Detailed information NTG0337373

Bioinformatically predicted

Overview

• Name: amiE
• Type: Regulator
• Locus tag: EQH35_RS08640
• Genome accession: NZ_CP035245
• Coordinates: 1681220..1682287 (-)
• Length: 355 a.a.
• NCBI ID: WP_000159555.1
• Uniprot ID: A0A0I8P776
• Organism: Streptococcus pneumoniae strain TVO_1901943
• Function: internalize XIP (predicted from homology) Competence regulation

Genomic Context

Location: 1676220..1687287

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQH35_RS08625 (EQH35_09105)	treR	1678008..1678718 (+)	711	WP_000760673.1	trehalose operon repressor	Regulator
EQH35_RS08630 (EQH35_09115)	-	1678873..1680208 (+)	1336	Protein_1732	ISL3 family transposase	-
EQH35_RS08635 (EQH35_09120)	amiF	1680283..1681209 (-)	927	WP_001291293.1	ATP-binding cassette domain-containing protein	Regulator
EQH35_RS08640 (EQH35_09125)	amiE	1681220..1682287 (-)	1068	WP_000159555.1	ABC transporter ATP-binding protein	Regulator
EQH35_RS08645 (EQH35_09130)	amiD	1682296..1683222 (-)	927	WP_000103700.1	oligopeptide ABC transporter permease OppC	Regulator
EQH35_RS08650 (EQH35_09135)	amiC	1683222..1684718 (-)	1497	WP_000759902.1	ABC transporter permease	Regulator
EQH35_RS08655 (EQH35_09140)	amiA3	1684785..1686764 (-)	1980	WP_000742234.1	peptide ABC transporter substrate-binding protein	Regulator

Sequence

Protein

• Length: 355 a.a.
• Molecular weight: 39489.14 Da
• Isoelectric Point: 5.0389

>NTDB_id=337373 EQH35_RS08640 WP_000159555.1 1681220..1682287(-) (amiE) [Streptococcus pneumoniae strain TVO_1901943]
MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALVGESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDL
TALSSHKDWEQIRGAKIATIFQDPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITHDLGVVASIADKVAVMYAGEIVE
YGTVEEVFYDPRHPYTWSLLSSLPQLADDKGDLYSIPGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSKTHWAK
TWLLHEDAPKVEKPAVIANLHDKIREKMGFAHLAD

Nucleotide

• Length: 1068 bp

>NTDB_id=337373 EQH35_RS08640 WP_000159555.1 1681220..1682287(-) (amiE) [Streptococcus pneumoniae strain TVO_1901943]
ATGACAAAAGAAAAAAATGTAATTTTGACTGCTCGCGATATTGTCGTGGAATTTGACGTTCGTGACAAAGTATTGACAGC
CATTCGCGGCGTTTCCCTTGAACTAGTCGAAGGAGAAGTATTAGCCTTGGTAGGTGAGTCAGGATCAGGTAAATCTGTTT
TGACAAAGACCTTCACAGGTATGCTCGAAGAAAATGGTCGTATTGCCCAAGGTAGTATTGACTACCGTGGTCAGGACTTG
ACAGCTTTATCTTCTCACAAGGATTGGGAACAAATTCGTGGTGCTAAGATTGCGACTATCTTCCAGGACCCAATGACTAG
TTTGGACCCCATTAAAACAATTGGTAGTCAGATTACAGAAGTTATTGTAAAACACCAAGGAAAAACAGCTAAAGAAGCGA
AAGAATTGGCCATTGACTACATGAATAAGGTTGGCATTCCAGACGCAGATAGACGTTTTAATGAATACCCATTCCAATAT
TCTGGAGGAATGCGTCAACGTATCGTTATTGCGATTGCCCTTGCCTGCCGACCTGATGTCTTGATCTGTGATGAGCCAAC
AACTGCCTTGGATGTAACTATTCAAGCTCAGATTATTGATTTGCTAAAATCTTTACAAAACGAGTATCATTTCACAACAA
TCTTTATTACCCACGACCTTGGTGTGGTGGCAAGTATTGCGGATAAGGTAGCGGTTATGTATGCAGGAGAAATCGTTGAG
TATGGAACGGTTGAGGAAGTCTTCTATGACCCTCGCCATCCATATACATGGAGTCTCTTGTCTAGCTTGCCTCAGCTTGC
TGATGATAAAGGGGATCTTTACTCAATCCCAGGAACACCTCCGTCACTTTATACTGACCTGAAAGGGGATGCTTTTGCTT
TGCGTTCTGACTACGCAATGCAGATTGACTTCGAACAAAAAGCTCCTCAATTCTCAGTATCAAAGACACATTGGGCTAAA
ACTTGGCTTCTTCATGAGGATGCTCCAAAAGTAGAAAAACCAGCTGTGATTGCAAATCTCCATGATAAGATCCGTGAAAA
AATGGGATTTGCCCATCTGGCTGACTAG

Domains

Predicted by InterproScan.

• Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY) (239-301)

• ABC transporter (ABC_tran) (29-187)

3D structure

• AlphaFold DB: A0A0I8P776

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
amiE	Streptococcus salivarius strain HSISS4	88.169	100	0.882
amiE	Streptococcus thermophilus LMG 18311	86.479	100	0.865
amiE	Streptococcus thermophilus LMD-9	86.479	100	0.865
oppD	Streptococcus mutans UA159	54.545	99.155	0.541