Detailed information NTG0336606

Bioinformatically predicted

Overview

• Name: amiE
• Type: Regulator
• Locus tag: EQH46_RS08755
• Genome accession: NZ_CP035234
• Coordinates: 1733118..1734185 (-)
• Length: 355 a.a.
• NCBI ID: WP_000159554.1
• Uniprot ID: A0A062WMA1
• Organism: Streptococcus pneumoniae strain TVO_1902277
• Function: internalize XIP (predicted from homology) Competence regulation

Genomic Context

Location: 1728118..1739185

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQH46_RS08730 (EQH46_09185)	treR	1728290..1729000 (+)	711	WP_000760673.1	trehalose operon repressor	Regulator
EQH46_RS08735 (EQH46_09190)	-	1729033..1729836 (-)	804	WP_000202630.1	ABC transporter ATP-binding protein	-
EQH46_RS08740 (EQH46_09195)	-	1729849..1730742 (-)	894	WP_001012092.1	ABC transporter permease	-
EQH46_RS08745 (EQH46_09200)	-	1730754..1731563 (-)	810	WP_001850051.1	ABC transporter substrate-binding protein	-
EQH46_RS08750 (EQH46_09205)	amiF	1732181..1733107 (-)	927	WP_001291293.1	ATP-binding cassette domain-containing protein	Regulator
EQH46_RS08755 (EQH46_09210)	amiE	1733118..1734185 (-)	1068	WP_000159554.1	ABC transporter ATP-binding protein	Regulator
EQH46_RS08760 (EQH46_09215)	amiD	1734194..1735120 (-)	927	WP_000103700.1	oligopeptide ABC transporter permease OppC	Regulator
EQH46_RS08765 (EQH46_09220)	amiC	1735120..1736616 (-)	1497	WP_000759903.1	ABC transporter permease	Regulator
EQH46_RS08770 (EQH46_09225)	-	1736683..1738662 (-)	1980	Protein_1765	peptide ABC transporter substrate-binding protein	-

Sequence

Protein

• Length: 355 a.a.
• Molecular weight: 39490.09 Da
• Isoelectric Point: 4.8727

>NTDB_id=336606 EQH46_RS08755 WP_000159554.1 1733118..1734185(-) (amiE) [Streptococcus pneumoniae strain TVO_1902277]
MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALVGESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDL
TALSSHKDWEQIRGAKIATIFQDPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITHDLGVVASIADKVAVMYAGEIVE
YGTVEEVFYDPRHPYTWSLLSSLPQLADDKGDLYSIPGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAK
TWLLHEDAPKVEKPAVIANLHDKIREKMGFAHLAD

Nucleotide

• Length: 1068 bp

>NTDB_id=336606 EQH46_RS08755 WP_000159554.1 1733118..1734185(-) (amiE) [Streptococcus pneumoniae strain TVO_1902277]
ATGACAAAAGAAAAAAATGTAATTTTGACTGCTCGCGATATTGTCGTGGAATTTGACGTTCGTGACAAAGTATTGACAGC
CATTCGCGGCGTTTCCCTTGAACTAGTCGAAGGAGAAGTATTAGCCTTGGTAGGTGAGTCAGGATCAGGTAAATCTGTTT
TGACAAAGACCTTCACAGGTATGCTCGAAGAAAATGGTCGCATTGCCCAAGGTAGTATTGACTACCGTGGTCAGGACTTG
ACAGCTTTATCTTCTCACAAGGATTGGGAACAAATTCGTGGTGCTAAGATTGCGACTATCTTCCAGGACCCAATGACTAG
TTTGGACCCCATTAAAACAATTGGTAGTCAGATTACAGAAGTTATTGTAAAACACCAAGGAAAAACAGCTAAAGAAGCGA
AAGAATTGGCCATTGACTACATGAATAAGGTTGGCATTCCAGACGCAGATAGACGTTTTAATGAATACCCATTCCAATAT
TCTGGAGGAATGCGTCAACGTATCGTTATTGCGATTGCCCTTGCCTGCCGACCTGATGTCTTGATCTGTGATGAGCCAAC
AACTGCCTTGGATGTAACTATTCAAGCTCAGATTATTGATTTGCTAAAATCTTTACAAAACGAGTATCATTTCACAACAA
TCTTTATTACCCACGACCTTGGTGTGGTGGCAAGTATTGCGGATAAGGTAGCGGTTATGTATGCAGGAGAAATCGTTGAG
TATGGAACGGTTGAGGAAGTCTTCTATGACCCTCGCCATCCATATACATGGAGTCTCTTGTCTAGCTTGCCTCAGCTTGC
TGATGATAAAGGGGATCTTTACTCAATCCCAGGAACACCTCCGTCACTTTATACTGACCTGAAAGGGGATGCTTTTGCCT
TGCGTTCTGACTACGCAATGCAGATTGACTTCGAACAAAAAGCTCCTCAATTCTCAGTATCAGAGACACATTGGGCTAAA
ACTTGGCTTCTTCATGAGGATGCTCCAAAAGTAGAAAAACCAGCTGTGATTGCAAATCTCCATGATAAGATCCGTGAAAA
AATGGGATTTGCCCATCTGGCTGACTAG

Domains

Predicted by InterproScan.

• Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY) (239-301)

• ABC transporter (ABC_tran) (29-187)

3D structure

• AlphaFold DB: A0A062WMA1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
amiE	Streptococcus salivarius strain HSISS4	88.169	100	0.882
amiE	Streptococcus thermophilus LMG 18311	86.479	100	0.865
amiE	Streptococcus thermophilus LMD-9	86.479	100	0.865
oppD	Streptococcus mutans UA159	54.545	99.155	0.541