Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   EMO94_RS01235 Genome accession   NZ_CP035005
Coordinates   227741..228457 (-) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain PCFH-226     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 222741..233457
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EMO94_RS01220 - 223828..224778 (+) 951 WP_000790325.1 LacI family DNA-binding transcriptional regulator -
  EMO94_RS01225 - 224927..226411 (+) 1485 WP_000141407.1 sucrose-6-phosphate hydrolase -
  EMO94_RS01230 - 226408..227367 (+) 960 WP_001253294.1 carbohydrate kinase -
  EMO94_RS01235 agrA 227741..228457 (-) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  EMO94_RS01240 agrC 228476..229768 (-) 1293 WP_001825886.1 quorum-sensing sensor histidine kinase AgrC -
  EMO94_RS01245 agrD 229793..229933 (-) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  EMO94_RS01250 agrB 229930..230499 (-) 570 WP_001105708.1 accessory gene regulator AgrB -
  EMO94_RS14560 hld 230789..230869 (+) 81 WP_000046022.1 delta-hemolysin -
  EMO94_RS01260 - 231471..232256 (-) 786 WP_000867947.1 carbon-nitrogen family hydrolase -
  EMO94_RS01265 - 232564..233190 (-) 627 WP_000522384.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=333914 EMO94_RS01235 WP_000688492.1 227741..228457(-) (agrA) [Staphylococcus aureus strain PCFH-226]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=333914 EMO94_RS01235 WP_000688492.1 227741..228457(-) (agrA) [Staphylococcus aureus strain PCFH-226]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACGTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTAT
TATCAAAAGATAATAGCGTTGAAACGATTGAGTTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTCAGATGTCATAATAGCTTTGTCGTCAATCGTCATAATATCGAATCTATTG
ATTCGAAAGAGCGTATTGTTTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1

Multiple sequence alignment