Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD/comD1   Type   Regulator
Locus tag   SGGBAA2069_RS10060 Genome accession   NC_015215
Coordinates   2020017..2021327 (-) Length   436 a.a.
NCBI ID   WP_013643487.1    Uniprot ID   -
Organism   Streptococcus gallolyticus subsp. gallolyticus ATCC BAA-2069     
Function   phosphorylation of ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 2015017..2026327
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SGGBAA2069_RS10020 (SGGBAA2069_c19610) - 2015402..2015602 (-) 201 WP_013643478.1 hypothetical protein -
  SGGBAA2069_RS10025 (SGGBAA2069_c19620) comD/comD3 2015734..2017098 (-) 1365 WP_039695025.1 GHKL domain-containing protein Regulator
  SGGBAA2069_RS10030 (SGGBAA2069_c19630) comE/comE2 2017111..2017839 (-) 729 WP_043913786.1 LytR/AlgR family response regulator transcription factor Regulator
  SGGBAA2069_RS10035 (SGGBAA2069_c19640) - 2017937..2018230 (-) 294 WP_009854994.1 bacteriocin immunity protein -
  SGGBAA2069_RS10040 (SGGBAA2069_c19650) - 2018281..2018508 (-) 228 WP_013643481.1 hypothetical protein -
  SGGBAA2069_RS10045 (SGGBAA2069_c19670) - 2018777..2019088 (-) 312 WP_003066564.1 bacteriocin immunity protein -
  SGGBAA2069_RS10050 (SGGBAA2069_c19680) - 2019100..2019249 (-) 150 WP_013643483.1 hypothetical protein -
  SGGBAA2069_RS10055 (SGGBAA2069_c19690) - 2019306..2019557 (-) 252 WP_231844599.1 DUF3884 family protein -
  SGGBAA2069_RS12190 (SGGBAA2069_c19710) - 2019858..2020028 (+) 171 WP_013643486.1 hypothetical protein -
  SGGBAA2069_RS10060 (SGGBAA2069_c19720) comD/comD1 2020017..2021327 (-) 1311 WP_013643487.1 sensor histidine kinase Regulator
  SGGBAA2069_RS10065 (SGGBAA2069_c19730) comE/comE1 2021332..2022063 (-) 732 WP_013643488.1 response regulator transcription factor Regulator
  SGGBAA2069_RS10070 - 2022080..2022406 (-) 327 WP_009855002.1 LytTR family DNA-binding domain-containing protein -
  SGGBAA2069_RS10075 (SGGBAA2069_c19740) - 2022590..2023882 (-) 1293 WP_013643489.1 glycosyltransferase family 2 protein -
  SGGBAA2069_RS10080 (SGGBAA2069_c19750) - 2023884..2024183 (-) 300 WP_013643490.1 DUF3884 family protein -
  SGGBAA2069_RS10085 (SGGBAA2069_c19760) - 2024209..2024391 (-) 183 WP_013643491.1 hypothetical protein -
  SGGBAA2069_RS10090 (SGGBAA2069_c19770) - 2024473..2024682 (-) 210 WP_013643492.1 helix-turn-helix domain-containing protein -
  SGGBAA2069_RS10095 (SGGBAA2069_c19780) - 2024672..2025685 (-) 1014 WP_013643493.1 thiol reductase thioredoxin -
  SGGBAA2069_RS10100 (SGGBAA2069_c19790) - 2026062..2026259 (-) 198 WP_009855009.1 class IIb bacteriocin, lactobin A/cerein 7B family -

Sequence

Protein


Download         Length: 436 a.a.        Molecular weight: 50880.76 Da        Isoelectric Point: 5.6978

