Detailed information NTG0337083

Bioinformatically predicted

Overview

• Name: comGF/cglF
• Type: Machinery gene
• Locus tag: EQH39_RS09160
• Genome accession: NZ_CP035241
• Coordinates: 1795168..1795629 (-)
• Length: 153 a.a.
• NCBI ID: WP_000250542.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain TVO_1901948
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1790168..1800629

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQH39_RS09130 (EQH39_09605)	-	1790472..1791296 (-)	825	WP_000727904.1	membrane protein insertase YidC	-
EQH39_RS09135 (EQH39_09610)	rnpA	1791271..1791642 (-)	372	WP_000739246.1	ribonuclease P protein component	-
EQH39_RS10255	-	1791659..1791790 (-)	132	WP_000768904.1	hypothetical protein	-
EQH39_RS09140 (EQH39_09615)	-	1791791..1792981 (-)	1191	WP_000167767.1	acetate kinase	-
EQH39_RS09145 (EQH39_09620)	comYH	1793032..1793985 (-)	954	WP_000345101.1	class I SAM-dependent methyltransferase	Machinery gene
EQH39_RS09150 (EQH39_09625)	-	1794046..1794640 (-)	595	Protein_1793	class I SAM-dependent methyltransferase	-
EQH39_RS09155 (EQH39_09630)	comGG/cglG	1794777..1795190 (-)	414	WP_000265624.1	competence type IV pilus minor pilin ComGG	Machinery gene
EQH39_RS09160 (EQH39_09635)	comGF/cglF	1795168..1795629 (-)	462	WP_000250542.1	competence type IV pilus minor pilin ComGF	Machinery gene
EQH39_RS09165 (EQH39_09640)	comGE/cglE	1795592..1795894 (-)	303	WP_000413382.1	competence type IV pilus minor pilin ComGE	Machinery gene
EQH39_RS09170 (EQH39_09645)	comGD/cglD	1795857..1796261 (-)	405	WP_000588013.1	competence type IV pilus minor pilin ComGD	Machinery gene
EQH39_RS09175 (EQH39_09650)	comGC/cglC	1796254..1796580 (-)	327	WP_000738636.1	comG operon protein ComGC	Machinery gene
EQH39_RS09180 (EQH39_09655)	comGB/cglB	1796582..1797598 (-)	1017	WP_074017570.1	competence type IV pilus assembly protein ComGB	Machinery gene
EQH39_RS09185 (EQH39_09660)	comGA/cglA/cilD	1797546..1798487 (-)	942	WP_000249552.1	competence type IV pilus ATPase ComGA	Machinery gene
EQH39_RS09190 (EQH39_09665)	-	1798563..1798928 (-)	366	WP_000286415.1	DUF1033 family protein	-
EQH39_RS09195 (EQH39_09670)	-	1799079..1800137 (-)	1059	WP_000649468.1	zinc-dependent alcohol dehydrogenase family protein	-

Sequence

Protein

• Length: 153 a.a.
• Molecular weight: 17918.53 Da
• Isoelectric Point: 9.3137

>NTDB_id=337083 EQH39_RS09160 WP_000250542.1 1795168..1795629(-) (comGF/cglF) [Streptococcus pneumoniae strain TVO_1901948]
MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQTMSQLLISEVRYQQQSEQKEWLLFVDQLEAELDRSQFEKVEGN
RLYMKQDGKDIAIGKSKSDDFRKTNARGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEKS

Nucleotide

• Length: 462 bp

>NTDB_id=337083 EQH39_RS09160 WP_000250542.1 1795168..1795629(-) (comGF/cglF) [Streptococcus pneumoniae strain TVO_1901948]
ATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAAGGTCAAGGCTTTTACCTTGTTAGAATCCCTACTTGCCCTCAT
TGTCATCAGTGGGGGATTACTCCTTTTTCAAACTATGAGTCAGCTCCTCATTTCAGAAGTTCGCTACCAGCAACAAAGCG
AGCAAAAGGAGTGGCTCTTGTTTGTGGACCAACTTGAGGCAGAATTAGACCGTTCGCAGTTCGAAAAAGTAGAAGGCAAT
CGCCTATACATGAAGCAAGATGGCAAGGACATCGCCATCGGTAAGTCAAAGTCAGACGATTTTCGTAAAACGAATGCTCG
TGGTCGAGGTTATCAGCCTATGGTTTATGGCCTCAAATCAGCTCAGATTACAGAGGACAATCAACTGGTTCATTTTCGTT
TCCAGTTTCAAAAAGGCTTAGAAAGGGAGTTCATCTATCGTGTGGAAAAAGAAAAAAGTTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (45-141)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF/cglF	Streptococcus pneumoniae Rx1	96.078	100	0.961
comGF/cglF	Streptococcus pneumoniae D39	96.078	100	0.961
comGF/cglF	Streptococcus pneumoniae R6	96.078	100	0.961
comGF/cglF	Streptococcus pneumoniae TIGR4	96.078	100	0.961
comGF/cglF	Streptococcus mitis SK321	92.157	100	0.922
comGF/cglF	Streptococcus mitis NCTC 12261	90.85	100	0.909