Detailed information
Bioinformatically predicted
Overview
| Name | clpX | Type | Regulator |
| Locus tag | EQH16_RS07610 | Genome accession | NZ_CP035264 |
| Coordinates | 1480881..1482113 (-) | Length | 410 a.a. |
| NCBI ID | WP_000106346.1 | Uniprot ID | A0A064C077 |
| Organism | Streptococcus pneumoniae strain TVO_1901921 | ||
| Function | require for competence development (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 1435358..1491177 | 1480881..1482113 | within | 0 |
Gene organization within MGE regions
Location: 1435358..1491177
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| EQH16_RS07285 (EQH16_07660) | - | 1435358..1436314 (-) | 957 | WP_238090264.1 | N-acetylmuramoyl-L-alanine amidase family protein | - |
| EQH16_RS07290 (EQH16_07665) | - | 1436323..1436655 (-) | 333 | WP_001186203.1 | phage holin | - |
| EQH16_RS07295 (EQH16_07670) | - | 1436659..1436958 (-) | 300 | WP_001811580.1 | hypothetical protein | - |
| EQH16_RS07300 (EQH16_07675) | - | 1436967..1437317 (-) | 351 | WP_000852245.1 | hypothetical protein | - |
| EQH16_RS07305 (EQH16_07680) | - | 1437320..1437523 (-) | 204 | WP_001091118.1 | hypothetical protein | - |
| EQH16_RS11260 | - | 1437504..1437620 (-) | 117 | WP_001063633.1 | hypothetical protein | - |
| EQH16_RS07310 | - | 1437617..1443946 (-) | 6330 | WP_409202194.1 | tail fiber domain-containing protein | - |
| EQH16_RS07315 (EQH16_07695) | - | 1445679..1446029 (-) | 351 | WP_000068020.1 | DUF6711 family protein | - |
| EQH16_RS07320 (EQH16_07700) | - | 1446038..1449691 (-) | 3654 | WP_050315488.1 | hypothetical protein | - |
| EQH16_RS07325 (EQH16_07705) | - | 1449678..1450028 (-) | 351 | WP_000478010.1 | hypothetical protein | - |
| EQH16_RS07330 (EQH16_07710) | - | 1450067..1450447 (-) | 381 | WP_001185635.1 | DUF6096 family protein | - |
| EQH16_RS07335 (EQH16_07715) | - | 1450452..1450865 (-) | 414 | WP_000880678.1 | phage tail tube protein | - |
| EQH16_RS07340 (EQH16_07720) | - | 1450868..1451236 (-) | 369 | WP_050279221.1 | hypothetical protein | - |
| EQH16_RS07345 (EQH16_07725) | - | 1451233..1451748 (-) | 516 | WP_050090558.1 | HK97-gp10 family putative phage morphogenesis protein | - |
| EQH16_RS07350 (EQH16_07730) | - | 1451723..1452061 (-) | 339 | WP_000478943.1 | hypothetical protein | - |
| EQH16_RS07355 (EQH16_07735) | - | 1452042..1452353 (-) | 312 | WP_000021219.1 | phage head-tail connector protein | - |
| EQH16_RS07360 (EQH16_07740) | - | 1452355..1452543 (-) | 189 | WP_000669349.1 | hypothetical protein | - |
| EQH16_RS07365 (EQH16_07745) | - | 1452533..1452715 (-) | 183 | WP_000054934.1 | Rho termination factor N-terminal domain-containing protein | - |
