Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrA   Type   Machinery gene
Locus tag   CA897_RS21655 Genome accession   NZ_CP042899
Coordinates   4532004..4534826 (+) Length   940 a.a.
NCBI ID   WP_000357740.1    Uniprot ID   Q3YUS6
Organism   Escherichia coli strain CFSAN061763     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 4527004..4539826
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CA897_RS21630 (CA897_021895) soxR 4527941..4528405 (-) 465 WP_000412424.1 redox-sensitive transcriptional activator SoxR -
  CA897_RS21635 (CA897_021900) soxS 4528491..4528814 (+) 324 WP_000019358.1 superoxide response transcriptional regulator SoxS -
  CA897_RS21640 (CA897_021905) pdeC 4528817..4530403 (-) 1587 WP_001550430.1 c-di-GMP phosphodiesterase PdeC -
  CA897_RS21645 (CA897_021910) yjcB 4530833..4531114 (+) 282 WP_001295689.1 YjcB family protein -
  CA897_RS21650 (CA897_021915) ssb 4531213..4531749 (-) 537 WP_000168305.1 single-stranded DNA-binding protein SSB1 Machinery gene
  CA897_RS21655 (CA897_021920) uvrA 4532004..4534826 (+) 2823 WP_000357740.1 excinuclease ABC subunit UvrA Machinery gene
  CA897_RS21660 (CA897_021925) yjbR 4534861..4535217 (-) 357 WP_000155657.1 MmcQ/YjbR family DNA-binding protein -
  CA897_RS21665 (CA897_021930) yjbQ 4535221..4535637 (-) 417 WP_000270375.1 secondary thiamine-phosphate synthase enzyme YjbQ -
  CA897_RS21670 (CA897_021935) aphA 4535748..4536461 (-) 714 WP_001226928.1 acid phosphatase AphA -
  CA897_RS21675 (CA897_021940) - 4536862..4537224 (+) 363 Protein_4278 hypothetical protein -
  CA897_RS21680 (CA897_021945) tyrB 4537587..4538780 (-) 1194 WP_001550428.1 aromatic amino acid transaminase -

Sequence

Protein


Download         Length: 940 a.a.        Molecular weight: 103867.54 Da        Isoelectric Point: 6.6066

>NTDB_id=332838 CA897_RS21655 WP_000357740.1 4532004..4534826(+) (uvrA) [Escherichia coli strain CFSAN061763]
MDKIEVRGARTHNLKNINLVIPRDKLIVVTGLSGSGKSSLAFDTLYAEGQRRYVESLSAYARQFLSLMEKPDVDHIEGLS
PAISIEQKSTSHNPRSTVGTITEIHDYLRLLFARVGEPRCPDHDVPLAAQTVSQMVDNVLSQPEGKRLMLLAPIIKERKG
EHTKTLENLASQGYIRARIDGEVCDLSDPPKLELQKKHTIEVVVDRFKVRDDLTQRLAESFETALELSGGTAVVADMDDP
KAEELLFSANFACPICGYSMRELEPRLFSFNNPAGACPTCDGLGVQQYFDPDRVIQNPELSLAGGAIRGWDRRNFYYFQM
LKSLADHYKFDVEAPWGSLSANVHKVVLYGSGKENIEFKYMNDRGDTSIRRHPFEGVLHNMERRYKETESSAVREELAKF
ISNRPCASCEGTRLRREARHVYVENTPLPAISDMSIGHAMEFFNNLKLAGQRAKIAEKILKEIGDRLKFLVNVGLNYLTL
SRSAETLSGGEAQRIRLASQIGAGLVGVMYVLDEPSIGLHQRDNERLLGTLIHLRDLGNTVIVVEHDEDAIRAADHVIDI
GPGAGVHGGEVVAEGPLEAIMAVPESLTGQYMSGKRKIEVPKKRVPANPEKVLKLTGARGNNLKDVTLTLPVGLFTCITG
VSGSGKSTLINDTLFPIAQRQLNGATIAEPAPYRDIQGLEHFDKVIDIDQSPIGRTPRSNPATYTGVFTPVRELFAGVPE
SRARGYTPGRFSFNVRGGRCEACQGDGVIKVEMHFLPDIYVPCDQCKGKRYNRETLEIKYKGKTIHEVLDMTIEEAREFF
DAVPALARKLQTLMDVGLTYIRLGQSATTLSGGEAQRVKLARELSKRGTGQTLYILDEPTTGLHFADIQQLLDVLHKLRD
QGNTIVVIEHNLDVIKTADWIVDLGPEGGSGGGEILVSGTPETVAECEASHTARFLKPML

