Detailed information NTG0336830

Bioinformatically predicted

Overview

• Name: treR
• Type: Regulator
• Locus tag: EQH43_RS08615
• Genome accession: NZ_CP035237
• Coordinates: 1712005..1712715 (+)
• Length: 236 a.a.
• NCBI ID: WP_000760673.1
• Uniprot ID: A0A062WVH4
• Organism: Streptococcus pneumoniae strain TVO_Taiwan19F-14
• Function: regulate expression of competence genes (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IScluster/Tn	1712872..1715906	1712005..1712715	flank	157

Gene organization within MGE regions

Location: 1712005..1715906

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQH43_RS08615 (EQH43_09055)	treR	1712005..1712715 (+)	711	WP_000760673.1	trehalose operon repressor	Regulator
EQH43_RS08620 (EQH43_09060)	-	1712872..1714015 (+)	1144	Protein_1725	transposase	-
EQH43_RS08625 (EQH43_09070)	-	1714182..1715528 (+)	1347	WP_041179004.1	IS1380-like element ISSpn5 family transposase	-
EQH43_RS08630 (EQH43_09075)	-	1715721..1715906 (+)	186	Protein_1727	transposase	-

Sequence

Protein

• Length: 236 a.a.
• Molecular weight: 27607.78 Da
• Isoelectric Point: 8.9698

>NTDB_id=336830 EQH43_RS08615 WP_000760673.1 1712005..1712715(+) (treR) [Streptococcus pneumoniae strain TVO_Taiwan19F-14]
MKKYQQLFKQIQETIQNETYAVGDFLPSEHDLMEQYQVSRDTVRKALSLLQEEGLIKKIRGQGSQVVKEETVNFPVSNLT
SYQELVKELGLRSKTNVVSLDKIIIDKKSSLITGFPEFRMVWKVVRQRVVDDLVSVLDTDYLDMELIPNLTRQIAEQSIY
SYIENGLKLLIDYAQKEITIDHSSDRDKILMDIGKDPYVVSIKSKVYLQDGRQFQFTESRHKLEKFRFVDFAKRKK

Nucleotide

• Length: 711 bp

>NTDB_id=336830 EQH43_RS08615 WP_000760673.1 1712005..1712715(+) (treR) [Streptococcus pneumoniae strain TVO_Taiwan19F-14]
ATGAAGAAATACCAACAATTATTTAAGCAAATCCAAGAAACCATTCAAAACGAGACTTACGCTGTCGGAGATTTCCTTCC
TAGCGAGCACGACCTTATGGAGCAATATCAAGTGAGTCGTGATACCGTCCGAAAGGCCCTGTCTCTCCTCCAAGAGGAAG
GATTGATCAAAAAGATAAGAGGGCAAGGTTCTCAAGTCGTCAAAGAAGAAACCGTCAATTTCCCTGTATCCAACCTAACC
AGCTACCAAGAACTAGTTAAAGAACTTGGACTGCGCTCTAAAACCAACGTGGTCAGTCTGGACAAGATTATTATTGATAA
AAAATCCTCACTGATAACCGGTTTCCCAGAGTTTCGGATGGTTTGGAAGGTGGTCCGCCAGCGTGTGGTGGATGATCTGG
TATCCGTTCTGGATACAGACTATCTGGATATGGAACTCATCCCAAATCTCACTCGCCAAATTGCTGAGCAGTCTATCTAT
TCTTATATAGAAAATGGCCTCAAACTCCTTATTGATTATGCTCAGAAGGAAATCACCATTGACCACTCAAGCGACCGAGA
CAAGATTCTCATGGACATTGGCAAAGACCCTTATGTCGTTTCGATTAAATCAAAAGTCTATCTCCAAGACGGACGCCAAT
TTCAGTTTACCGAAAGTCGCCATAAGTTAGAGAAATTTAGATTTGTAGATTTTGCAAAACGCAAGAAATAA

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, gntR family (GntR) (3-66)

• UTRA domain (UTRA) (89-227)

3D structure

• AlphaFold DB: A0A062WVH4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
treR	Streptococcus mutans UA159	59.322	100	0.593