| EQH16_RS07370 (EQH16_07750) | - | 1452727..1453572 (-) | 846 | WP_000123890.1 | N4-gp56 family major capsid protein | - |
| EQH16_RS07375 (EQH16_07755) | - | 1453579..1454163 (-) | 585 | WP_001288024.1 | DUF4355 domain-containing protein | - |
| EQH16_RS07380 (EQH16_07760) | - | 1454333..1454545 (-) | 213 | WP_000393349.1 | crAss001_48 related protein | - |
| EQH16_RS07385 | - | 1454690..1454863 (-) | 174 | WP_000379086.1 | hypothetical protein | - |
| EQH16_RS07390 (EQH16_07765) | - | 1455014..1456564 (-) | 1551 | WP_179127978.1 | minor capsid protein | - |
| EQH16_RS07395 (EQH16_07770) | - | 1456473..1457942 (-) | 1470 | WP_000285389.1 | phage portal protein | - |
| EQH16_RS07400 (EQH16_07775) | - | 1457954..1459252 (-) | 1299 | WP_050315490.1 | PBSX family phage terminase large subunit | - |
| EQH16_RS07405 (EQH16_07780) | - | 1459230..1459730 (-) | 501 | WP_078133928.1 | terminase small subunit | - |
| EQH16_RS07410 (EQH16_07785) | - | 1460124..1460585 (-) | 462 | WP_001030245.1 | DUF1492 domain-containing protein | - |
| EQH16_RS07415 (EQH16_07790) | - | 1460660..1460974 (-) | 315 | WP_050236431.1 | hypothetical protein | - |
| EQH16_RS07420 (EQH16_07795) | - | 1460995..1461174 (-) | 180 | WP_001042650.1 | hypothetical protein | - |
| EQH16_RS11320 (EQH16_07800) | - | 1461167..1461235 (-) | 69 | WP_223842487.1 | YopX family protein | - |
| EQH16_RS07425 | - | 1461235..1461405 (-) | 171 | WP_168956836.1 | hypothetical protein | - |
| EQH16_RS07430 (EQH16_07805) | - | 1461398..1461634 (-) | 237 | WP_050236430.1 | DUF3310 domain-containing protein | - |
| EQH16_RS07435 (EQH16_07810) | - | 1461655..1462026 (-) | 372 | WP_050085308.1 | hypothetical protein | - |
| EQH16_RS07440 (EQH16_07815) | - | 1462023..1462235 (-) | 213 | WP_000160160.1 | hypothetical protein | - |
| EQH16_RS07445 (EQH16_07820) | - | 1462236..1462736 (-) | 501 | WP_001021770.1 | DUF1642 domain-containing protein | - |
| EQH16_RS07450 (EQH16_07825) | - | 1462738..1463052 (-) | 315 | WP_050393734.1 | hypothetical protein | - |
| EQH16_RS07455 (EQH16_07830) | - | 1463315..1463542 (-) | 228 | WP_226962077.1 | hypothetical protein | - |
| EQH16_RS07460 | - | 1463542..1463694 (-) | 153 | WP_000122747.1 | hypothetical protein | - |
| EQH16_RS07465 (EQH16_07835) | - | 1463988..1465331 (-) | 1344 | WP_050315477.1 | virulence-associated E family protein | - |
| EQH16_RS07470 (EQH16_07840) | - | 1465334..1466155 (-) | 822 | WP_001823578.1 | bifunctional DNA primase/polymerase | - |
| EQH16_RS07475 (EQH16_07845) | - | 1466328..1466834 (-) | 507 | WP_000054342.1 | hypothetical protein | - |
| EQH16_RS07480 (EQH16_07850) | - | 1466854..1467681 (-) | 828 | WP_000885996.1 | AAA family ATPase | - |
