Detailed information NTG0338486

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: EQH18_RS09115
• Genome accession: NZ_CP035262
• Coordinates: 1825563..1826600 (-)
• Length: 345 a.a.
• NCBI ID: WP_061750848.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain TVO_1901923
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1820563..1831600

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQH18_RS09090 (EQH18_09605)	-	1821302..1822633 (-)	1332	WP_000390043.1	hemolysin family protein	-
EQH18_RS09095 (EQH18_09610)	endA	1822924..1823748 (-)	825	WP_001036789.1	DNA-entry nuclease EndA	Machinery gene
EQH18_RS09100 (EQH18_09615)	-	1823787..1823975 (-)	189	WP_001813390.1	DNA-directed RNA polymerase subunit beta	-
EQH18_RS09105 (EQH18_09620)	murA	1823968..1825251 (-)	1284	WP_000358028.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
EQH18_RS09110 (EQH18_09625)	-	1825275..1825505 (-)	231	WP_000250392.1	DUF1146 family protein	-
EQH18_RS09115 (EQH18_09630)	sepM	1825563..1826600 (-)	1038	WP_061750848.1	SepM family pheromone-processing serine protease	Regulator
EQH18_RS09120 (EQH18_09635)	coaD	1826584..1827072 (-)	489	WP_001280736.1	pantetheine-phosphate adenylyltransferase	-
EQH18_RS09125 (EQH18_09640)	rsmD	1827062..1827601 (-)	540	WP_000706966.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
EQH18_RS09130 (EQH18_09645)	asnA	1827666..1828658 (-)	993	WP_000747993.1	aspartate--ammonia ligase	-
EQH18_RS09135 (EQH18_09655)	-	1828770..1829453 (-)	684	WP_001016917.1	Bax inhibitor-1/YccA family protein	-
EQH18_RS09140 (EQH18_09660)	-	1829509..1830249 (-)	741	WP_000152680.1	RNA methyltransferase	-
EQH18_RS09145 (EQH18_09665)	-	1830283..1830561 (+)	279	WP_001174613.1	acylphosphatase	-
EQH18_RS09150 (EQH18_09670)	yidC	1830639..1831565 (+)	927	WP_000835955.1	membrane protein insertase YidC	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37492.51 Da
• Isoelectric Point: 5.0724

>NTDB_id=338486 EQH18_RS09115 WP_061750848.1 1825563..1826600(-) (sepM) [Streptococcus pneumoniae strain TVO_1901923]
MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLKVNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFT
DIRSAQETTGGSSDVEFLRINQFYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVISNVPISFSTAGIGGPSAGLMFSL
AIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGIDKKVVASARAGAAIFFAPDNPVSEEEQKAHPDAKNNYQTALEAAK
TIKTDMKIVPVKTLQDAIDYLKNSP

Nucleotide

• Length: 1038 bp

>NTDB_id=338486 EQH18_RS09115 WP_061750848.1 1825563..1826600(-) (sepM) [Streptococcus pneumoniae strain TVO_1901923]
ATGAAAAAAAAGATTAGATGGCCCTTATACGTCATTGCGGCCTTGATTGTGACTTTCTTGGCATTTGTAGTGCCCTTGCC
TTATTATATAGAGGTTCCAGGTGGTTCGGAAGATATTCGCCAAGTCCTTAAAGTAAATGACACAGAAGATAAGGAAGCTG
GTGCCTATCAATTCGTTACGGTTGGTGTTCAACATGCCACTTTAGCTCATATGATTTATGCTTGGTTGACACCTTTTACA
GATATTCGTAGTGCTCAGGAGACTACAGGTGGTTCTTCCGATGTTGAATTTCTGCGAATCAATCAATTCTACATGCAAAC
ATCGCAAAATATGGCCAAGTATCAAGGACTAAAAACAGCTGGTAAGGATATCGAACTCAAGTACTTTGGAGTTTATGTTT
TGAATGTGACGGATAATTCAACCTTTAAAGGGATTCTCAATATCTCTGATACGGTCACAGCAGTCAATGATCAGACCTTT
GATAGTTCCAAAGACTTGATTGATTACGTCAGTTCTCAAAAATTAGGGGATTCCGTCAAGGTCACCTATGAAGAGGATGG
GCAAACCAAGTCTGCAGAAGGAAAAATCATCACCTTGGAAAATGGCAAAAATGGAATTGGAATCGGCTTGATTGACCGTA
CAGAGGTAATCAGCAATGTCCCAATTAGCTTTTCAACAGCTGGTATTGGCGGTCCAAGTGCTGGTCTCATGTTTAGTCTA
GCTATCTATACTCAAATAGCTCACCCAGATCTTCGTAATGGTCGTATTGTTGCCGGTACAGGTACCATTGACCGCGATGG
TAATGTGGGAGACATTGGAGGTATTGATAAGAAGGTTGTAGCTTCGGCTAGGGCAGGTGCTGCTATTTTCTTTGCTCCTG
ATAACCCTGTTAGCGAAGAAGAACAAAAGGCGCATCCGGACGCGAAAAACAACTACCAAACAGCCCTAGAAGCGGCTAAA
ACAATCAAGACGGATATGAAAATCGTGCCCGTTAAAACCCTACAAGATGCGATTGATTACTTGAAAAACAGTCCCTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (130-193)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (230-296)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	59.706	98.551	0.588