Detailed information NTG0033549

Bioinformatically predicted

Overview

• Name: comX/sigX/comX2/sigX2
• Type: Regulator
• Locus tag: SEQ_RS09565
• Genome accession: NC_012471
• Coordinates: 1964317..1964802 (-)
• Length: 161 a.a.
• NCBI ID: WP_012680087.1
• Uniprot ID: C0M8B7
• Organism: Streptococcus equi subsp. equi 4047
• Function: activate transcription of late competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1959317..1969802

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SEQ_RS09540 (SEQ_1951)	-	1959748..1960308 (-)	561	WP_012680112.1	TIGR01440 family protein	-
SEQ_RS09545 (SEQ_1952)	-	1960321..1960794 (-)	474	WP_012680113.1	ECF transporter S component	-
SEQ_RS09550 (SEQ_1953)	-	1960800..1961549 (-)	750	WP_012680114.1	bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase	-
SEQ_RS09555 (SEQ_1954)	truA	1961539..1962288 (-)	750	WP_012680115.1	tRNA pseudouridine(38-40) synthase TruA	-
SEQ_RS09560 (SEQ_1955)	-	1962475..1963839 (+)	1365	WP_012680116.1	aspartate kinase	-
SEQ_RS09565 (SEQ_1956)	comX/sigX/comX2/sigX2	1964317..1964802 (-)	486	WP_012680087.1	hypothetical protein	Regulator

Sequence

Protein

• Length: 161 a.a.
• Molecular weight: 19345.31 Da
• Isoelectric Point: 7.3119

>NTDB_id=33549 SEQ_RS09565 WP_012680087.1 1964317..1964802(-) (comX/sigX/comX2/sigX2) [Streptococcus equi subsp. equi 4047]
MTDDLVRLFDKIKPIIMKLRQHYYIQLWELDDWLQEGRLILYRLLVTYPELIEDEEKLYRYFKTKFSSYLKDVLRQQESQ
KRRFHKMAYEEIGSVGHAIPAGGLGVDDYVAYQLIVKEVEERLTEGELSQFRALIRGERFEGRRALLRKIGPYFQDFTGE
K

Nucleotide

• Length: 486 bp

>NTDB_id=33549 SEQ_RS09565 WP_012680087.1 1964317..1964802(-) (comX/sigX/comX2/sigX2) [Streptococcus equi subsp. equi 4047]
ATGACTGATGATTTAGTGAGGTTGTTTGATAAGATCAAGCCTATTATTATGAAGCTAAGACAGCATTATTATATTCAGCT
GTGGGAGCTAGATGATTGGTTACAGGAGGGGCGGTTGATCTTGTATCGGTTATTGGTCACTTATCCAGAATTGATAGAGG
ATGAGGAGAAGCTATATCGTTATTTTAAGACCAAGTTTTCCTCTTATTTGAAGGACGTGTTGCGGCAGCAGGAGAGTCAG
AAGCGTCGGTTTCATAAGATGGCTTATGAGGAGATTGGGTCGGTAGGCCATGCGATACCAGCAGGTGGTTTGGGAGTAGA
TGATTATGTGGCTTATCAGTTGATTGTGAAGGAGGTTGAGGAGCGATTGACAGAGGGTGAGCTGTCGCAGTTTCGGGCTT
TGATCAGGGGAGAGCGGTTTGAGGGGAGACGGGCCTTGCTTCGCAAGATAGGACCTTACTTTCAGGACTTTACTGGTGAG
AAATAA

Domains

No domain identified.

3D structure

• AlphaFold DB: C0M8B7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS315	66.875	99.379	0.665
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS315	66.875	99.379	0.665
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS8232	66.875	99.379	0.665
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS8232	66.875	99.379	0.665
comX/sigX/comX2/sigX2	Streptococcus pyogenes JRS4	66.875	99.379	0.665
comX/sigX/comX1/sigX1	Streptococcus pyogenes JRS4	66.875	99.379	0.665
comX/sigX	Streptococcus infantarius subsp. infantarius ATCC BAA-102	47.097	96.273	0.453
comX/sigX	Streptococcus mutans UA159	45.86	97.516	0.447
comX	Streptococcus sobrinus strain NIDR 6715-7	45.752	95.031	0.435
comX/sigX/comX2/sigX2	Streptococcus mitis SK321	40.667	93.168	0.379
comR/comR1	Streptococcus gordonii str. Challis substr. CH1	40.397	93.789	0.379
comR/comR2	Streptococcus gordonii str. Challis substr. CH1	40.397	93.789	0.379
comX/sigX/comX1/sigX1	Streptococcus mitis SK321	39.333	93.168	0.366
comX/comX2	Streptococcus pneumoniae TIGR4	38.411	93.789	0.36
comX/comX1	Streptococcus pneumoniae TIGR4	38.411	93.789	0.36
comX/comX2	Streptococcus pneumoniae Rx1	38.411	93.789	0.36
comX/comX1	Streptococcus pneumoniae Rx1	38.411	93.789	0.36
comX/comX2	Streptococcus pneumoniae D39	38.411	93.789	0.36
comX/comX1	Streptococcus pneumoniae D39	38.411	93.789	0.36
comX/comX2	Streptococcus pneumoniae R6	38.411	93.789	0.36
comX/comX1	Streptococcus pneumoniae R6	38.411	93.789	0.36
comX/sigX/comX2/sigX2	Streptococcus mitis NCTC 12261	38.667	93.168	0.36