| EQH16_RS07485 (EQH16_07855) | - | 1467681..1467998 (-) | 318 | WP_001044592.1 | hypothetical protein | - |
| EQH16_RS07490 (EQH16_07860) | - | 1468017..1469210 (-) | 1194 | WP_000028860.1 | DEAD/DEAH box helicase family protein | - |
| EQH16_RS07495 (EQH16_07865) | - | 1469173..1469658 (-) | 486 | WP_000696056.1 | hypothetical protein | - |
| EQH16_RS07500 (EQH16_07870) | - | 1469658..1470008 (-) | 351 | WP_224757118.1 | hypothetical protein | - |
| EQH16_RS07505 (EQH16_07875) | - | 1470017..1470499 (-) | 483 | WP_000157807.1 | siphovirus Gp157 family protein | - |
| EQH16_RS07510 (EQH16_07880) | - | 1470492..1471214 (-) | 723 | WP_000544344.1 | HNH endonuclease signature motif containing protein | - |
| EQH16_RS07515 (EQH16_07885) | - | 1471228..1471458 (-) | 231 | WP_000252079.1 | hypothetical protein | - |
| EQH16_RS07520 (EQH16_07890) | - | 1471459..1471800 (-) | 342 | WP_000189401.1 | hypothetical protein | - |
| EQH16_RS07525 (EQH16_07895) | - | 1471812..1472003 (-) | 192 | WP_000970850.1 | hypothetical protein | - |
| EQH16_RS07530 (EQH16_07900) | - | 1472000..1472194 (-) | 195 | WP_001050924.1 | hypothetical protein | - |
| EQH16_RS07535 (EQH16_07905) | - | 1472191..1472463 (-) | 273 | WP_000388508.1 | hypothetical protein | - |
| EQH16_RS07540 | - | 1472543..1472686 (-) | 144 | WP_000389590.1 | hypothetical protein | - |
| EQH16_RS07545 (EQH16_07910) | - | 1472804..1473025 (+) | 222 | WP_000041096.1 | hypothetical protein | - |
| EQH16_RS07550 (EQH16_07915) | - | 1473139..1473330 (-) | 192 | WP_001112859.1 | DNA-binding protein | - |
| EQH16_RS07555 (EQH16_07920) | - | 1473395..1473634 (+) | 240 | WP_000142893.1 | hypothetical protein | - |
| EQH16_RS07560 (EQH16_07925) | - | 1474052..1474405 (+) | 354 | WP_000493110.1 | helix-turn-helix domain-containing protein | - |
| EQH16_RS07565 (EQH16_07930) | - | 1474407..1474829 (+) | 423 | WP_000181886.1 | hypothetical protein | - |
| EQH16_RS07570 (EQH16_07935) | - | 1474833..1475312 (+) | 480 | WP_001113481.1 | hypothetical protein | - |
| EQH16_RS07575 (EQH16_07940) | - | 1475333..1475713 (+) | 381 | WP_000151193.1 | ImmA/IrrE family metallo-endopeptidase | - |
| EQH16_RS07580 (EQH16_07945) | - | 1475855..1476982 (+) | 1128 | WP_000266847.1 | site-specific integrase | - |
| EQH16_RS07585 (EQH16_07950) | whiA | 1477070..1477981 (-) | 912 | WP_000011306.1 | DNA-binding protein WhiA | - |
| EQH16_RS07590 (EQH16_07955) | - | 1477978..1478955 (-) | 978 | WP_001231067.1 | YvcK family protein | - |
| EQH16_RS07595 (EQH16_07960) | rapZ | 1478952..1479842 (-) | 891 | WP_000163035.1 | RNase adapter RapZ | - |
| EQH16_RS07600 (EQH16_07965) | - | 1479894..1480274 (-) | 381 | WP_001140412.1 | RidA family protein | - |
