Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   FWK58_RS03185 Genome accession   NZ_CP042991
Coordinates   681343..683172 (+) Length   609 a.a.
NCBI ID   WP_075293477.1    Uniprot ID   A0A9Q6YYL4
Organism   Histophilus somni strain UOC-KLM-ATR-012     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 676343..688172
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FWK58_RS03155 (FWK58_03155) - 677160..677510 (-) 351 WP_075293481.1 RidA family protein -
  FWK58_RS03160 (FWK58_03160) - 677621..678343 (+) 723 WP_075293480.1 YwiC-like family protein -
  FWK58_RS03165 (FWK58_03165) - 678358..679257 (+) 900 WP_012341793.1 RimK family alpha-L-glutamate ligase -
  FWK58_RS03170 (FWK58_03170) lpxK 679376..680371 (+) 996 WP_075293479.1 tetraacyldisaccharide 4'-kinase -
  FWK58_RS03175 (FWK58_03175) - 680368..680565 (+) 198 WP_011608813.1 Trm112 family protein -
  FWK58_RS03180 (FWK58_03180) kdsB 680580..681350 (+) 771 WP_075293478.1 3-deoxy-manno-octulosonate cytidylyltransferase -
  FWK58_RS03185 (FWK58_03185) uvrC 681343..683172 (+) 1830 WP_075293477.1 excinuclease ABC subunit UvrC Machinery gene
  FWK58_RS09905 (FWK58_03190) - 683238..683624 (-) 387 WP_075293476.1 TM2 domain-containing protein -
  FWK58_RS03195 (FWK58_03195) rnb 683749..685728 (-) 1980 WP_075293475.1 exoribonuclease II -
  FWK58_RS03200 (FWK58_03200) - 685793..686581 (-) 789 WP_011608818.1 enoyl-ACP reductase -
  FWK58_RS03205 (FWK58_03205) - 686672..687427 (-) 756 WP_041605273.1 Nif3-like dinuclear metal center hexameric protein -

Sequence

Protein


Download         Length: 609 a.a.        Molecular weight: 68999.11 Da        Isoelectric Point: 9.2705

>NTDB_id=333790 FWK58_RS03185 WP_075293477.1 681343..683172(+) (uvrC) [Histophilus somni strain UOC-KLM-ATR-012]
MFDAKNFLANVTHQPGVYRMFDEKGQVIYVGKAKDLKKRLSSYFRTNLNSKKTSALVSHIHSIETTITASETEALLLEHN
YIKAFQPRYNVLLRDDKSYPYILLTKERHPRITSHRGSKKVQGEYFGPYPHAGSVRETLSLLQKLFPIRQCENSVYNNRS
RPCLQYQIGRCSGPCIDGLVSDEEYQQQVDFARLFLQGKDQQVLEHLIKKMEQASMQLNFEQAAYFRDQIQAIRAVIEKQ
FVSNERLDDMDIMAIAYQLGIACVQVLFIRQGKVLGNRSYFPKVPANTDLSELTETFVGQFYLQGHQGRIIPSTIIVDHV
LNEKHELEVLLTEQAGRKVNIQDNVKGNKSKFLHLAQMNAQAALVTQLKQANLIQERYQALQELLSLTTIKRMECFDISH
TMGEQTIASCVVFDTEGPLKSDYRRFNISGITAGDDYAAMEQALLKRYDRPLENEKIPDIIFIDGGKGQLNRALQVFAQL
NVSWDKNKPLLIGVAKGVDRKAGLETLIISKQNKEVNLLPDSLALHLIQHIRDESHHHAIGGHRKKRQQAFTQSGLEAIE
GVGAKRRQALLKYLGGMQGVKNATLAEISSVPGISAALAERIYETLRSE

