Detailed information NTG0334461

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: EQG65_RS13485
• Genome accession: NZ_CP035101
• Coordinates: 2650893..2651780 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain ATCC 12600
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2645893..2656780

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQG65_RS13450 (EQG65_13780)	-	2645912..2646004 (+)	93	WP_010956583.1	hypothetical protein	-
EQG65_RS13455 (EQG65_13785)	-	2646112..2646609 (-)	498	WP_001065268.1	glutathione peroxidase	-
EQG65_RS13460 (EQG65_13790)	-	2646619..2646879 (-)	261	WP_001789910.1	hypothetical protein	-
EQG65_RS13470 (EQG65_13800)	-	2647261..2647374 (-)	114	WP_011447078.1	hypothetical protein	-
EQG65_RS13475 (EQG65_13805)	-	2648033..2650033 (-)	2001	WP_000776751.1	ABC transporter permease	-
EQG65_RS13480 (EQG65_13810)	-	2650030..2650785 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
EQG65_RS13485 (EQG65_13815)	braS	2650893..2651780 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
EQG65_RS13490 (EQG65_13820)	braR	2651791..2652456 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
EQG65_RS13495 (EQG65_13825)	-	2652482..2652682 (-)	201	WP_000604728.1	hypothetical protein	-
EQG65_RS13500 (EQG65_13830)	-	2652880..2654304 (+)	1425	WP_000953744.1	alkaline phosphatase	-
EQG65_RS14335 (EQG65_13835)	-	2654364..2654465 (-)	102	WP_000731972.1	SE2200 family small protein	-
EQG65_RS13510 (EQG65_13840)	-	2654587..2655042 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
EQG65_RS13515 (EQG65_13845)	-	2655287..2656048 (-)	762	WP_000323455.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=334461 EQG65_RS13485 WP_000143419.1 2650893..2651780(-) (braS) [Staphylococcus aureus strain ATCC 12600]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=334461 EQG65_RS13485 WP_000143419.1 2650893..2651780(-) (braS) [Staphylococcus aureus strain ATCC 12600]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997