Detailed information NTG0033946

Bioinformatically predicted

Overview

• Name: luxQ
• Type: Regulator
• Locus tag: VC395_RS17045
• Genome accession: NC_012583
• Coordinates: 522513..525086 (+)
• Length: 857 a.a.
• NCBI ID: WP_001026313.1
• Uniprot ID: A0A0H3AFP5
• Organism: Vibrio cholerae O395
• Function: autoinducer sensor (predicted from homology) Competence regulation

Genomic Context

Location: 517513..530086

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
VC395_RS17005 (VC395_A0570)	-	517561..517812 (-)	252	WP_001882582.1	YgjV family protein	-
VC395_RS17015 (VC395_A0572)	-	518225..518545 (-)	321	WP_001089529.1	DUF496 family protein	-
VC395_RS17020 (VC395_A0573)	-	518733..518930 (+)	198	WP_001246071.1	hypothetical protein	-
VC395_RS17025 (VC395_A0574)	-	518972..519622 (+)	651	WP_001025632.1	YceH family protein	-
VC395_RS17030 (VC395_A0575)	-	519622..519927 (+)	306	WP_000448828.1	GIY-YIG nuclease family protein	-
VC395_RS17035 (VC395_A0576)	traF	520029..521189 (+)	1161	WP_001025868.1	conjugal transfer protein TraF	-
VC395_RS17040 (VC395_A0577)	luxP	521401..522495 (+)	1095	WP_000823677.1	substrate-binding domain-containing protein	Regulator
VC395_RS17045 (VC395_A0578)	luxQ	522513..525086 (+)	2574	WP_001026313.1	quorum-sensing autoinducer 2 sensor kinase/phosphatase LuxQ	Regulator
VC395_RS17050 (VC395_A0579)	-	525078..525743 (-)	666	WP_000268198.1	flagellar brake protein	-
VC395_RS17055 (VC395_A0580)	-	525987..526505 (-)	519	WP_000914961.1	hypothetical protein	-
VC395_RS17065 (VC395_A0582)	-	526743..527141 (-)	399	WP_000831416.1	YgiW/YdeI family stress tolerance OB fold protein	-
VC395_RS17070 (VC395_A0583)	-	527343..527648 (+)	306	WP_001181132.1	hypothetical protein	-

Sequence

Protein

• Length: 857 a.a.
• Molecular weight: 97059.92 Da
• Isoelectric Point: 6.0968

>NTDB_id=33946 VC395_RS17045 WP_001026313.1 522513..525086(+) (luxQ) [Vibrio cholerae O395]
MNIRPSQIKHKQRIASFITHAVVVVMGVLIVSVLFQSYQISSRLMSQERQRTSVQTSSLIQSLFDFRLAALRIHQDSTAK
NASLINALVSRDSSRLDEFFSSVDELELSNAPDLRFISSHDNILWDDGNASFYGIAQQELNKLIRRVAISGNWHLVQTPS
EGKSVHILMRRSSLIEAGTGQVVGYLYVGIVLNDNFALLENIRSGSNSENLVLAVDTTPLVSTLKGNEPYSLDYVVHSAK
DAMRDSFIVGQTFLEVESVPTYLCVYSIQTNQNVLTLRDNFYFWMAFALISMIGVSIASRWWLQKRIQREIETLMNYTHK
LMDLDTKSEFIGSKIYEFDYFGRTLEQSFRRLANKEKQFEDLFNFALSPTMLWNTSGRLIRMNPSAQIQFLREDAQNHFL
FEILERQLLPTITKAAQGDNPSDVTTEVDGRVYRWNLSPIMVEGQIISIITQGQDITTIAEAEKQSQAARREAEESARVR
AEFLAKMSHELRTPLNGVLGVSQLLKRTPLNDEQREHVAVLCSSGEHLLAVLNDILDFSRLEQGKFRIQKNEFRLKELVC
AIDRIYRPLCNEKGLELVVNSNITTAAIVRSDQIRINQILFNLLNNAIKFTHQGSIRVELQLIEGDPLAQLVIQVVDTGI
GIREQDLTVIFEPFMQAESTTTREYGGSGLGLTIVHSLVEMLSGQLHVSSEYGIGTRFEIQLPIELVEKPDAPQQLLPAP
DPQPLFDKTLRVLLVEDNHTNAFIAQAFCRKYGLDVSWVTDGLQAIEELKIHDYDLVLMDNQLPYLDGVETTRTIKKVLH
LPVVVYACTADGLEETRQAFFHAGAEYVLVKPLKEQTLHKALEHFKHHHGQKNAGLN

