Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   ES969_RS16405 Genome accession   NZ_CP035402
Coordinates   3019252..3019896 (-) Length   214 a.a.
NCBI ID   WP_003220716.1    Uniprot ID   -
Organism   Bacillus subtilis strain SRCM103576     
Function   promoting transcription of comS (predicted from homology)   
Competence regulation

Genomic Context

Location: 3014252..3024896
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ES969_RS16370 (ES969_16370) mrpB 3015444..3015875 (+) 432 WP_003228819.1 Na(+)/H(+) antiporter subunit B -
  ES969_RS16375 (ES969_16375) mrpC 3015875..3016216 (+) 342 WP_014480700.1 Na(+)/H(+) antiporter subunit C -
  ES969_RS16380 (ES969_16380) mrpD 3016209..3017690 (+) 1482 WP_033881486.1 Na+/H+ antiporter subunit D -
  ES969_RS16385 (ES969_16385) mrpE 3017696..3018172 (+) 477 WP_003228815.1 Na+/H+ antiporter subunit E -
  ES969_RS16390 (ES969_16390) mrpF 3018172..3018456 (+) 285 WP_003228814.1 Na(+)/H(+) antiporter subunit F1 -
  ES969_RS16395 (ES969_16395) mnhG 3018440..3018814 (+) 375 WP_014477830.1 monovalent cation/H(+) antiporter subunit G -
  ES969_RS16400 (ES969_16400) yuxO 3018853..3019233 (-) 381 WP_069837723.1 hotdog fold thioesterase -
  ES969_RS16405 (ES969_16405) comA 3019252..3019896 (-) 645 WP_003220716.1 two-component system response regulator ComA Regulator
  ES969_RS16410 (ES969_16410) comP 3019977..3022289 (-) 2313 WP_103330147.1 sensor histidine kinase Regulator
  ES969_RS16415 (ES969_16415) comX 3022305..3022526 (-) 222 WP_014480704.1 competence pheromone ComX -
  ES969_RS16420 (ES969_16420) - 3022528..3023391 (-) 864 WP_014480705.1 polyprenyl synthetase family protein -
  ES969_RS16425 (ES969_16425) degQ 3023576..3023716 (-) 141 WP_003220708.1 degradation enzyme regulation protein DegQ Regulator
  ES969_RS16430 (ES969_16430) - 3023938..3024063 (+) 126 WP_003228793.1 hypothetical protein -
  ES969_RS16435 (ES969_16435) - 3024178..3024546 (+) 369 WP_046381300.1 hypothetical protein -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 24128.51 Da        Isoelectric Point: 4.6857

>NTDB_id=340279 ES969_RS16405 WP_003220716.1 3019252..3019896(-) (comA) [Bacillus subtilis strain SRCM103576]
MKKILVIDDHPAVMEGTKTILETDSNLSVDCLSPEPSEQFIKQHDFSSYDLILMDLNLGGEVNGMELSKQILQENPHCKI
IVYTGYEVEDYFEEAIRAGLHGAISKTESKEKITQYIYHVLNGEILVDFAYFKQLMTQQKTKPAPSSQKEQDVLTPRECL
ILQEVEKGFTNQEIADALHLSKRSIEYSLTSIFNKLNVGSRTEAVLIAKSDGVL

Nucleotide


Download         Length: 645 bp        

>NTDB_id=340279 ES969_RS16405 WP_003220716.1 3019252..3019896(-) (comA) [Bacillus subtilis strain SRCM103576]
ATGAAAAAGATACTAGTGATTGATGACCATCCGGCTGTCATGGAAGGCACCAAGACAATTTTGGAAACGGATTCGAATTT
GTCTGTTGACTGTCTCAGTCCTGAACCGAGCGAACAGTTTATCAAGCAGCATGATTTCTCGTCATATGATCTCATTTTAA
TGGATCTGAATCTAGGCGGCGAGGTCAATGGGATGGAGCTTTCTAAACAGATTTTACAAGAGAATCCTCATTGTAAAATT
ATCGTGTATACCGGTTATGAGGTCGAGGATTATTTCGAGGAAGCGATTCGTGCGGGTCTGCACGGTGCCATCAGCAAAAC
GGAATCTAAAGAAAAGATCACCCAATACATATACCACGTACTCAATGGAGAAATTTTAGTCGATTTTGCTTACTTTAAAC
AGCTGATGACTCAGCAAAAAACAAAGCCGGCTCCTTCCTCTCAAAAAGAACAAGATGTGCTCACACCTAGAGAATGCCTG
ATTCTTCAAGAAGTTGAAAAAGGATTTACAAACCAAGAAATCGCAGATGCCCTTCATTTAAGCAAGCGGTCCATTGAATA
CAGCTTGACATCGATTTTCAATAAGCTGAATGTCGGTTCACGGACGGAAGCGGTTTTGATTGCGAAATCAGACGGTGTAC
TTTAA

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, luxR family (GerE)

(152-208)

Response regulator receiver domain (Response_reg)

(4-117)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Bacillus subtilis subsp. subtilis str. 168

100

100

1

Multiple sequence alignment