Detailed information NTG0336682

Bioinformatically predicted

Overview

• Name: amiE
• Type: Regulator
• Locus tag: EQH45_RS08955
• Genome accession: NZ_CP035235
• Coordinates: 1771270..1772337 (-)
• Length: 355 a.a.
• NCBI ID: WP_000159554.1
• Uniprot ID: A0A062WMA1
• Organism: Streptococcus pneumoniae strain TVO_1902276
• Function: internalize XIP (predicted from homology) Competence regulation

Genomic Context

Location: 1766270..1777337

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQH45_RS08930 (EQH45_09405)	treR	1766442..1767152 (+)	711	WP_000760673.1	trehalose operon repressor	Regulator
EQH45_RS08935 (EQH45_09410)	-	1767185..1767988 (-)	804	WP_000202630.1	ABC transporter ATP-binding protein	-
EQH45_RS08940 (EQH45_09415)	-	1768001..1768894 (-)	894	WP_001012092.1	ABC transporter permease	-
EQH45_RS08945 (EQH45_09420)	-	1768906..1769715 (-)	810	WP_001850051.1	ABC transporter substrate-binding protein	-
EQH45_RS08950 (EQH45_09425)	amiF	1770333..1771259 (-)	927	WP_001291293.1	ATP-binding cassette domain-containing protein	Regulator
EQH45_RS08955 (EQH45_09430)	amiE	1771270..1772337 (-)	1068	WP_000159554.1	ABC transporter ATP-binding protein	Regulator
EQH45_RS08960 (EQH45_09435)	amiD	1772346..1773272 (-)	927	WP_000103700.1	oligopeptide ABC transporter permease OppC	Regulator
EQH45_RS08965 (EQH45_09440)	amiC	1773272..1774768 (-)	1497	WP_000759903.1	ABC transporter permease	Regulator
EQH45_RS08970 (EQH45_09445)	amiA3	1774835..1776814 (-)	1980	WP_000742232.1	peptide ABC transporter substrate-binding protein	Regulator

Sequence

Protein

• Length: 355 a.a.
• Molecular weight: 39490.09 Da
• Isoelectric Point: 4.8727

>NTDB_id=336682 EQH45_RS08955 WP_000159554.1 1771270..1772337(-) (amiE) [Streptococcus pneumoniae strain TVO_1902276]
MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALVGESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDL
TALSSHKDWEQIRGAKIATIFQDPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITHDLGVVASIADKVAVMYAGEIVE
YGTVEEVFYDPRHPYTWSLLSSLPQLADDKGDLYSIPGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAK
TWLLHEDAPKVEKPAVIANLHDKIREKMGFAHLAD

Nucleotide

• Length: 1068 bp

>NTDB_id=336682 EQH45_RS08955 WP_000159554.1 1771270..1772337(-) (amiE) [Streptococcus pneumoniae strain TVO_1902276]
ATGACAAAAGAAAAAAATGTAATTTTGACTGCTCGCGATATTGTCGTGGAATTTGACGTTCGTGACAAAGTATTGACAGC
CATTCGCGGCGTTTCCCTTGAACTAGTCGAAGGAGAAGTATTAGCCTTGGTAGGTGAGTCAGGATCAGGTAAATCTGTTT
TGACAAAGACCTTCACAGGTATGCTCGAAGAAAATGGTCGCATTGCCCAAGGTAGTATTGACTACCGTGGTCAGGACTTG
ACAGCTTTATCTTCTCACAAGGATTGGGAACAAATTCGTGGTGCTAAGATTGCGACTATCTTCCAGGACCCAATGACTAG
TTTGGACCCCATTAAAACAATTGGTAGTCAGATTACAGAAGTTATTGTAAAACACCAAGGAAAAACAGCTAAAGAAGCGA
AAGAATTGGCCATTGACTACATGAATAAGGTTGGCATTCCAGACGCAGATAGACGTTTTAATGAATACCCATTCCAATAT
TCTGGAGGAATGCGTCAACGTATCGTTATTGCGATTGCCCTTGCCTGCCGACCTGATGTCTTGATCTGTGATGAGCCAAC
AACTGCCTTGGATGTAACTATTCAAGCTCAGATTATTGATTTGCTAAAATCTTTACAAAACGAGTATCATTTCACAACAA
TCTTTATTACCCACGACCTTGGTGTGGTGGCAAGTATTGCGGATAAGGTAGCGGTTATGTATGCAGGAGAAATCGTTGAG
TATGGAACGGTTGAGGAAGTCTTCTATGACCCTCGCCATCCATATACATGGAGTCTCTTGTCTAGCTTGCCTCAGCTTGC
TGATGATAAAGGGGATCTTTACTCAATCCCAGGAACACCTCCGTCACTTTATACTGACCTGAAAGGGGATGCTTTTGCCT
TGCGTTCTGACTACGCAATGCAGATTGACTTCGAACAAAAAGCTCCTCAATTCTCAGTATCAGAGACACATTGGGCTAAA
ACTTGGCTTCTTCATGAGGATGCTCCAAAAGTAGAAAAACCAGCTGTGATTGCAAATCTCCATGATAAGATCCGTGAAAA
AATGGGATTTGCCCATCTGGCTGACTAG

Domains

Predicted by InterproScan.

• Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY) (239-301)

• ABC transporter (ABC_tran) (29-187)

3D structure

• AlphaFold DB: A0A062WMA1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
amiE	Streptococcus salivarius strain HSISS4	88.169	100	0.882
amiE	Streptococcus thermophilus LMG 18311	86.479	100	0.865
amiE	Streptococcus thermophilus LMD-9	86.479	100	0.865
oppD	Streptococcus mutans UA159	54.545	99.155	0.541