Detailed information NTG0338979

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: EQ029_RS04780
• Genome accession: NZ_CP035291
• Coordinates: 1001664..1002710 (+)
• Length: 348 a.a.
• NCBI ID: WP_011275375.1
• Uniprot ID: A0A2A1K920
• Organism: Staphylococcus haemolyticus strain ATCC 29970
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 996664..1007710

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQ029_RS04755 (EQ029_04770)	map	997524..998276 (+)	753	WP_011275369.1	type I methionyl aminopeptidase	-
EQ029_RS04760 (EQ029_04775)	-	998401..999258 (-)	858	WP_011275370.1	SDR family oxidoreductase	-
EQ029_RS04765 (EQ029_04780)	-	999330..1000342 (-)	1013	Protein_944	HoxN/HupN/NixA family nickel/cobalt transporter	-
EQ029_RS04770 (EQ029_04785)	-	1000555..1000941 (+)	387	WP_011275373.1	hypothetical protein	-
EQ029_RS04775 (EQ029_04790)	liaF	1000966..1001667 (+)	702	WP_011275374.1	cell wall-active antibiotics response protein LiaF	-
EQ029_RS04780 (EQ029_04795)	vraS	1001664..1002710 (+)	1047	WP_011275375.1	sensor histidine kinase	Regulator
EQ029_RS04785 (EQ029_04800)	vraR	1002700..1003329 (+)	630	WP_011275376.1	two-component system response regulator VraR	Regulator
EQ029_RS04790 (EQ029_04805)	-	1003393..1004604 (-)	1212	WP_011275377.1	YihY/virulence factor BrkB family protein	-
EQ029_RS04795 (EQ029_04810)	-	1004801..1005085 (-)	285	WP_011275378.1	YtxH domain-containing protein	-
EQ029_RS04800 (EQ029_04815)	-	1005091..1005555 (-)	465	WP_011275379.1	low molecular weight protein-tyrosine-phosphatase	-
EQ029_RS04805 (EQ029_04820)	-	1005697..1005906 (+)	210	WP_011275380.1	DUF1128 domain-containing protein	-
EQ029_RS04810 (EQ029_04825)	-	1005920..1007167 (+)	1248	WP_011275381.1	aminopeptidase	-

Sequence

Protein

• Length: 348 a.a.
• Molecular weight: 40179.58 Da
• Isoelectric Point: 6.0550

>NTDB_id=338979 EQ029_RS04780 WP_011275375.1 1001664..1002710(+) (vraS) [Staphylococcus haemolyticus strain ATCC 29970]
MNHYLRAIGSMLILVYSMLTAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLVIILLCIIVGSILAYKINQQNQWIKS
QIEHAIEGETVGINDQNIELYNETIDLYQTLVPLNQELHRLRMKTQNLTNENYNMNDVKVKKIIENERQRLARELHDSVS
QQLFAASMMLSAIKETKLEAPLDQQIPVLEKMVQESQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVIHDI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNQQDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNREDDNNDD

Nucleotide

• Length: 1047 bp

>NTDB_id=338979 EQ029_RS04780 WP_011275375.1 1001664..1002710(+) (vraS) [Staphylococcus haemolyticus strain ATCC 29970]
ATGAACCACTACTTAAGAGCTATCGGTTCAATGCTTATACTAGTTTATAGCATGTTAACCGCGTTCTTATTTATAGATAA
AGTATTTGTTAATATTATCTATTTCCAAGGTATGTTTTATACTCAAATTTTTGGGATACCTGTTTTTCTATTTTTAAATT
TAGTCATCATTTTACTTTGTATTATAGTAGGTTCAATTCTCGCATATAAAATTAATCAACAAAATCAGTGGATTAAGTCG
CAAATTGAGCATGCCATTGAAGGAGAAACAGTAGGTATCAATGATCAAAACATTGAGCTCTATAACGAAACCATAGATCT
TTATCAAACATTAGTTCCTCTAAATCAAGAGTTGCACCGTTTACGAATGAAAACGCAAAACTTAACTAATGAAAATTACA
ATATGAATGATGTCAAAGTTAAGAAAATCATTGAGAATGAACGACAGAGATTAGCTCGCGAGTTACATGACTCTGTAAGT
CAACAACTTTTTGCAGCAAGTATGATGTTATCTGCTATAAAAGAAACAAAATTAGAGGCACCGCTTGATCAACAAATACC
AGTTTTAGAGAAAATGGTTCAGGAATCTCAACTTGAAATGCGCGCATTATTACTTCATTTGAGACCTTTAGGACTAAAAG
ATAAATCACTAGGTGAAGGTATCAAAGATTTAGTTATTGATTTGCAAAAGAAAGTGCCTATGAAAGTCATACACGATATT
CAAGATTTCAAGGTTCCTAAAGGTATAGAAGATCATTTATTTAGAATTACACAAGAGGCTATATCAAATACGTTAAGACA
TTCTAATGGAACTAAAGTCACAGTGGAATTATTTAACCAACAAGATTATCTATTACTTCGAATTCAAGATAATGGTAAGG
GATTCAATGTTGACGAGAAATTAGAACAAAGTTATGGATTAAAAAATATGAGAGAACGCGCATTAGAAATTGGTGCGACA
TTCCATATTGTTTCGTTACCGGATTCTGGAACGAGAATAGAAGTTAAAGCACCATTAAATAGGGAGGATGATAATAATGA
CGATTAA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (147-210)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

3D structure

• AlphaFold DB: A0A2A1K920

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	91.643	99.713	0.914