Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   ES965_RS06225 Genome accession   NZ_CP035391
Coordinates   1196859..1197515 (+) Length   218 a.a.
NCBI ID   WP_003245194.1    Uniprot ID   A0AAE2VF25
Organism   Bacillus subtilis strain SRCM103689     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1191859..1202515
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ES965_RS06195 (ES965_06195) oppF 1192111..1193028 (+) 918 WP_003245567.1 oligopeptide ABC transporter ATP-binding protein OppF -
  ES965_RS06200 (ES965_06200) yjbB 1193136..1194353 (+) 1218 WP_077670803.1 MFS transporter -
  ES965_RS06205 (ES965_06205) yjbC 1194517..1195095 (+) 579 WP_003224597.1 GNAT family N-acetyltransferase -
  ES965_RS06210 (ES965_06210) spx 1195276..1195671 (+) 396 WP_014476435.1 transcriptional regulator Spx -
  ES965_RS06215 (ES965_06215) yjbE 1195926..1196582 (-) 657 WP_003232944.1 TerC family protein -
  ES965_RS06220 (ES965_06220) - 1196752..1196892 (+) 141 WP_119122854.1 hypothetical protein -
  ES965_RS06225 (ES965_06225) mecA 1196859..1197515 (+) 657 WP_003245194.1 adaptor protein MecA Regulator
  ES965_RS06230 (ES965_06230) - 1197510..1197632 (-) 123 WP_003245684.1 hypothetical protein -
  ES965_RS06235 (ES965_06235) coiA 1197676..1198827 (+) 1152 WP_129092392.1 competence protein CoiA Machinery gene
  ES965_RS06240 (ES965_06240) pepF 1199057..1200886 (+) 1830 WP_003245178.1 oligoendopeptidase F -
  ES965_RS06245 (ES965_06245) - 1200924..1201091 (-) 168 WP_003244944.1 hypothetical protein -
  ES965_RS06255 (ES965_06255) spxH 1201405..1202304 (-) 900 WP_024573348.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25763.69 Da        Isoelectric Point: 4.1174

>NTDB_id=339606 ES965_RS06225 WP_003245194.1 1196859..1197515(+) (mecA) [Bacillus subtilis strain SRCM103689]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHEEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPASEDLDALLDDFQKEEQAVNQEEKEQKLQFVLRFGDFEDVISLSKLNVNGSKTTLYSFENR
YYLYVDFCNMTDEEVENQLSILLEYATESSISIHRLEEYGKLIISEHALETIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=339606 ES965_RS06225 WP_003245194.1 1196859..1197515(+) (mecA) [Bacillus subtilis strain SRCM103689]
ATGGAAATTGAAAGAATTAACGAGCATACAGTAAAATTTTATATGTCTTACGGAGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATTTGGTATAACCGTGAGCGCAGTGAAGAACTATTCTGGGAAGTCATGGATGAAGTTCATGAAGAAGAGGAAT
TCGCTGTGGAAGGCCCACTTTGGATTCAAGTTCAGGCACTGGACAAAGGATTAGAAATCATCGTCACAAAAGCCCAGCTT
TCCAAAGACGGACAAAAGCTCGAACTGCCGATTCCTGAGGATAAAAAGCAAGAACCAGCATCTGAGGATCTTGACGCCTT
GCTGGATGATTTCCAGAAAGAAGAGCAAGCCGTCAATCAGGAAGAGAAGGAGCAAAAGCTTCAATTTGTCTTGCGATTTG
GCGATTTTGAGGATGTTATTTCTCTATCTAAATTGAACGTTAACGGAAGCAAAACGACTTTATATTCGTTTGAGAACCGA
TATTATTTATATGTAGATTTTTGCAATATGACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGCTGGAGTACGCAAC
TGAATCCTCAATCAGCATACACCGTCTTGAAGAGTACGGCAAGCTGATTATTTCAGAGCATGCTCTAGAAACGATAAAAA
AACACTTTGCATCATAG

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

100

100

1

Multiple sequence alignment