Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   EQH20_RS08635 Genome accession   NZ_CP035260
Coordinates   1711296..1712120 (-) Length   274 a.a.
NCBI ID   WP_001036781.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain TVO_1901925     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 1706296..1717120
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH20_RS08630 (EQH20_09120) - 1709674..1711005 (-) 1332 WP_000390042.1 hemolysin family protein -
  EQH20_RS08635 (EQH20_09125) endA 1711296..1712120 (-) 825 WP_001036781.1 DNA-entry nuclease EndA Machinery gene
  EQH20_RS08640 (EQH20_09130) - 1712159..1712347 (-) 189 WP_001036519.1 DNA-directed RNA polymerase subunit beta -
  EQH20_RS08645 (EQH20_09135) murA 1712340..1713623 (-) 1284 WP_000358028.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  EQH20_RS08650 (EQH20_09140) - 1713647..1713877 (-) 231 WP_000250384.1 DUF1146 family protein -
  EQH20_RS08655 (EQH20_09145) sepM 1713935..1714972 (-) 1038 WP_000727277.1 SepM family pheromone-processing serine protease Regulator
  EQH20_RS08660 (EQH20_09150) coaD 1714956..1715444 (-) 489 WP_001280769.1 pantetheine-phosphate adenylyltransferase -
  EQH20_RS08665 (EQH20_09155) rsmD 1715434..1715973 (-) 540 WP_001819515.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  EQH20_RS08670 (EQH20_09160) asnA 1716038..1717030 (-) 993 WP_000747993.1 aspartate--ammonia ligase -

Sequence

Protein


Download         Length: 274 a.a.        Molecular weight: 29945.70 Da        Isoelectric Point: 10.1700

>NTDB_id=338330 EQH20_RS08635 WP_001036781.1 1711296..1712120(-) (endA) [Streptococcus pneumoniae strain TVO_1901925]
MNKKTRQTLIGLLVLLLLSTGSYYIKQMQSAPNSPKTKLSQKKQAPEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIV
NGNKTNLDAKVSSKPYADNKTKTVGKETVPTVANALLSKATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRVRYRVTLYYASNEDLVPSASQIE
AKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ

Nucleotide


Download         Length: 825 bp        

>NTDB_id=338330 EQH20_RS08635 WP_001036781.1 1711296..1712120(-) (endA) [Streptococcus pneumoniae strain TVO_1901925]
ATGAACAAAAAAACAAGACAGACACTAATCGGACTGCTAGTGTTATTGCTTTTGTCTACAGGGAGCTATTATATCAAGCA
GATGCAGTCGGCACCTAATAGTCCTAAAACCAAGCTTAGTCAGAAAAAACAAGCGCCTGAAGCTCCTAGTCAAGCATTGG
CAGAGAGTGTCTTAACAGACGCAGTCAAGAGTCAAATAAAGGGGAGTCTGGAGTGGAATGGCTCAGGTGCTTTTATCGTC
AATGGTAATAAAACAAATCTAGATGCCAAGGTTTCAAGTAAGCCCTACGCTGACAATAAAACAAAGACAGTGGGCAAGGA
AACTGTTCCAACCGTAGCTAATGCCCTCTTGTCTAAGGCCACTCGTCAGTACAAGAATCGTAAAGAAACTGGGAATGGTT
CAACTTCTTGGACTCCTCCAGGTTGGCATCAGGTCAAGAATCTAAAGGGCTCTTATACCCATGCAGTCGATAGAGGTCAT
TTGTTAGGCTATGCCTTAATCGGTGGTTTGGATGGTTTTGATGCCTCAACAAGCAATCCTAAAAACATTGCTGTTCAGAC
AGCCTGGGCAAATCAGGCACAAGCCGAGTATTCGACTGGTCAAAACTACTATGAAAGCAAGGTGCGTAAAGCCTTGGACC
AAAACAAGCGTGTCCGTTACCGTGTAACCCTTTACTACGCTTCAAACGAGGATTTAGTTCCCTCAGCTTCACAGATTGAA
GCCAAGTCTTCGGATGGAGAATTGGAATTCAATGTTCTAGTTCCCAATGTTCAAAAGGGACTTCAACTGGATTACCGAAC
TGGAGAAGTAACTGTAACTCAGTAA

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(75-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

98.905

100

0.989
  endA Streptococcus pneumoniae D39

98.905

100

0.989
  endA Streptococcus pneumoniae R6

98.905

100

0.989
  endA Streptococcus pneumoniae TIGR4

98.905

100

0.989

Multiple sequence alignment