| EQH16_RS07605 (EQH16_07970) | yihA | 1480285..1480872 (-) | 588 | WP_000422599.1 | ribosome biogenesis GTP-binding protein YihA/YsxC | - |
| EQH16_RS07610 (EQH16_07975) | clpX | 1480881..1482113 (-) | 1233 | WP_000106346.1 | ATP-dependent Clp protease ATP-binding subunit ClpX | Regulator |
| EQH16_RS07615 (EQH16_07980) | - | 1482145..1482315 (-) | 171 | WP_000442275.1 | hypothetical protein | - |
| EQH16_RS07620 (EQH16_07985) | - | 1482315..1482821 (-) | 507 | WP_000162486.1 | dihydrofolate reductase | - |
| EQH16_RS07625 (EQH16_07990) | - | 1482951..1483469 (-) | 519 | WP_000229874.1 | DNA starvation/stationary phase protection protein | - |
| EQH16_RS07630 (EQH16_07995) | lytC | 1483965..1485469 (-) | 1505 | Protein_1534 | choline binding-anchored murein hydrolase LytC | - |
| EQH16_RS07635 (EQH16_08000) | tpiA | 1485507..1486265 (-) | 759 | WP_000087897.1 | triose-phosphate isomerase | - |
| EQH16_RS07640 (EQH16_08005) | - | 1486363..1487040 (-) | 678 | WP_000221604.1 | DnaD domain-containing protein | - |
| EQH16_RS07645 (EQH16_08010) | metA | 1487049..1487993 (-) | 945 | WP_001122713.1 | homoserine O-succinyltransferase | - |
| EQH16_RS07650 (EQH16_08015) | - | 1488188..1488700 (-) | 513 | WP_001049325.1 | adenine phosphoribosyltransferase | - |
| EQH16_RS07655 (EQH16_08020) | - | 1488788..1489546 (-) | 759 | WP_001287230.1 | class I SAM-dependent methyltransferase | - |
| EQH16_RS07660 | - | 1489754..1489900 (+) | 147 | WP_000403100.1 | hypothetical protein | - |
| EQH16_RS07665 (EQH16_08025) | - | 1490047..1491177 (-) | 1131 | WP_000229959.1 | ABC transporter ATP-binding protein | - |
Sequence
Protein
Download Length: 410 a.a. Molecular weight: 45798.35 Da Isoelectric Point: 4.4550
>NTDB_id=338623 EQH16_RS07610 WP_000106346.1 1480881..1482113(-) (clpX) [Streptococcus pneumoniae strain TVO_1901921]
MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQEIIREELVEEVLADLSEVPKPIELLHILNHYVIGQDR
AKRALAVAVYNHYKRINFHDTREESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPQQEMIQVDT
KNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAIDENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVR
ILKEPRNALVKQYQTLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLVRITKETVD
GTDKPILETA
MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQEIIREELVEEVLADLSEVPKPIELLHILNHYVIGQDR
AKRALAVAVYNHYKRINFHDTREESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPQQEMIQVDT
KNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAIDENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVR
ILKEPRNALVKQYQTLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLVRITKETVD
GTDKPILETA
Nucleotide
Download Length: 1233 bp
>NTDB_id=338623 EQH16_RS07610 WP_000106346.1 1480881..1482113(-) (clpX) [Streptococcus pneumoniae strain TVO_1901921]
