Detailed information NTG0337606

Bioinformatically predicted

Overview

• Name: amiE
• Type: Regulator
• Locus tag: EQH32_RS08715
• Genome accession: NZ_CP035248
• Coordinates: 1711640..1712707 (-)
• Length: 355 a.a.
• NCBI ID: WP_000159554.1
• Uniprot ID: A0A062WMA1
• Organism: Streptococcus pneumoniae strain TVO_1901939
• Function: internalize XIP (predicted from homology) Competence regulation

Genomic Context

Location: 1706640..1717707

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQH32_RS08695 (EQH32_09155)	-	1707141..1708018 (-)	878	Protein_1739	ABC transporter permease	-
EQH32_RS08700 (EQH32_09160)	-	1708063..1708839 (-)	777	Protein_1740	ABC transporter substrate-binding protein	-
EQH32_RS08705 (EQH32_09165)	-	1709393..1710346 (-)	954	WP_001155321.1	IS30-like element ISSpn8 family transposase	-
EQH32_RS08710 (EQH32_09170)	amiF	1710703..1711629 (-)	927	WP_001291293.1	ATP-binding cassette domain-containing protein	Regulator
EQH32_RS08715 (EQH32_09175)	amiE	1711640..1712707 (-)	1068	WP_000159554.1	ABC transporter ATP-binding protein	Regulator
EQH32_RS08720 (EQH32_09180)	amiD	1712716..1713642 (-)	927	WP_000103697.1	oligopeptide ABC transporter permease OppC	Regulator
EQH32_RS08725 (EQH32_09185)	amiC	1713642..1715138 (-)	1497	WP_000759902.1	ABC transporter permease	Regulator
EQH32_RS08730 (EQH32_09190)	amiA3	1715205..1717184 (-)	1980	WP_000742233.1	peptide ABC transporter substrate-binding protein	Regulator

Sequence

Protein

• Length: 355 a.a.
• Molecular weight: 39490.09 Da
• Isoelectric Point: 4.8727

>NTDB_id=337606 EQH32_RS08715 WP_000159554.1 1711640..1712707(-) (amiE) [Streptococcus pneumoniae strain TVO_1901939]
MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALVGESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDL
TALSSHKDWEQIRGAKIATIFQDPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITHDLGVVASIADKVAVMYAGEIVE
YGTVEEVFYDPRHPYTWSLLSSLPQLADDKGDLYSIPGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAK
TWLLHEDAPKVEKPAVIANLHDKIREKMGFAHLAD

Nucleotide

• Length: 1068 bp

>NTDB_id=337606 EQH32_RS08715 WP_000159554.1 1711640..1712707(-) (amiE) [Streptococcus pneumoniae strain TVO_1901939]
ATGACAAAAGAAAAAAATGTAATTTTGACTGCTCGCGATATTGTCGTGGAATTTGACGTTCGTGACAAAGTATTGACAGC
CATTCGCGGCGTTTCCCTTGAACTCGTTGAAGGAGAAGTATTAGCCTTGGTAGGTGAGTCAGGATCAGGTAAATCTGTTT
TGACAAAGACCTTCACAGGTATGCTCGAAGAAAATGGTCGCATTGCCCAAGGTAGTATTGACTACCGTGGTCAGGATTTG
ACAGCTTTATCTTCTCACAAGGATTGGGAACAAATTCGTGGTGCTAAGATTGCGACTATCTTCCAGGACCCAATGACTAG
TTTGGACCCCATTAAAACAATTGGTAGTCAGATTACAGAAGTTATTGTAAAACACCAAGGAAAAACAGCTAAAGAAGCGA
AAGAATTGGCCATTGACTACATGAATAAGGTTGGCATTCCAGACGCAGATAGACGTTTTAATGAATACCCATTCCAATAT
TCTGGAGGAATGCGTCAACGTATCGTTATTGCTATTGCCCTTGCCTGCCGACCTGATGTCTTGATCTGTGATGAGCCAAC
AACTGCCTTGGATGTAACTATTCAAGCTCAGATTATTGATTTGCTAAAATCTTTACAAAACGAGTATCATTTCACAACAA
TCTTTATTACCCACGACCTTGGTGTGGTGGCAAGTATTGCGGATAAGGTAGCGGTTATGTATGCAGGAGAAATCGTTGAG
TATGGAACGGTTGAGGAAGTCTTCTATGACCCTCGCCATCCATATACATGGAGTCTCTTGTCTAGCTTGCCTCAGCTTGC
TGATGATAAAGGGGATCTTTACTCAATCCCAGGAACACCTCCGTCACTTTATACTGACCTGAAAGGGGATGCTTTTGCCT
TGCGTTCTGACTACGCAATGCAGATTGACTTCGAACAAAAAGCTCCTCAATTCTCAGTATCAGAGACACATTGGGCTAAA
ACTTGGCTTCTTCATGAGGATGCTCCAAAAGTAGAAAAACCAGCTGTGATTGCAAATCTCCATGATAAGATTCGTGAAAA
AATGGGATTTGCCCATCTGGCTGACTAG

Domains

Predicted by InterproScan.

• Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY) (239-301)

• ABC transporter (ABC_tran) (29-187)

3D structure

• AlphaFold DB: A0A062WMA1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
amiE	Streptococcus salivarius strain HSISS4	88.169	100	0.882
amiE	Streptococcus thermophilus LMG 18311	86.479	100	0.865
amiE	Streptococcus thermophilus LMD-9	86.479	100	0.865
oppD	Streptococcus mutans UA159	54.545	99.155	0.541