Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   ERW10_RS14840 Genome accession   NZ_CP035369
Coordinates   2834693..2835409 (-) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain LAC     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2829693..2840409
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ERW10_RS14820 (ERW10_14125) - 2830786..2831736 (+) 951 WP_000790330.1 LacI family DNA-binding transcriptional regulator -
  ERW10_RS14825 (ERW10_14130) - 2831885..2833369 (+) 1485 WP_000141414.1 sucrose-6-phosphate hydrolase -
  ERW10_RS14830 (ERW10_14135) - 2833366..2834326 (+) 961 Protein_2742 carbohydrate kinase -
  ERW10_RS14835 (ERW10_14140) - 2834514..2834621 (-) 108 WP_001790167.1 hypothetical protein -
  ERW10_RS14840 (ERW10_14145) agrA 2834693..2835409 (-) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  ERW10_RS14845 (ERW10_14150) agrC 2835428..2836720 (-) 1293 WP_001549202.1 quorum-sensing sensor histidine kinase AgrC -
  ERW10_RS14850 (ERW10_14155) agrD 2836745..2836885 (-) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  ERW10_RS14855 (ERW10_14160) agrB 2836882..2837451 (-) 570 WP_001105707.1 accessory gene regulator AgrB -
  ERW10_RS15365 hld 2837741..2837821 (+) 81 WP_000046022.1 delta-hemolysin -
  ERW10_RS14865 (ERW10_14170) - 2838418..2839203 (-) 786 WP_000867960.1 carbon-nitrogen family hydrolase -
  ERW10_RS14870 (ERW10_14175) - 2839564..2840190 (-) 627 WP_000522384.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=339403 ERW10_RS14840 WP_000688492.1 2834693..2835409(-) (agrA) [Staphylococcus aureus strain LAC]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=339403 ERW10_RS14840 WP_000688492.1 2834693..2835409(-) (agrA) [Staphylococcus aureus strain LAC]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCTGAATTAAGAACTCGAATTATAGACTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1

Multiple sequence alignment