Nucleotide

• Length: 2574 bp

>NTDB_id=33946 VC395_RS17045 WP_001026313.1 522513..525086(+) (luxQ) [Vibrio cholerae O395]
TTGAACATTCGACCTAGCCAAATCAAGCATAAACAGCGCATCGCTTCATTTATCACCCATGCTGTCGTGGTGGTGATGGG
CGTTCTGATCGTCAGTGTATTATTCCAAAGTTACCAGATCAGTAGCCGCTTGATGTCTCAAGAAAGGCAACGCACCTCAG
TTCAAACCTCCAGCTTGATTCAAAGTTTGTTTGATTTTCGTCTTGCGGCACTGCGAATTCACCAGGACAGCACAGCCAAG
AACGCCAGTTTAATCAACGCACTTGTCAGCCGAGATTCGAGTCGGCTGGATGAATTCTTTTCGAGTGTCGATGAACTTGA
ACTTTCTAATGCGCCAGATCTGCGTTTTATCTCCAGTCACGACAACATCTTGTGGGATGATGGCAACGCCTCTTTTTACG
GCATTGCCCAGCAAGAGCTGAATAAGCTTATCCGCAGAGTGGCGATCAGTGGCAATTGGCACTTGGTTCAAACGCCCAGC
GAGGGAAAATCAGTCCATATTTTGATGCGTCGTTCATCACTGATTGAAGCGGGAACCGGGCAGGTTGTTGGGTATCTGTA
TGTAGGCATCGTACTCAATGATAACTTTGCGCTGTTGGAAAATATCCGCAGTGGCAGTAACTCAGAAAACCTAGTCCTTG
CCGTCGATACTACGCCGCTGGTTTCTACCTTGAAAGGCAATGAACCTTATTCGCTGGACTATGTGGTGCACAGCGCCAAA
GATGCTATGCGCGACAGCTTTATTGTTGGGCAAACCTTCTTAGAAGTGGAAAGTGTACCGACCTATCTGTGCGTCTACTC
GATTCAGACCAACCAAAATGTGCTCACCCTGCGGGATAATTTCTATTTTTGGATGGCGTTTGCGCTGATCAGTATGATCG
GTGTTTCCATCGCGTCACGCTGGTGGCTACAAAAACGCATTCAGCGTGAAATTGAAACCTTGATGAATTACACCCATAAA
TTGATGGATCTGGATACGAAAAGTGAGTTTATCGGTTCAAAAATTTATGAGTTCGACTATTTTGGGCGAACGTTGGAACA
ATCATTCCGTCGTCTCGCCAATAAAGAAAAGCAGTTTGAAGATCTGTTTAACTTTGCGCTCTCACCGACCATGCTTTGGA
ATACCTCTGGTCGGCTGATCCGCATGAACCCCTCAGCGCAAATCCAGTTTTTGCGCGAAGATGCGCAAAACCATTTCTTA
TTTGAGATTCTTGAACGCCAACTGTTGCCGACCATCACTAAGGCGGCACAGGGCGATAATCCGAGTGACGTCACAACCGA
AGTGGATGGTCGTGTGTACCGCTGGAACCTTTCGCCGATCATGGTGGAAGGGCAGATCATTTCCATCATTACTCAGGGGC
AAGATATCACCACCATCGCGGAAGCGGAGAAACAAAGCCAAGCCGCAAGGCGCGAAGCGGAAGAGTCGGCACGGGTCAGA
GCCGAGTTTTTGGCCAAAATGAGTCACGAATTGCGCACGCCGCTCAATGGTGTGCTCGGTGTTTCCCAACTGCTAAAACG
GACCCCACTCAATGATGAACAGCGCGAACACGTGGCTGTGTTATGCAGCAGTGGTGAACATTTGCTCGCGGTGCTGAATG
ACATCTTGGATTTTTCACGCTTAGAGCAGGGCAAATTCCGTATTCAAAAGAATGAGTTTCGCCTTAAAGAGTTGGTGTGC
GCGATTGACCGCATTTATCGACCTTTATGTAATGAAAAAGGCTTGGAACTGGTGGTGAATTCCAATATCACCACCGCAGC
GATTGTGCGCAGCGATCAGATCCGGATTAACCAAATCTTGTTCAATTTGCTCAATAACGCGATCAAGTTTACTCACCAAG
GTTCGATACGTGTCGAATTGCAATTAATTGAAGGCGATCCGTTAGCTCAACTGGTGATTCAAGTCGTCGATACGGGGATT
GGTATCCGCGAACAAGATTTAACGGTGATTTTTGAACCTTTCATGCAAGCTGAATCGACCACCACTCGAGAGTACGGCGG
AAGTGGTTTAGGCTTAACGATTGTGCACAGCTTAGTGGAAATGCTCAGTGGTCAACTGCACGTCAGCTCCGAGTATGGCA
TTGGTACACGTTTTGAAATTCAGTTACCGATTGAGCTGGTAGAAAAACCGGATGCGCCGCAGCAGTTGTTACCAGCTCCT
GATCCTCAACCGTTATTTGATAAAACTCTGCGTGTACTGTTGGTGGAGGATAACCACACCAATGCCTTTATTGCTCAAGC
ATTCTGTCGTAAATATGGCTTAGATGTGAGTTGGGTAACCGATGGACTACAGGCGATTGAAGAGCTCAAAATACATGACT
ACGACTTAGTGCTGATGGATAACCAGTTACCCTATTTGGATGGCGTTGAGACCACGCGCACCATCAAAAAGGTGCTGCAT
CTTCCGGTGGTGGTGTATGCCTGTACTGCGGATGGCTTAGAAGAAACACGGCAAGCATTTTTCCATGCGGGCGCGGAATA
TGTGTTAGTGAAGCCACTGAAAGAGCAGACTTTGCATAAAGCGCTGGAGCATTTCAAACATCATCATGGCCAAAAAAACG
CTGGCTTAAATTGA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (592-705)

• LuxQ, periplasmic (LuxQ-periplasm) (41-277)

• His Kinase A (phospho-acceptor) domain (HisKA) (480-544)

• Response regulator receiver domain (Response_reg) (732-842)

3D structure

• AlphaFold DB: A0A0H3AFP5

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
luxQ	Vibrio cholerae strain A1552	99.533	100	0.995