Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   EQH19_RS09165 Genome accession   NZ_CP035261
Coordinates   1799761..1800585 (-) Length   274 a.a.
NCBI ID   WP_001036781.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain TVO_1901924     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 1794761..1805585
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH19_RS09160 (EQH19_09680) - 1798139..1799470 (-) 1332 WP_000390042.1 hemolysin family protein -
  EQH19_RS09165 (EQH19_09685) endA 1799761..1800585 (-) 825 WP_001036781.1 DNA-entry nuclease EndA Machinery gene
  EQH19_RS09170 (EQH19_09690) - 1800624..1800812 (-) 189 WP_001036519.1 DNA-directed RNA polymerase subunit beta -
  EQH19_RS09175 (EQH19_09695) murA 1800805..1802088 (-) 1284 WP_000358028.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  EQH19_RS09180 (EQH19_09700) - 1802112..1802342 (-) 231 WP_000250384.1 DUF1146 family protein -
  EQH19_RS09185 (EQH19_09705) sepM 1802400..1803437 (-) 1038 WP_000727277.1 SepM family pheromone-processing serine protease Regulator
  EQH19_RS09190 (EQH19_09710) coaD 1803421..1803909 (-) 489 WP_001280769.1 pantetheine-phosphate adenylyltransferase -
  EQH19_RS09195 (EQH19_09715) rsmD 1803899..1804438 (-) 540 WP_001819515.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  EQH19_RS09200 (EQH19_09720) asnA 1804503..1805495 (-) 993 WP_000747993.1 aspartate--ammonia ligase -

Sequence

Protein


Download         Length: 274 a.a.        Molecular weight: 29945.70 Da        Isoelectric Point: 10.1700

>NTDB_id=338407 EQH19_RS09165 WP_001036781.1 1799761..1800585(-) (endA) [Streptococcus pneumoniae strain TVO_1901924]
MNKKTRQTLIGLLVLLLLSTGSYYIKQMQSAPNSPKTKLSQKKQAPEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIV
NGNKTNLDAKVSSKPYADNKTKTVGKETVPTVANALLSKATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRVRYRVTLYYASNEDLVPSASQIE
AKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ

Nucleotide


Download         Length: 825 bp        

>NTDB_id=338407 EQH19_RS09165 WP_001036781.1 1799761..1800585(-) (endA) [Streptococcus pneumoniae strain TVO_1901924]
ATGAACAAAAAAACAAGACAGACACTAATCGGACTGCTAGTGTTATTGCTTTTGTCTACAGGGAGCTATTATATCAAGCA
GATGCAGTCGGCACCTAATAGTCCTAAAACCAAGCTTAGTCAGAAAAAACAAGCGCCTGAAGCTCCTAGTCAAGCATTGG
CAGAGAGTGTCTTAACAGACGCAGTCAAGAGTCAAATAAAGGGGAGTCTGGAGTGGAATGGCTCAGGTGCTTTTATCGTC
AATGGTAATAAAACAAATCTAGATGCCAAGGTTTCAAGTAAGCCCTACGCTGACAATAAAACAAAGACAGTGGGCAAGGA
AACTGTTCCAACCGTAGCTAATGCCCTCTTGTCTAAGGCCACTCGTCAGTACAAGAATCGTAAAGAAACTGGGAATGGTT
CAACTTCTTGGACTCCTCCAGGTTGGCATCAGGTCAAGAATCTAAAGGGCTCTTATACCCATGCAGTCGATAGAGGTCAT
TTGTTAGGCTATGCCTTAATCGGTGGTTTGGATGGTTTTGATGCCTCAACAAGCAATCCTAAAAACATTGCTGTTCAGAC
AGCCTGGGCAAATCAGGCACAAGCCGAGTATTCGACTGGTCAAAACTACTATGAAAGCAAGGTGCGTAAAGCCTTGGACC
AAAACAAGCGTGTCCGTTACCGTGTAACCCTTTACTACGCTTCAAACGAGGATTTAGTTCCCTCAGCTTCACAGATTGAA
GCCAAGTCTTCGGATGGAGAATTGGAATTCAATGTTCTAGTTCCCAATGTTCAAAAGGGACTTCAACTGGATTACCGAAC
TGGAGAAGTAACTGTAACTCAGTAA

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(75-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

98.905

100

0.989
  endA Streptococcus pneumoniae D39

98.905

100

0.989
  endA Streptococcus pneumoniae R6

98.905

100

0.989
  endA Streptococcus pneumoniae TIGR4

98.905

100

0.989

Multiple sequence alignment