Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   EQH37_RS09260 Genome accession   NZ_CP035243
Coordinates   1849672..1850496 (-) Length   274 a.a.
NCBI ID   WP_001036789.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain TVO_1901946     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 1844672..1855496
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH37_RS09255 (EQH37_09790) - 1848050..1849381 (-) 1332 WP_000390043.1 hemolysin family protein -
  EQH37_RS09260 (EQH37_09795) endA 1849672..1850496 (-) 825 WP_001036789.1 DNA-entry nuclease EndA Machinery gene
  EQH37_RS09265 (EQH37_09800) - 1850535..1850723 (-) 189 WP_001036519.1 DNA-directed RNA polymerase subunit beta -
  EQH37_RS09270 (EQH37_09805) murA 1850716..1851999 (-) 1284 WP_000358028.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  EQH37_RS09275 (EQH37_09810) - 1852023..1852253 (-) 231 WP_000250383.1 DUF1146 family protein -
  EQH37_RS09280 (EQH37_09815) sepM 1852311..1853348 (-) 1038 WP_000727277.1 SepM family pheromone-processing serine protease Regulator
  EQH37_RS09285 (EQH37_09820) coaD 1853332..1853820 (-) 489 WP_001280723.1 pantetheine-phosphate adenylyltransferase -
  EQH37_RS09290 (EQH37_09825) rsmD 1853810..1854349 (-) 540 WP_000706960.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  EQH37_RS09295 (EQH37_09830) asnA 1854414..1855406 (-) 993 WP_000747993.1 aspartate--ammonia ligase -

Sequence

Protein


Download         Length: 274 a.a.        Molecular weight: 29966.67 Da        Isoelectric Point: 10.1700

>NTDB_id=337231 EQH37_RS09260 WP_001036789.1 1849672..1850496(-) (endA) [Streptococcus pneumoniae strain TVO_1901946]
MNKKTRQTLIGLLVLLLLSTGSYYIKQMQSTANSPKTKLNQKKQASEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIV
NGNKTNLDAKVSSKPYADNKTKTVGKETVPTVANALLSKATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRVRYRVTLYYASNEDLVPSASQIE
AKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ

Nucleotide


Download         Length: 825 bp        

>NTDB_id=337231 EQH37_RS09260 WP_001036789.1 1849672..1850496(-) (endA) [Streptococcus pneumoniae strain TVO_1901946]
ATGAACAAAAAAACAAGACAGACACTAATCGGACTGCTAGTGTTATTGCTTTTGTCTACAGGGAGCTATTATATCAAGCA
GATGCAGTCGACAGCTAATAGTCCTAAAACCAAGCTTAATCAGAAAAAACAAGCGTCTGAAGCTCCTAGTCAAGCATTGG
CAGAGAGTGTCTTAACAGACGCAGTCAAGAGTCAAATAAAGGGGAGTCTGGAGTGGAATGGCTCAGGTGCTTTTATCGTC
AATGGTAATAAAACAAATCTAGATGCCAAGGTTTCAAGTAAGCCCTACGCTGACAATAAAACAAAGACAGTGGGCAAGGA
AACTGTTCCAACCGTAGCTAATGCCCTCTTGTCTAAGGCCACTCGTCAGTACAAGAATCGTAAAGAAACTGGGAATGGTT
CAACTTCTTGGACTCCTCCAGGTTGGCATCAGGTCAAGAATCTAAAGGGCTCTTATACCCATGCAGTCGATAGAGGTCAT
TTGTTAGGCTATGCCTTAATCGGTGGTTTGGATGGTTTTGATGCCTCAACAAGCAATCCTAAAAACATTGCTGTTCAGAC
AGCCTGGGCAAATCAGGCACAAGCCGAGTATTCGACTGGTCAAAACTACTATGAAAGCAAGGTGCGTAAAGCCTTGGACC
AAAACAAGCGTGTCCGTTACCGTGTAACCCTTTACTACGCTTCAAACGAGGATTTAGTTCCCTCAGCTTCACAGATTGAA
GCCAAGTCTTCGGATGGAGAATTGGAATTCAATGTTCTAGTTCCCAATGTTCAAAAGGGACTTCAACTGGATTACCGAAC
TGGAGAAGTAACTGTAACTCAGTAA

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(75-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

98.175

100

0.982
  endA Streptococcus pneumoniae D39

98.175

100

0.982
  endA Streptococcus pneumoniae R6

98.175

100

0.982
  endA Streptococcus pneumoniae TIGR4

98.175

100

0.982

Multiple sequence alignment