Detailed information NTG0336714

Bioinformatically predicted

Overview

• Name: comFA
• Type: Machinery gene
• Locus tag: FZC50_RS04120
• Genome accession: NZ_CP043392
• Coordinates: 834020..835102 (+)
• Length: 360 a.a.
• NCBI ID: WP_001548033.1
• Uniprot ID: A0A0H2XJ41
• Organism: Staphylococcus aureus strain NRS384-rpoB-H481N-NCV
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 829020..840102

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FZC50_RS04100 (FZC50_04100)	-	829392..830462 (-)	1071	WP_000460983.1	GGDEF domain-containing protein GdpS	-
FZC50_RS04105 (FZC50_04105)	-	830780..831835 (+)	1056	WP_000258151.1	glycosyltransferase family 4 protein	-
FZC50_RS04110 (FZC50_04110)	-	832005..832646 (-)	642	WP_000192947.1	YigZ family protein	-
FZC50_RS04115 (FZC50_04115)	fakB1	832790..833656 (+)	867	WP_000686342.1	fatty acid kinase binding subunit FakB1	-
FZC50_RS04120 (FZC50_04120)	comFA	834020..835102 (+)	1083	WP_001548033.1	DEAD/DEAH box helicase	Machinery gene
FZC50_RS04125 (FZC50_04125)	-	835095..835769 (+)	675	WP_001057965.1	ComF family protein	-
FZC50_RS04130 (FZC50_04130)	hpf	835830..836402 (+)	573	WP_000617735.1	ribosome hibernation-promoting factor, HPF/YfiA family	-
FZC50_RS04135 (FZC50_04135)	secA	836816..839347 (+)	2532	WP_000506531.1	preprotein translocase subunit SecA	-
FZC50_RS04140 (FZC50_04140)	-	839389..839493 (+)	105	WP_001790092.1	hypothetical protein	-

Sequence

Protein

• Length: 360 a.a.
• Molecular weight: 42111.65 Da
• Isoelectric Point: 9.8307

>NTDB_id=336714 FZC50_RS04120 WP_001548033.1 834020..835102(+) (comFA) [Staphylococcus aureus strain NRS384-rpoB-H481N-NCV]
MDNVTRYKITESSQSSSQAYYHLSFELSEQQSYASEHIVRAIRKRQTILLYAVTGAGKTEMMFQGIQYARIQGDNIAIVS
PRVDVVVEISKRIKDAFLNEDIDILHQQSRQQFEGHFVVCTVHQLYRFKQHFDTIFIDEVDAFPLSMDKNLQQALKSSSK
VEHATIYMTATPPKQLLSEIPHENIIKLPARFHKKSLPVPKYRYFKLNNKKIQKMLYRILQDQINNQRYTLVFFNNIETM
IKTFSVYKQKITKLTYVHSEDVFRFEKVEQLRNGHFDVIFTTTILERGFTMANLDVVVIDAHQYTQEALIQIAGRVGRKL
ECPTGKVLFFHEGVSMNMIQAKKEIQRMNKLALKRGWIDE

Nucleotide

• Length: 1083 bp

>NTDB_id=336714 FZC50_RS04120 WP_001548033.1 834020..835102(+) (comFA) [Staphylococcus aureus strain NRS384-rpoB-H481N-NCV]
ATGGATAATGTAACAAGATATAAAATAACAGAGAGTTCGCAAAGTTCATCACAAGCATATTATCATCTCTCATTTGAATT
GTCGGAACAGCAGTCTTATGCCTCAGAACATATTGTTCGAGCCATTAGAAAGAGACAAACGATTTTGTTATATGCCGTAA
CAGGTGCAGGTAAGACAGAAATGATGTTTCAAGGCATTCAATATGCAAGAATACAGGGAGATAATATAGCTATTGTGTCA
CCACGTGTAGATGTTGTTGTAGAAATTAGTAAACGTATTAAAGACGCATTTCTTAATGAAGATATAGACATACTACACCA
GCAATCAAGACAACAATTTGAAGGGCATTTTGTTGTATGCACAGTGCATCAACTTTACCGATTCAAACAGCACTTTGATA
CTATTTTTATTGATGAAGTCGATGCCTTTCCTTTATCAATGGATAAAAATTTACAACAAGCATTGAAGTCATCTTCTAAA
GTTGAACATGCAACAATTTATATGACAGCAACACCACCGAAACAACTTCTGTCAGAGATTCCCCACGAAAATATAATTAA
ATTGCCAGCTCGCTTTCATAAAAAATCACTTCCAGTTCCTAAATATCGTTATTTCAAACTTAATAATAAGAAGATTCAGA
AAATGTTATACCGAATTTTACAAGATCAAATTAATAATCAACGTTATACACTGGTGTTTTTTAACAATATAGAAACAATG
ATTAAAACATTTTCGGTTTATAAGCAGAAAATTACTAAATTAACATACGTCCATAGCGAGGATGTTTTTCGCTTTGAAAA
AGTTGAACAATTAAGGAATGGACATTTCGATGTCATTTTTACTACGACAATATTAGAACGTGGATTTACAATGGCAAATT
TGGATGTTGTTGTTATCGATGCACATCAATATACTCAAGAGGCTTTAATACAAATTGCTGGACGTGTTGGACGAAAATTA
GAATGTCCTACTGGAAAAGTATTGTTTTTTCATGAAGGGGTAAGTATGAATATGATTCAAGCTAAAAAAGAGATTCAAAG
GATGAACAAATTAGCATTAAAAAGAGGTTGGATTGATGAATAA

Domains

Predicted by InterProScan.

• Helicase conserved C-terminal domain (Helicase_C) (215-318)

• Type III restriction enzyme, res subunit (ResIII) (25-173)

3D structure

• AlphaFold DB: A0A0H2XJ41

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comFA	Bacillus subtilis subsp. subtilis str. 168	38.938	94.167	0.367