAGGGCCGTACAATTGCAGGTACAGGAACTATTGGCAA
GGATGGCGAAGTAGGAGATATTGGTGGTGCAGGTCTTAAAGTAGTTGCAGCAGCTGAAGCTGGTGCAGATATATTTTTTG
TTCCGAATAATCCTGTTGATAAGGAAATTAAAAAAGTTAATCCAAATGCTATAAGTAATTACGAAGAAGCCAAACGGGCA
GCCAAACGACTAAAGACCAAAATGAAGATTGTTCCTGTTACGACTGTTCAAGAGGCACTGGTTTATCTTCGCAAATAA

Domains

Predicted by InterproScan.

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (233-309)

• PDZ domain (PDZ_2) (129-192)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	68.986	100	0.69