Detailed information NTG0338243

Bioinformatically predicted

Overview

• Name: amiE
• Type: Regulator
• Locus tag: EQH21_RS08615
• Genome accession: NZ_CP035259
• Coordinates: 1717921..1718988 (-)
• Length: 355 a.a.
• NCBI ID: WP_000159554.1
• Uniprot ID: A0A062WMA1
• Organism: Streptococcus pneumoniae strain TVO_1901926
• Function: internalize XIP (predicted from homology) Competence regulation

Genomic Context

Location: 1712921..1723988

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQH21_RS08590 (EQH21_09035)	treR	1713092..1713802 (+)	711	WP_000760673.1	trehalose operon repressor	Regulator
EQH21_RS08595 (EQH21_09040)	-	1713835..1714638 (-)	804	WP_000157664.1	ABC transporter ATP-binding protein	-
EQH21_RS08600 (EQH21_09045)	-	1714651..1715544 (-)	894	WP_001012093.1	ABC transporter permease	-
EQH21_RS08605 (EQH21_09050)	-	1715556..1716365 (-)	810	Protein_1730	ABC transporter substrate-binding protein	-
EQH21_RS08610 (EQH21_09055)	amiF	1716984..1717910 (-)	927	WP_001291293.1	ATP-binding cassette domain-containing protein	Regulator
EQH21_RS08615 (EQH21_09060)	amiE	1717921..1718988 (-)	1068	WP_000159554.1	ABC transporter ATP-binding protein	Regulator
EQH21_RS08620 (EQH21_09065)	amiD	1718997..1719923 (-)	927	WP_000103700.1	oligopeptide ABC transporter permease OppC	Regulator
EQH21_RS08625 (EQH21_09070)	amiC	1719923..1721419 (-)	1497	WP_000759905.1	ABC transporter permease	Regulator
EQH21_RS08630 (EQH21_09075)	amiA3	1721486..1723465 (-)	1980	WP_000742236.1	peptide ABC transporter substrate-binding protein	Regulator

Sequence

Protein

• Length: 355 a.a.
• Molecular weight: 39490.09 Da
• Isoelectric Point: 4.8727

>NTDB_id=338243 EQH21_RS08615 WP_000159554.1 1717921..1718988(-) (amiE) [Streptococcus pneumoniae strain TVO_1901926]
MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALVGESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDL
TALSSHKDWEQIRGAKIATIFQDPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITHDLGVVASIADKVAVMYAGEIVE
YGTVEEVFYDPRHPYTWSLLSSLPQLADDKGDLYSIPGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAK
TWLLHEDAPKVEKPAVIANLHDKIREKMGFAHLAD

Nucleotide

• Length: 1068 bp

>NTDB_id=338243 EQH21_RS08615 WP_000159554.1 1717921..1718988(-) (amiE) [Streptococcus pneumoniae strain TVO_1901926]
ATGACAAAAGAAAAAAATGTAATTTTGACTGCTCGCGATATTGTCGTGGAATTTGACGTTCGTGACAAAGTATTGACAGC
CATTCGCGGCGTTTCCCTTGAACTAGTCGAAGGAGAAGTATTAGCCTTGGTAGGTGAGTCAGGATCAGGTAAATCTGTTT
TGACAAAGACCTTCACAGGTATGCTCGAAGAAAATGGTCGTATTGCCCAAGGTAGTATTGACTACCGTGGTCAGGACTTG
ACAGCTTTATCTTCTCACAAGGATTGGGAACAAATTCGTGGTGCTAAGATTGCGACTATCTTCCAGGACCCAATGACTAG
TTTGGACCCCATTAAAACAATTGGTAGTCAGATTACAGAAGTTATTGTAAAACACCAAGGAAAAACAGCTAAAGAAGCGA
AAGAATTGGCCATTGACTACATGAATAAGGTTGGCATTCCAGACGCAGATAGACGTTTTAATGAATACCCATTCCAATAT
TCTGGAGGAATGCGTCAACGTATCGTTATTGCGATTGCCCTTGCCTGCCGACCTGATGTCTTGATCTGTGATGAGCCAAC
AACTGCCTTGGATGTAACTATTCAAGCTCAGATTATTGATTTGCTAAAATCTTTACAAAACGAGTATCATTTCACAACAA
TCTTTATTACCCACGACCTTGGTGTGGTGGCAAGTATTGCGGATAAGGTAGCGGTTATGTATGCAGGAGAAATCGTTGAG
TATGGAACGGTTGAGGAAGTCTTCTATGACCCTCGCCATCCATATACATGGAGTCTCTTGTCTAGCTTGCCTCAGCTTGC
TGATGATAAAGGGGATCTTTACTCAATCCCAGGAACACCTCCGTCACTTTATACTGACCTGAAAGGGGATGCTTTTGCCT
TGCGTTCTGACTACGCAATGCAGATTGACTTCGAACAAAAAGCTCCTCAATTCTCAGTATCAGAGACACATTGGGCTAAA
ACTTGGCTTCTTCATGAGGATGCTCCAAAAGTAGAAAAACCAGCTGTGATTGCAAATCTCCATGATAAAATCCGTGAAAA
AATGGGATTTGCCCATCTGGCTGACTAG

Domains

Predicted by InterproScan.

• Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY) (239-301)

• ABC transporter (ABC_tran) (29-187)

3D structure

• AlphaFold DB: A0A062WMA1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
amiE	Streptococcus salivarius strain HSISS4	88.169	100	0.882
amiE	Streptococcus thermophilus LMG 18311	86.479	100	0.865
amiE	Streptococcus thermophilus LMD-9	86.479	100	0.865
oppD	Streptococcus mutans UA159	54.545	99.155	0.541