Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   ES963_RS06350 Genome accession   NZ_CP035390
Coordinates   1218572..1219228 (+) Length   218 a.a.
NCBI ID   WP_003232942.1    Uniprot ID   A0AAQ3ENL6
Organism   Bacillus subtilis strain SRCM103641     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1213572..1224228
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ES963_RS06320 (ES963_06320) oppF 1214037..1214954 (+) 918 WP_003239287.1 oligopeptide ABC transporter ATP-binding protein OppF -
  ES963_RS06325 (ES963_06325) yjbB 1215061..1216278 (+) 1218 WP_087614503.1 MFS transporter -
  ES963_RS06330 (ES963_06330) yjbC 1216442..1217020 (+) 579 WP_003224597.1 GNAT family N-acetyltransferase -
  ES963_RS06335 (ES963_06335) spx 1217201..1217596 (+) 396 WP_014476435.1 transcriptional regulator Spx -
  ES963_RS06340 (ES963_06340) yjbE 1217639..1218295 (-) 657 WP_003232944.1 TerC family protein -
  ES963_RS06345 (ES963_06345) - 1218465..1218605 (+) 141 WP_119122854.1 hypothetical protein -
  ES963_RS06350 (ES963_06350) mecA 1218572..1219228 (+) 657 WP_003232942.1 adaptor protein MecA Regulator
  ES963_RS06355 (ES963_06355) - 1219223..1219345 (-) 123 WP_021479547.1 hypothetical protein -
  ES963_RS06360 (ES963_06360) coiA 1219389..1220540 (+) 1152 WP_087614504.1 competence protein CoiA Machinery gene
  ES963_RS06365 (ES963_06365) pepF 1220770..1222599 (+) 1830 WP_173401378.1 oligoendopeptidase F -
  ES963_RS06370 (ES963_06370) - 1222637..1222804 (-) 168 WP_003244944.1 hypothetical protein -
  ES963_RS06380 (ES963_06380) spxH 1223119..1224018 (-) 900 WP_003245184.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25762.62 Da        Isoelectric Point: 4.0841

>NTDB_id=339526 ES963_RS06350 WP_003232942.1 1218572..1219228(+) (mecA) [Bacillus subtilis strain SRCM103641]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHEEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPASEDLDALLDDFQKEEQAVNQEEKEQKLQFVLRFGDFEDVISLSNLNVNGSKTTLYSFENR
YYLYVDFCNMTDEEVENQLSILLEYANESSISIHRLEEYGKLIISEHALETIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=339526 ES963_RS06350 WP_003232942.1 1218572..1219228(+) (mecA) [Bacillus subtilis strain SRCM103641]
ATGGAAATTGAAAGAATTAACGAGCATACAGTAAAATTTTATATGTCTTACGGAGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATTTGGTATAACCGTGAGCGCAGTGAAGAACTTTTCTGGGAAGTCATGGATGAAGTTCATGAAGAAGAGGAAT
TCGCTGTGGAAGGCCCACTTTGGATTCAAGTTCAGGCACTGGACAAAGGATTAGAAATCATCGTCACAAAAGCCCAGCTT
TCCAAAGACGGACAAAAGCTCGAACTGCCGATTCCTGAGGATAAAAAGCAAGAACCAGCATCTGAGGATCTTGACGCCTT
GCTGGATGATTTCCAGAAAGAAGAGCAAGCCGTCAATCAGGAAGAGAAGGAGCAAAAGCTTCAATTTGTCTTGCGATTTG
GCGATTTTGAGGATGTTATTTCTCTATCTAATTTGAACGTTAACGGAAGCAAAACGACTTTATATTCGTTTGAGAACCGA
TATTATTTATATGTAGATTTTTGCAATATGACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGCTGGAGTACGCAAA
TGAATCCTCAATCAGCATACACCGTCTTGAAGAGTACGGCAAGCTGATTATTTCAGAGCATGCTCTAGAAACGATAAAAA
AACACTTTGCATCATAG

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

99.083

100

0.991

Multiple sequence alignment