Detailed information NTG0337383

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: EQH35_RS09100
• Genome accession: NZ_CP035245
• Coordinates: 1756769..1757806 (-)
• Length: 345 a.a.
• NCBI ID: WP_000727279.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain TVO_1901943
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1751769..1762806

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQH35_RS09075 (EQH35_09585)	-	1752508..1753839 (-)	1332	WP_000390039.1	hemolysin family protein	-
EQH35_RS09080 (EQH35_09590)	endA	1754130..1754954 (-)	825	WP_001036786.1	DNA-entry nuclease EndA	Machinery gene
EQH35_RS09085 (EQH35_09595)	-	1754993..1755181 (-)	189	WP_001036519.1	DNA-directed RNA polymerase subunit beta	-
EQH35_RS09090 (EQH35_09600)	murA	1755174..1756457 (-)	1284	WP_000358034.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
EQH35_RS09095 (EQH35_09605)	-	1756481..1756711 (-)	231	WP_001809307.1	DUF1146 family protein	-
EQH35_RS09100 (EQH35_09610)	sepM	1756769..1757806 (-)	1038	WP_000727279.1	SepM family pheromone-processing serine protease	Regulator
EQH35_RS09105 (EQH35_09615)	coaD	1757790..1758278 (-)	489	WP_001280736.1	pantetheine-phosphate adenylyltransferase	-
EQH35_RS09110 (EQH35_09620)	rsmD	1758268..1758807 (-)	540	WP_000706951.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
EQH35_RS09115 (EQH35_09625)	asnA	1758872..1759864 (-)	993	WP_000747993.1	aspartate--ammonia ligase	-
EQH35_RS09120 (EQH35_09635)	-	1759976..1760659 (-)	684	WP_001016917.1	Bax inhibitor-1/YccA family protein	-
EQH35_RS09125 (EQH35_09640)	-	1760715..1761455 (-)	741	WP_000152680.1	RNA methyltransferase	-
EQH35_RS09130 (EQH35_09645)	-	1761489..1761767 (+)	279	WP_001174613.1	acylphosphatase	-
EQH35_RS09135 (EQH35_09650)	yidC	1761845..1762771 (+)	927	WP_000835949.1	membrane protein insertase YidC	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37565.63 Da
• Isoelectric Point: 5.0724

>NTDB_id=337383 EQH35_RS09100 WP_000727279.1 1756769..1757806(-) (sepM) [Streptococcus pneumoniae strain TVO_1901943]
MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLKVNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFT
DIRSAQETTGGSSDVEFMRINQFYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVISNVPISFSTAGIGGPSAGLMFSL
AIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGIDKKVVASARAGAAIFFAPDNPVSEEEQKAHPDVKNNYQTALEAAK
TIKTDMKIVPVKTLQDAIDYLKNNP

Nucleotide

• Length: 1038 bp

>NTDB_id=337383 EQH35_RS09100 WP_000727279.1 1756769..1757806(-) (sepM) [Streptococcus pneumoniae strain TVO_1901943]
ATGAAAAAAAAGATTAGATGGCCCTTATACGTCATTGCGGCCTTGATTGTGACTTTCTTGGCATTTGTAGTGCCCTTGCC
TTATTATATAGAGGTTCCAGGTGGTTCGGAAGATATTCGCCAAGTCCTTAAAGTAAATGACACAGAAGATAAGGAAGCTG
GTGCCTATCAATTCGTTACGGTTGGTGTTCAACATGCCACTTTAGCTCATATGATTTATGCTTGGTTGACACCTTTTACA
GATATTCGTAGTGCTCAGGAGACTACAGGTGGTTCTTCCGATGTTGAATTTATGCGAATCAATCAATTCTACATGCAAAC
ATCACAAAATATGGCCAAGTATCAAGGACTAAAAACAGCTGGTAAGGATATCGAACTCAAGTACTTTGGAGTTTATGTTT
TGAATGTGACGGATAATTCAACCTTTAAAGGGATTCTCAATATCTCTGATACGGTCACAGCAGTCAATGATCAGACCTTT
GATAGTTCCAAAGACTTGATTGATTACGTCAGTTCTCAAAAATTAGGGGACTCCGTCAAGGTCACCTATGAAGAGGATGG
GCAAACCAAGTCTGCAGAAGGAAAGATTATCACCTTGGAAAATGGAAAAAATGGGATTGGAATCGGCTTGATTGATCGTA
CAGAGGTAATCAGCAATGTCCCAATTAGCTTTTCAACAGCTGGTATTGGCGGCCCAAGTGCTGGTCTCATGTTTAGTCTA
GCTATCTATACTCAAATAGCTCACCCAGATCTTCGTAATGGTCGTATTGTTGCCGGTACAGGTACCATTGACCGCGATGG
TAATGTGGGAGACATTGGAGGTATTGATAAGAAGGTTGTAGCTTCGGCTAGGGCAGGTGCTGCTATTTTCTTTGCTCCTG
ATAACCCTGTTAGCGAAGAAGAACAAAAGGCGCATCCGGACGTGAAAAACAACTACCAAACAGCCCTAGAAGCGGCTAAA
ACAATCAAGACGGATATGAAAATCGTGCCCGTTAAAACCCTACAAGATGCGATTGATTACTTGAAAAACAATCCCTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (130-193)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (231-298)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	59.357	99.13	0.588