Detailed information NTG0033333

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: SP70585_RS10130
• Genome accession: NC_012468
• Coordinates: 1879588..1880625 (-)
• Length: 345 a.a.
• NCBI ID: WP_012677144.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae 70585
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1874588..1885625

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SP70585_RS10105 (SP70585_2035)	-	1875389..1876720 (-)	1332	WP_000390048.1	hemolysin family protein	-
SP70585_RS10110 (SP70585_2036)	endA	1876949..1877773 (-)	825	WP_001036779.1	DNA-entry nuclease EndA	Machinery gene
SP70585_RS10115 (SP70585_2037)	-	1877812..1878000 (-)	189	WP_001813390.1	DNA-directed RNA polymerase subunit beta	-
SP70585_RS10120 (SP70585_2038)	murA	1877993..1879276 (-)	1284	WP_000358028.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
SP70585_RS10125	-	1879300..1879530 (-)	231	WP_000250392.1	DUF1146 family protein	-
SP70585_RS10130 (SP70585_2040)	sepM	1879588..1880625 (-)	1038	WP_012677144.1	SepM family pheromone-processing serine protease	Regulator
SP70585_RS10135 (SP70585_2041)	coaD	1880609..1881097 (-)	489	WP_001280753.1	pantetheine-phosphate adenylyltransferase	-
SP70585_RS10140 (SP70585_2042)	rsmD	1881087..1881626 (-)	540	WP_001819515.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
SP70585_RS10145 (SP70585_2043)	asnA	1881691..1882683 (-)	993	WP_000747993.1	aspartate--ammonia ligase	-
SP70585_RS10155 (SP70585_2044)	-	1882795..1883478 (-)	684	WP_001016917.1	Bax inhibitor-1/YccA family protein	-
SP70585_RS10160 (SP70585_2045)	-	1883534..1884274 (-)	741	WP_000152678.1	RNA methyltransferase	-
SP70585_RS10165 (SP70585_2046)	-	1884308..1884586 (+)	279	WP_001174613.1	acylphosphatase	-
SP70585_RS10170 (SP70585_2047)	yidC	1884664..1885590 (+)	927	WP_000835955.1	membrane protein insertase YidC	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37549.57 Da
• Isoelectric Point: 5.0724

>NTDB_id=33333 SP70585_RS10130 WP_012677144.1 1879588..1880625(-) (sepM) [Streptococcus pneumoniae 70585]
MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLKVNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFT
DIRSAQETTGGSSDVEFLRINQFYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVISNVPISFSTAGIGGPSAGLMFSL
AIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGIDKKVVASARAGAAIFFTPDNPVSEEEQKAHPDAKNNYQTALEAAK
TIKTDMKIVPVKTLQDAIDYLKNNP

Nucleotide

• Length: 1038 bp

>NTDB_id=33333 SP70585_RS10130 WP_012677144.1 1879588..1880625(-) (sepM) [Streptococcus pneumoniae 70585]
ATGAAAAAAAAGATTAGATGGCCCTTATACGTCATTGCGGCCTTGATTGTGACTTTCTTGGCATTTGTAGTGCCCTTGCC
TTATTATATAGAGGTTCCAGGTGGTTCGGAAGATATTCGCCAAGTCCTTAAAGTAAATGACACAGAAGATAAGGAAGCTG
GTGCCTATCAATTCGTTACGGTTGGTGTTCAACATGCCACTTTAGCTCATATGATTTATGCTTGGTTGACACCTTTTACA
GATATTCGTAGTGCTCAGGAGACTACAGGTGGTTCTTCCGATGTTGAATTTCTGCGAATCAATCAATTCTACATGCAAAC
ATCGCAAAATATGGCCAAGTATCAAGGACTAAAAACAGCTGGTAAGGATATCGAACTCAAGTACTTTGGAGTTTATGTTT
TGAATGTGACGGATAATTCAACCTTTAAAGGGATTCTCAATATCTCTGATACAGTCACAGCAGTCAATGATCAGACCTTT
GATAGTTCCAAAGACTTGATTGATTACGTCAGTTCTCAAAAATTAGGGGATTCCGTCAAGGTCACCTATGAAGAGGATGG
GCAAACCAAGTCTGCAGAAGGAAAGATTATCACCTTGGAAAATGGCAAAAATGGAATTGGAATCGGCTTGATTGACCGTA
CAGAGGTAATCAGCAATGTCCCAATTAGCTTTTCAACAGCTGGTATTGGCGGCCCAAGTGCTGGTCTCATGTTTAGTCTA
GCTATCTATACTCAAATAGCTCACCCAGATCTTCGTAATGGTCGTATTGTTGCCGGTACAGGTACCATTGACCGCGATGG
TAATGTGGGAGACATTGGAGGTATTGATAAGAAGGTTGTAGCTTCGGCTAGGGCAGGTGCTGCTATTTTCTTTACTCCTG
ATAACCCTGTTAGCGAAGAAGAACAAAAGGCGCATCCGGACGCGAAAAACAACTACCAAACAGCCCTAGAAGCGGCTAAA
ACAATCAAGACGGATATGAAAATCGTGCCCGTTAAAACCCTACAAGATGCGATTGATTACTTGAAAAACAATCCCTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (130-193)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (230-296)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	59.357	99.13	0.588