Detailed information NTG0340958

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: ETT73_RS06155
• Genome accession: NZ_CP035426
• Coordinates: 1193650..1194687 (-)
• Length: 345 a.a.
• NCBI ID: WP_111693301.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain emm57
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1188650..1199687

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ETT73_RS06130 (ETT73_06125)	-	1188654..1189181 (-)	528	WP_014635585.1	Dps family protein	-
ETT73_RS06135 (ETT73_06130)	-	1189409..1190035 (+)	627	WP_002989076.1	A24 family peptidase	-
ETT73_RS06140 (ETT73_06135)	rlmN	1190117..1191196 (-)	1080	WP_136112628.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
ETT73_RS06145 (ETT73_06140)	-	1191200..1191820 (-)	621	WP_002992791.1	YutD family protein	-
ETT73_RS06150 (ETT73_06145)	-	1192268..1193245 (-)	978	WP_002994809.1	LacI family DNA-binding transcriptional regulator	-
ETT73_RS06155 (ETT73_06150)	sepM	1193650..1194687 (-)	1038	WP_111693301.1	SepM family pheromone-processing serine protease	Regulator
ETT73_RS06160 (ETT73_06155)	coaD	1194674..1195165 (-)	492	WP_002983821.1	pantetheine-phosphate adenylyltransferase	-
ETT73_RS06165 (ETT73_06160)	rsmD	1195155..1195694 (-)	540	WP_002983819.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
ETT73_RS06170 (ETT73_06165)	asnA	1195817..1196809 (-)	993	WP_023611792.1	aspartate--ammonia ligase	-
ETT73_RS06175 (ETT73_06170)	arcC	1197123..1198073 (-)	951	WP_009880962.1	carbamate kinase	-
ETT73_RS06180 (ETT73_06175)	-	1198093..1199424 (-)	1332	WP_136276610.1	dipeptidase	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37527.22 Da
• Isoelectric Point: 9.6692

>NTDB_id=340958 ETT73_RS06155 WP_111693301.1 1193650..1194687(-) (sepM) [Streptococcus pyogenes strain emm57]
MKRLKKIKWWLVGLLALISLLLALFFPLPYYIEMPGGAYDIRSVLQVNGKEDKRKGAYQFVAVGISRASLAQLLYAWLTP
FTEISTAEDTTGGYSDADFLRINQFYMETSQNAAIYQALSLAGKPVTLDYKGVYVLDVNNESTFKGTLHLADTVTGVNGK
QFTSSAELIDYVSHLKLGDEVTVQFTSDNKPKKGVGRIIKLKNGKNGIGIALTDHTSVNSEDTVIFSTKGVGGPSAGLMF
TLDIYDQITKEDLRKGRTIAGTGTIGKDGEVGDIGGAGLKVVAAAEAGADIFFVPNNPVDKEIKKVNPNAISNYEEAKRA
AKRLKTKMKIVPVTTVQEALVYLRK

Nucleotide

• Length: 1038 bp

>NTDB_id=340958 ETT73_RS06155 WP_111693301.1 1193650..1194687(-) (sepM) [Streptococcus pyogenes strain emm57]
ATGAAAAGACTTAAAAAAATCAAATGGTGGTTAGTGGGTCTGCTAGCTTTAATCTCTTTGTTGCTAGCGTTATTTTTTCC
GCTACCTTATTATATTGAAATGCCTGGAGGCGCTTACGATATTCGGTCTGTCTTACAAGTCAATGGCAAAGAAGACAAAC
GAAAAGGAGCTTACCAGTTTGTTGCAGTGGGCATTAGTCGTGCCAGCCTCGCTCAGCTATTATATGCTTGGCTGACACCG
TTTACTGAAATTAGTACAGCAGAAGATACAACAGGCGGATACAGCGATGCTGATTTCCTTCGAATTAATCAATTTTACAT
GGAAACATCACAAAATGCAGCTATTTATCAAGCTTTATCCTTAGCTGGAAAACCAGTTACATTAGATTATAAAGGCGTAT
ATGTTTTAGACGTAAACAACGAATCTACTTTTAAAGGAACGTTACACTTAGCAGATACTGTAACAGGTGTAAATGGTAAA
CAGTTTACTAGTTCAGCAGAACTTATTGACTATGTTTCTCACCTAAAACTAGGAGATGAAGTTACGGTTCAGTTTACGAG
TGATAATAAGCCTAAAAAAGGAGTTGGCCGTATTATCAAACTGAAAAATGGGAAAAATGGGATTGGCATTGCCTTGACTG
ATCATACAAGTGTCAATTCAGAAGACACAGTGATCTTTAGTACTAAAGGAGTAGGAGGACCTAGTGCTGGTCTAATGTTT
ACTCTTGATATATATGATCAAATAACTAAAGAAGATTTACGCAAGGGCCGTACAATTGCAGGTACAGGAACTATTGGCAA
GGATGGCGAAGTAGGAGATATTGGTGGTGCAGGTCTTAAAGTAGTTGCAGCAGCTGAAGCTGGTGCAGATATATTTTTTG
TTCCGAATAATCCTGTTGATAAGGAAATTAAAAAAGTTAATCCAAATGCTATAAGTAATTACGAAGAAGCCAAACGGGCA
GCCAAACGACTAAAGACCAAAATGAAGATTGTTCCTGTTACGACTGTTCAAGAGGCACTGGTTTATCTTCGCAAATAG

Domains

Predicted by InterproScan.

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (233-309)

• PDZ domain (PDZ_2) (129-192)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	69.565	100	0.696