Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   EQH29_RS01785 Genome accession   NZ_CP035251
Coordinates   343676..344365 (+) Length   229 a.a.
NCBI ID   WP_047474084.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain TVO_1901935     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 338676..349365
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH29_RS01760 (EQH29_01855) gpsB 338809..339138 (+) 330 WP_000146522.1 cell division regulator GpsB -
  EQH29_RS01770 (EQH29_01865) - 339624..340781 (+) 1158 WP_050230812.1 class I SAM-dependent RNA methyltransferase -
  EQH29_RS01775 (EQH29_01870) mapZ 340794..342164 (+) 1371 WP_000039301.1 mid-cell-anchored protein MapZ -
  EQH29_RS01780 (EQH29_01875) gndA 342240..343664 (+) 1425 WP_000158799.1 NADP-dependent phosphogluconate dehydrogenase -
  EQH29_RS01785 (EQH29_01880) covR 343676..344365 (+) 690 WP_047474084.1 response regulator transcription factor Regulator
  EQH29_RS01790 (EQH29_01885) - 344463..345359 (+) 897 WP_238094702.1 N-acetylmuramoyl-L-alanine amidase family protein -
  EQH29_RS01795 (EQH29_01890) - 345477..346709 (-) 1233 WP_000765684.1 MFS transporter -
  EQH29_RS01800 (EQH29_01895) - 346868..347338 (-) 471 WP_001809487.1 lanthionine synthetase LanC family protein -
  EQH29_RS01805 (EQH29_01900) - 347238..347576 (-) 339 WP_001820155.1 lanthionine synthetase LanC family protein -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26917.27 Da        Isoelectric Point: 7.3523

>NTDB_id=337732 EQH29_RS01785 WP_047474084.1 343676..344365(+) (covR) [Streptococcus pneumoniae strain TVO_1901935]
MGKRILLLEKERNLARFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLMLLNVNLGDMMAQDFAEKLSRTKPASVIMIL
DHWEDLQEELEVVQRFAVSYIYKPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=337732 EQH29_RS01785 WP_047474084.1 343676..344365(+) (covR) [Streptococcus pneumoniae strain TVO_1901935]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCGTTTTTTAAGTTTGGAACTCCAGAAAGAGCAGTA
TCGGGTTGATCTGGTAGAGGAGGGGCAAAAAGCCCTCTCCATGGCTCTTCAGACAGACTATGATTTGATGTTATTGAACG
TTAATCTGGGAGATATGATGGCTCAGGATTTTGCAGAAAAATTGAGTCGAACTAAACCTGCCTCAGTCATCATGATTTTA
GATCATTGGGAAGACTTGCAAGAAGAGCTGGAAGTTGTTCAGCGTTTTGCAGTTTCATACATTTATAAGCCAGTCCTTAT
CGAAAATCTGGTAGCGCGTATTTCGGCGATCTTCCGAGGTCGGGACTTCATTGATCAACACTGCAGTCTGATGAAAGTTC
CAAGGACCTACCGCAATCTTAGGATAGATGTTGAACATCACACGGTTTATCGTGGTGAAGAGATGATTGCTCTGACCCGC
CGTGAGTATGACCTTTTGGCGACACTTATGGGAAGCAAGAAAGTATTGACTCGTGAGCAATTGTTGGAAAGTGTTTGGAA
GTATGAAAGTGCGACCGAGACAAATATCGTAGATGTCTATATCCGCTATCTACGGAGCAAGCTTGATGTTAAAGGCCAAA
AAAGCTACATTAAAACCGTGCGTGGTGTTGGATATACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.261

100

0.485
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.522

100

0.467

Multiple sequence alignment