Nucleotide


Download         Length: 1830 bp        

>NTDB_id=333790 FWK58_RS03185 WP_075293477.1 681343..683172(+) (uvrC) [Histophilus somni strain UOC-KLM-ATR-012]
ATGTTTGATGCCAAAAACTTTCTTGCCAATGTAACGCACCAGCCCGGTGTATACCGAATGTTTGATGAAAAAGGGCAGGT
GATTTATGTTGGTAAGGCAAAAGATTTGAAAAAGCGTTTATCCAGCTATTTTCGCACTAATTTGAACAGTAAAAAAACTT
CCGCACTGGTTTCGCATATTCATTCAATAGAAACAACAATCACCGCTTCAGAAACTGAAGCATTATTGCTTGAACATAAT
TATATTAAAGCTTTTCAGCCCCGTTACAATGTTTTATTACGTGATGATAAATCCTATCCCTATATTCTATTAACGAAAGA
ACGTCATCCTAGAATTACCTCGCATCGAGGTTCAAAAAAAGTACAAGGTGAGTATTTTGGCCCTTATCCCCATGCAGGAT
CGGTACGTGAAACTCTCTCTTTGTTGCAAAAATTATTTCCTATTCGGCAATGTGAAAACTCGGTATATAACAACCGCTCT
CGCCCTTGTTTGCAGTATCAAATCGGGCGTTGCAGTGGCCCTTGTATTGATGGTTTAGTATCTGATGAAGAATATCAGCA
ACAGGTCGATTTTGCTCGGCTATTTTTACAAGGTAAAGATCAGCAAGTGTTGGAGCATTTGATCAAAAAAATGGAACAAG
CGAGTATGCAACTTAATTTTGAGCAGGCAGCTTATTTCCGTGATCAAATTCAGGCGATTCGTGCGGTAATTGAAAAACAA
TTTGTTTCTAACGAACGTTTAGATGATATGGATATTATGGCAATTGCTTATCAGCTTGGTATTGCTTGTGTACAAGTTTT
ATTTATTCGTCAGGGAAAAGTATTAGGTAATCGCAGTTATTTTCCCAAAGTGCCGGCAAATACGGATTTAAGTGAATTAA
CCGAAACGTTTGTCGGACAGTTTTATTTACAGGGGCATCAAGGTCGGATTATACCAAGTACCATTATTGTTGATCATGTT
TTGAATGAAAAACATGAACTTGAGGTTTTATTAACAGAACAAGCCGGACGTAAAGTAAATATTCAAGATAATGTGAAAGG
CAATAAAAGCAAATTTTTACATCTGGCTCAAATGAATGCACAAGCCGCATTAGTAACACAGCTTAAACAAGCTAATTTAA
TACAAGAGCGTTATCAGGCATTACAAGAACTTTTGTCTTTAACTACCATTAAACGTATGGAATGTTTTGATATCAGTCAT
ACTATGGGAGAGCAAACAATAGCTTCTTGCGTTGTTTTTGATACTGAAGGACCGTTGAAATCAGATTATCGTCGTTTCAA
CATAAGCGGAATTACTGCAGGCGATGATTATGCCGCTATGGAGCAGGCTTTGTTGAAACGTTATGATCGCCCATTAGAAA
ATGAGAAAATTCCAGATATTATTTTTATTGATGGGGGAAAGGGGCAATTAAACCGTGCTTTACAAGTTTTTGCACAATTA
AATGTCTCTTGGGATAAAAATAAACCGCTCTTAATTGGGGTAGCAAAAGGGGTAGATCGTAAAGCAGGTTTAGAGACGTT
AATTATTAGTAAACAAAATAAGGAAGTGAATTTACTGCCTGACAGCCTTGCCCTTCATCTTATTCAACATATTCGTGATG
AAAGTCATCATCATGCCATTGGCGGTCATCGTAAAAAACGTCAACAGGCTTTTACTCAAAGCGGTCTAGAAGCCATTGAA
GGTGTTGGAGCAAAACGAAGACAAGCTTTATTAAAATATTTAGGGGGCATGCAAGGTGTAAAAAATGCGACTTTAGCAGA
AATTTCCTCCGTTCCGGGCATTTCTGCTGCGTTGGCGGAACGGATTTATGAAACGCTAAGAAGTGAATAA

Domains

Predicted by InterProScan.

Helix-hairpin-helix domain (HHH_5)

(556-607)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(382-540)

UvrB/uvrC motif (UVR)

(202-235)

GIY-YIG catalytic domain (GIY-YIG)

(15-90)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A9Q6YYL4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

36.364

99.343

0.361