>NTDB_id=33651 SGGBAA2069_RS10060 WP_013643487.1 2020017..2021327(-) (comD/comD1) [Streptococcus gallolyticus subsp. gallolyticus ATCC BAA-2069]
MLDYLFLCLIVNSFILYIYSQVRGEKLNFFEILIAVAVFVWVDHAWFYFIICNFIILILLSYLKNRSLPLTLHVFYGVFP
WIVESVFRRLIGFFMLPIIGLNYLNVGENNIIFMCVELTSLMLYILLVKISKFDFQRFIEMVSVSILRFFLIVTDVTMIA
FYVAIEFLTGMEVYGGVPNLVYRQWLVALYFTFFILMLFYMNRSYQNWLEKEVSLAREQELHSLSVYSKQIEGLYEELRA
FRHDYANILVSLKEGIDQNDMDMVRNIYNSVLEESGHLVQNKKFDIGRLINIDNDAIKSVLSAKSLEAESYHIAVQLEVK
DKIGLPEIPLLDYVRLLSILCDNAIEAAMEAENPAMIIACFYQGDDYLLVIDNTTKEERVPVELIYQKNYSSKGFGRGVG
LKTVNQMLKKYPNMSVQTSSKNYHFRQTICIKKSFD

Nucleotide


Download         Length: 1311 bp        

>NTDB_id=33651 SGGBAA2069_RS10060 WP_013643487.1 2020017..2021327(-) (comD/comD1) [Streptococcus gallolyticus subsp. gallolyticus ATCC BAA-2069]
ATGTTGGATTACTTATTTCTTTGCTTAATAGTAAATTCGTTTATTCTATACATTTATTCTCAAGTCAGAGGTGAGAAGTT
AAACTTTTTTGAGATATTAATAGCAGTTGCTGTTTTTGTATGGGTTGATCATGCTTGGTTTTATTTTATTATATGTAATT
TTATTATTCTGATATTGTTATCTTATCTAAAAAATAGGTCTTTACCACTAACACTTCATGTCTTTTATGGTGTTTTTCCT
TGGATTGTTGAGAGTGTTTTTAGGCGTTTGATAGGTTTCTTTATGCTTCCAATCATTGGTTTAAATTATCTGAATGTAGG
TGAAAATAATATAATTTTTATGTGTGTCGAGCTAACATCCCTAATGCTTTATATTTTGCTAGTGAAAATTTCTAAATTTG
ATTTTCAAAGATTTATAGAAATGGTTAGTGTCAGCATATTAAGATTTTTTCTTATTGTTACTGATGTAACGATGATTGCT
TTTTATGTGGCTATTGAATTTCTAACAGGTATGGAAGTTTATGGTGGTGTCCCAAACTTGGTTTATCGCCAATGGTTGGT
GGCTCTCTATTTCACTTTCTTCATTTTAATGCTGTTTTATATGAATCGCTCTTATCAAAATTGGCTTGAGAAAGAAGTGT
CGTTAGCGCGGGAGCAAGAACTGCATTCTTTGTCGGTATATAGCAAGCAAATCGAAGGCTTATATGAAGAACTAAGAGCT
TTTCGTCATGATTATGCCAATATCTTAGTGAGTTTAAAAGAAGGAATCGACCAAAATGATATGGATATGGTCAGAAATAT
TTACAATTCTGTATTGGAAGAGTCAGGGCACCTTGTTCAGAATAAAAAATTTGATATTGGACGATTGATTAATATTGACA
ATGATGCAATAAAAAGTGTATTATCAGCAAAGTCTTTAGAGGCTGAGTCTTATCATATTGCCGTTCAATTAGAGGTTAAG
GATAAGATCGGACTTCCTGAGATACCATTACTAGACTATGTGCGACTTTTGTCGATTTTGTGTGATAATGCGATTGAAGC
AGCTATGGAAGCTGAAAATCCTGCCATGATTATTGCTTGTTTCTATCAAGGGGATGACTATTTACTAGTTATCGATAACA
CCACAAAAGAAGAACGAGTTCCTGTGGAATTGATTTATCAGAAGAATTATTCAAGTAAGGGCTTTGGACGAGGTGTTGGT
CTTAAAACGGTTAACCAGATGTTGAAAAAGTATCCAAATATGTCGGTACAAACATCAAGTAAAAATTATCATTTCAGACA
AACAATATGTATAAAAAAATCATTCGACTAA

Domains

Predicted by InterProScan.

GHKL domain (HATPase_c_5)

(331-431)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD/comD1 Streptococcus equinus JB1

74.569

53.211

0.397

Multiple sequence alignment