Detailed information NTG0337777

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: EQH29_RS09065
• Genome accession: NZ_CP035251
• Coordinates: 1812932..1813969 (-)
• Length: 345 a.a.
• NCBI ID: WP_000727276.1
• Uniprot ID: A0AAQ2ZXI6
• Organism: Streptococcus pneumoniae strain TVO_1901935
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1807932..1818969

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQH29_RS09040 (EQH29_09600)	-	1808671..1810002 (-)	1332	WP_000390039.1	hemolysin family protein	-
EQH29_RS09045 (EQH29_09605)	endA	1810293..1811117 (-)	825	WP_047474853.1	DNA-entry nuclease EndA	Machinery gene
EQH29_RS09050 (EQH29_09610)	-	1811156..1811344 (-)	189	WP_001813390.1	DNA-directed RNA polymerase subunit beta	-
EQH29_RS09055 (EQH29_09615)	murA	1811337..1812620 (-)	1284	WP_000358028.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
EQH29_RS09060 (EQH29_09620)	-	1812644..1812874 (-)	231	WP_000250392.1	DUF1146 family protein	-
EQH29_RS09065 (EQH29_09625)	sepM	1812932..1813969 (-)	1038	WP_000727276.1	SepM family pheromone-processing serine protease	Regulator
EQH29_RS09070 (EQH29_09630)	coaD	1813953..1814441 (-)	489	WP_238094692.1	pantetheine-phosphate adenylyltransferase	-
EQH29_RS09075 (EQH29_09635)	rsmD	1814431..1814970 (-)	540	WP_000706962.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
EQH29_RS09080 (EQH29_09640)	asnA	1815035..1816027 (-)	993	WP_000747993.1	aspartate--ammonia ligase	-
EQH29_RS09085 (EQH29_09650)	-	1816139..1816822 (-)	684	WP_001016913.1	Bax inhibitor-1/YccA family protein	-
EQH29_RS09090 (EQH29_09655)	-	1816878..1817618 (-)	741	WP_000152701.1	RNA methyltransferase	-
EQH29_RS09095 (EQH29_09660)	-	1817652..1817930 (+)	279	WP_001174613.1	acylphosphatase	-
EQH29_RS09100 (EQH29_09665)	yidC	1818008..1818934 (+)	927	WP_000835948.1	membrane protein insertase YidC	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37553.61 Da
• Isoelectric Point: 5.0724

>NTDB_id=337777 EQH29_RS09065 WP_000727276.1 1812932..1813969(-) (sepM) [Streptococcus pneumoniae strain TVO_1901935]
MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLKVNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFT
DIRSAQETTGGSSDVEFMRINQFYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVISNVPISFSTAGIGGPSAGLMFSL
AIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGIDKKVVASARAGAAIFFAPDNPVSEEEQKAHLDAKNNYQTALEAAK
TIKTDMKIVPVKTLQDAIDYLKNNP

Nucleotide

• Length: 1038 bp

>NTDB_id=337777 EQH29_RS09065 WP_000727276.1 1812932..1813969(-) (sepM) [Streptococcus pneumoniae strain TVO_1901935]
ATGAAAAAAAAGATTAGATGGCCCTTATACGTCATTGCGGCCTTGATTGTGACTTTCTTGGCATTTGTAGTGCCCTTGCC
TTATTATATAGAGGTTCCAGGTGGTTCGGAAGATATTCGCCAAGTCCTTAAAGTAAATGACACAGAAGATAAGGAAGCTG
GTGCCTATCAATTCGTTACGGTTGGTGTTCAACATGCCACTTTAGCTCATATGATTTATGCTTGGTTGACACCTTTTACA
GATATTCGTAGTGCTCAGGAGACTACAGGTGGTTCTTCCGATGTTGAATTTATGCGAATCAATCAATTCTACATGCAAAC
ATCGCAAAATATGGCCAAGTATCAAGGACTAAAAACAGCTGGTAAGGATATCGAACTCAAGTACTTTGGAGTTTATGTTT
TGAATGTGACGGATAATTCAACCTTTAAAGGGATTCTCAATATCTCTGATACAGTCACAGCAGTCAATGATCAGACCTTT
GATAGTTCCAAAGACTTGATTGATTACGTCAGTTCTCAAAAATTAGGGGATTCCGTCAAGGTCACCTATGAAGAGGATGG
GCAAACCAAGTCTGCAGAAGGAAAGATTATCACCTTGGAAAATGGCAAAAATGGAATTGGAATCGGCTTGATTGACCGTA
CAGAGGTAATCAGCAATGTCCCAATTAGCTTTTCAACAGCTGGTATTGGCGGCCCAAGTGCTGGTCTCATGTTTAGTCTA
GCTATCTATACTCAAATAGCTCACCCAGATCTTCGTAATGGTCGTATTGTTGCCGGTACAGGTACCATTGACCGCGATGG
TAATGTGGGAGACATTGGAGGTATTGATAAGAAGGTTGTAGCTTCGGCTAGGGCAGGTGCTGCTATTTTCTTTGCTCCTG
ATAACCCTGTTAGCGAAGAAGAACAAAAGGCGCATCTGGACGCGAAAAACAACTACCAAACAGCCCTAGAAGCGGCTAAA
ACAATCAAGACGGATATGAAAATCGTGCCCGTTAAAACCCTACAAGATGCGATTGATTACTTGAAAAACAATCCCTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (130-193)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (230-296)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	59.357	99.13	0.588