ATGTCTACAAATAGAAAAAATGATATGATGGTTTATTGCTCATTTTGTGGCAAAAACCAAGAAGAAGTACAAAAAATAAT
TGCTGGCAACAATGCTTTTATTTGTAATGAATGCGTGGAGTTAGCTCAGGAAATCATTCGAGAAGAATTGGTTGAGGAAG
TCTTGGCAGACTTGTCTGAGGTGCCAAAACCAATTGAACTCCTCCATATCTTGAACCACTATGTAATTGGTCAAGATCGT
GCCAAGCGTGCCTTGGCAGTGGCGGTTTATAACCACTACAAACGCATCAATTTCCACGATACACGCGAAGAGTCAGAAGA
TGTGGATTTGCAGAAGTCAAACATTTTGATGATTGGCCCAACTGGTTCAGGGAAAACTTTCCTTGCCCAGACCTTGGCTA
AGAGCTTGAATGTGCCTTTTGCTATTGCGGATGCGACAGCTCTGACGGAGGCTGGTTATGTGGGTGAGGACGTGGAAAAT
ATCCTCCTCAAACTCTTGCAGGTTGCTGACTTTAACATCGAACGTGCAGAGCGTGGCATTATCTATGTGGATGAAATTGA
CAAGATTGCCAAGAAGAGTGAGAATGTGTCTATCACACGTGATGTTTCTGGTGAAGGGGTGCAACAAGCCCTTCTCAAGA
TTATCGAGGGAACTGTTGCTAGCGTGCCGCCTCAAGGTGGACGCAAACATCCACAACAAGAGATGATTCAAGTGGATACA
AAAAATATCCTCTTCATCGTGGGTGGTGCTTTTGATGGTATTGAAGAAATTGTCAAACAACGTCTGGGTGAAAAAGTCAT
CGGATTTGGTCAAAATAATAAGGCGATTGACGAAAACAGCTCATATATGCAAGAAATCATCGCTGAAGACATTCAAAAAT
TTGGTATTATCCCTGAGTTGATTGGACGCTTGCCTGTTTTTGCGGCTCTTGAGCAATTGACCGTTGATGACTTGGTTCGC
ATCTTGAAAGAGCCAAGAAATGCCTTGGTGAAACAATACCAAACTTTGCTTTCTTATGATGATGTTGAGTTGGAATTTGA
CGACGAAGCCCTTCAAGAGATTGCTAATAAAGCAATCGAACGGAAGACAGGGGCGCGTGGACTTCGCTCCATTATCGAAG
AAACCATGCTAGATGTTATGTTTGAGGTGCCGAGTCAGGAAAATGTGAAATTGGTTCGCATCACTAAAGAAACTGTCGAT
GGAACGGATAAACCGATCCTAGAAACAGCCTAG
ATGTCTACAAATAGAAAAAATGATATGATGGTTTATTGCTCATTTTGTGGCAAAAACCAAGAAGAAGTACAAAAAATAAT
TGCTGGCAACAATGCTTTTATTTGTAATGAATGCGTGGAGTTAGCTCAGGAAATCATTCGAGAAGAATTGGTTGAGGAAG
TCTTGGCAGACTTGTCTGAGGTGCCAAAACCAATTGAACTCCTCCATATCTTGAACCACTATGTAATTGGTCAAGATCGT
GCCAAGCGTGCCTTGGCAGTGGCGGTTTATAACCACTACAAACGCATCAATTTCCACGATACACGCGAAGAGTCAGAAGA
TGTGGATTTGCAGAAGTCAAACATTTTGATGATTGGCCCAACTGGTTCAGGGAAAACTTTCCTTGCCCAGACCTTGGCTA
AGAGCTTGAATGTGCCTTTTGCTATTGCGGATGCGACAGCTCTGACGGAGGCTGGTTATGTGGGTGAGGACGTGGAAAAT
ATCCTCCTCAAACTCTTGCAGGTTGCTGACTTTAACATCGAACGTGCAGAGCGTGGCATTATCTATGTGGATGAAATTGA
CAAGATTGCCAAGAAGAGTGAGAATGTGTCTATCACACGTGATGTTTCTGGTGAAGGGGTGCAACAAGCCCTTCTCAAGA
TTATCGAGGGAACTGTTGCTAGCGTGCCGCCTCAAGGTGGACGCAAACATCCACAACAAGAGATGATTCAAGTGGATACA
AAAAATATCCTCTTCATCGTGGGTGGTGCTTTTGATGGTATTGAAGAAATTGTCAAACAACGTCTGGGTGAAAAAGTCAT
CGGATTTGGTCAAAATAATAAGGCGATTGACGAAAACAGCTCATATATGCAAGAAATCATCGCTGAAGACATTCAAAAAT
TTGGTATTATCCCTGAGTTGATTGGACGCTTGCCTGTTTTTGCGGCTCTTGAGCAATTGACCGTTGATGACTTGGTTCGC
ATCTTGAAAGAGCCAAGAAATGCCTTGGTGAAACAATACCAAACTTTGCTTTCTTATGATGATGTTGAGTTGGAATTTGA
CGACGAAGCCCTTCAAGAGATTGCTAATAAAGCAATCGAACGGAAGACAGGGGCGCGTGGACTTCGCTCCATTATCGAAG
AAACCATGCTAGATGTTATGTTTGAGGTGCCGAGTCAGGAAAATGTGAAATTGGTTCGCATCACTAAAGAAACTGTCGAT
GGAACGGATAAACCGATCCTAGAAACAGCCTAG
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| clpX | Streptococcus mutans UA159 |
86.585 |
100 |
0.866 |
| clpX | Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819 |
57.214 |
98.049 |
0.561 |