Detailed information NTG0339400

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: ERW10_RS11515
• Genome accession: NZ_CP035369
• Coordinates: 2214926..2215813 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain LAC
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2209926..2220813

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ERW10_RS11485 (ERW10_10960)	-	2210658..2211419 (+)	762	WP_000323455.1	alpha/beta hydrolase family protein	-
ERW10_RS11490 (ERW10_10965)	-	2211664..2212119 (+)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
ERW10_RS15350	-	2212241..2212342 (+)	102	WP_000731972.1	SE2200 family small protein	-
ERW10_RS11500 (ERW10_10975)	-	2212402..2213826 (-)	1425	WP_000953744.1	alkaline phosphatase	-
ERW10_RS11505 (ERW10_10980)	-	2214024..2214224 (+)	201	WP_000604728.1	hypothetical protein	-
ERW10_RS11510 (ERW10_10985)	braR	2214250..2214915 (+)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
ERW10_RS11515 (ERW10_10990)	braS	2214926..2215813 (+)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
ERW10_RS11520 (ERW10_10995)	-	2215921..2216676 (+)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
ERW10_RS11525 (ERW10_11000)	-	2216673..2218673 (+)	2001	WP_000776751.1	ABC transporter permease	-
ERW10_RS11530 (ERW10_11005)	-	2219332..2219445 (+)	114	WP_001791776.1	hypothetical protein	-
ERW10_RS11540 (ERW10_11010)	-	2219827..2220087 (+)	261	WP_001789910.1	hypothetical protein	-
ERW10_RS11545 (ERW10_11015)	-	2220097..2220594 (+)	498	WP_001065268.1	glutathione peroxidase	-
ERW10_RS11550 (ERW10_11020)	-	2220702..2220794 (-)	93	WP_010956583.1	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=339400 ERW10_RS11515 WP_000143419.1 2214926..2215813(+) (braS) [Staphylococcus aureus strain LAC]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=339400 ERW10_RS11515 WP_000143419.1 2214926..2215813(+) (braS) [Staphylococcus aureus strain LAC]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997