Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   EQH32_RS01855 Genome accession   NZ_CP035248
Coordinates   360982..361671 (+) Length   229 a.a.
NCBI ID   WP_000518008.1    Uniprot ID   A0A0B7KUQ5
Organism   Streptococcus pneumoniae strain TVO_1901939     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 355982..366671
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH32_RS01830 (EQH32_01935) gpsB 356091..356420 (+) 330 WP_000146522.1 cell division regulator GpsB -
  EQH32_RS01840 (EQH32_01945) - 356906..358063 (+) 1158 WP_000711408.1 class I SAM-dependent RNA methyltransferase -
  EQH32_RS01845 (EQH32_01950) mapZ 358076..359470 (+) 1395 WP_000039278.1 mid-cell-anchored protein MapZ -
  EQH32_RS01850 (EQH32_01955) gndA 359546..360970 (+) 1425 WP_000158793.1 NADP-dependent phosphogluconate dehydrogenase -
  EQH32_RS01855 (EQH32_01960) covR 360982..361671 (+) 690 WP_000518008.1 response regulator transcription factor Regulator
  EQH32_RS01860 (EQH32_01965) cbpC 361769..362725 (+) 957 WP_000771100.1 choline-binding protein CbpC -
  EQH32_RS01865 (EQH32_01970) - 362843..364075 (-) 1233 WP_000765667.1 MFS transporter -
  EQH32_RS01870 (EQH32_01975) - 364118..364705 (-) 588 WP_001818729.1 lanthionine synthetase LanC family protein -
  EQH32_RS01875 (EQH32_01980) - 364605..364941 (-) 337 Protein_371 lanthionine synthetase LanC family protein -
  EQH32_RS10925 - 365603..365770 (+) 168 Protein_372 transposase -
  EQH32_RS10930 - 365810..365932 (+) 123 Protein_373 hypothetical protein -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26914.21 Da        Isoelectric Point: 6.9836

>NTDB_id=337573 EQH32_RS01855 WP_000518008.1 360982..361671(+) (covR) [Streptococcus pneumoniae strain TVO_1901939]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMIL
DHWEDLQEELEVVQRFAVSYIYKPVFIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=337573 EQH32_RS01855 WP_000518008.1 360982..361671(+) (covR) [Streptococcus pneumoniae strain TVO_1901939]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAGAAAGAGCAGTA
TCGGGTTGATCTGGTAGAGGAGGGGCAAAAAGCCCTTTCCATGGCTCTTCAGACAGACTATGATTTGATTTTATTGAACG
TTAATCTGGGAGATATGATGGCTCAGGATTTTGCAGAAAAATTGAGTCGAACTAAACCTGCCTCAGTCATCATGATTTTA
GATCATTGGGAAGACTTGCAAGAAGAGCTGGAAGTTGTTCAGCGTTTTGCAGTTTCATACATCTATAAGCCAGTCTTTAT
CGAAAATCTGGTAGCGCGTATTTCGGCGATCTTCCGAGGTCGGGACTTCATTGATCAACACTGCAGTCTGATGAAAGTTC
CAAGGACCTACCGCAATCTTAGGATAGATGTTGAACATCACACGGTTTATCGTGGTGAAGAGATGATTGCTCTGACCCGC
CGTGAGTATGACCTTTTGGCGACACTTATGGGAAGCAAGAAAGTATTGACTCGTGAGCAATTGTTGGAAAGTGTTTGGAA
GTATGAAAGTGCGACCGAGACAAATATCGTAGATGTCTATATCCGCTATCTACGGAGCAAGCTTGATGTTAAAGGACAAA
AAAGCTACATTAAAACCGTGCGTGGTGTTGGTTACACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0B7KUQ5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.261

100

0.485
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.522

100

0.467

Multiple sequence alignment