Nucleotide


Download         Length: 2823 bp        

>NTDB_id=332838 CA897_RS21655 WP_000357740.1 4532004..4534826(+) (uvrA) [Escherichia coli strain CFSAN061763]
ATGGATAAGATCGAAGTTCGGGGCGCCCGCACCCATAATCTCAAAAACATCAACCTCGTTATCCCCCGCGACAAACTTAT
TGTCGTGACCGGGCTTTCGGGTTCTGGCAAATCCTCGCTCGCTTTCGACACCTTATATGCCGAAGGGCAGCGCCGTTACG
TTGAATCCCTTTCCGCCTACGCGCGGCAGTTTCTGTCACTGATGGAAAAGCCGGACGTCGATCATATTGAGGGGCTTTCT
CCTGCCATCTCAATTGAGCAGAAATCGACGTCTCATAACCCGCGTTCTACGGTGGGGACAATCACCGAAATCCACGACTA
TTTGCGTTTGTTGTTCGCCCGCGTCGGTGAGCCGCGCTGCCCGGACCACGATGTACCGCTGGCGGCGCAAACCGTCAGTC
AGATGGTGGATAACGTGTTGTCCCAGCCGGAAGGTAAACGCCTGATGCTGCTCGCACCAATCATTAAAGAGCGCAAAGGC
GAACACACCAAAACGCTGGAAAATCTGGCAAGCCAGGGTTACATCCGTGCTCGTATTGATGGCGAAGTCTGCGATCTTTC
CGATCCGCCGAAACTGGAACTGCAAAAGAAACATACCATTGAAGTGGTGGTTGATCGCTTCAAGGTGCGTGACGATCTCA
CCCAACGTCTGGCAGAGTCGTTTGAAACCGCGCTGGAGCTTTCCGGTGGTACCGCGGTAGTTGCCGATATGGACGATCCA
AAAGCGGAAGAGCTGCTATTTTCCGCCAACTTCGCCTGCCCAATTTGCGGCTATAGTATGCGTGAACTGGAACCACGCCT
GTTTTCGTTTAACAACCCGGCGGGGGCCTGCCCAACCTGTGACGGCCTTGGCGTGCAGCAATATTTCGATCCTGACCGCG
TGATCCAGAATCCGGAACTGTCGCTGGCTGGCGGTGCGATCCGAGGCTGGGATCGCCGCAACTTCTATTACTTCCAGATG
CTGAAATCGCTGGCAGATCACTATAAGTTCGACGTCGAAGCGCCGTGGGGCAGCCTGAGCGCGAACGTGCATAAAGTGGT
GTTGTACGGTTCTGGCAAAGAAAACATTGAATTCAAATACATGAACGATCGTGGCGATACCTCCATTCGTCGTCATCCGT
TCGAAGGCGTGCTGCACAATATGGAGCGCCGTTATAAAGAGACGGAATCCAGTGCGGTACGTGAAGAATTAGCCAAGTTT
ATCAGCAATCGCCCGTGCGCCAGCTGCGAAGGAACCCGTCTGCGTCGGGAAGCGCGCCATGTGTATGTCGAGAATACGCC
GCTGCCTGCTATCTCCGACATGAGCATCGGTCATGCGATGGAATTCTTCAACAATCTCAAACTCGCAGGTCAGCGAGCGA
AGATTGCGGAAAAAATTCTTAAAGAGATTGGCGATCGCCTGAAATTCCTCGTTAACGTCGGCCTGAATTACCTGACACTT
TCCCGCTCGGCAGAGACACTTTCTGGCGGTGAAGCCCAGCGTATCCGTCTGGCGAGCCAGATTGGTGCGGGCCTGGTTGG
CGTTATGTACGTGCTCGATGAGCCGTCTATCGGCCTGCACCAGCGCGATAACGAGCGCCTGTTGGGTACGCTTATCCATC
TGCGCGATCTCGGTAATACCGTGATTGTGGTGGAGCACGACGAAGACGCGATTCGCGCCGCTGACCATGTGATCGACATT
GGTCCTGGTGCGGGTGTTCACGGCGGTGAAGTGGTCGCGGAAGGTCCACTGGAAGCGATTATGGCGGTGCCGGAGTCGTT
GACCGGGCAGTACATGAGCGGTAAACGCAAGATTGAAGTGCCGAAGAAACGCGTTCCGGCGAATCCGGAAAAAGTGCTGA
AGCTGACAGGCGCACGCGGTAATAACCTGAAAGACGTGACGCTGACGCTGCCAGTCGGTCTGTTTACCTGCATCACAGGG
GTTTCAGGTTCCGGTAAATCGACACTGATTAACGACACACTGTTCCCGATTGCCCAACGCCAGTTGAATGGGGCGACCAT
CGCCGAACCGGCACCGTATCGCGATATTCAGGGACTGGAGCATTTCGATAAAGTGATCGATATCGACCAAAGCCCAATTG
GTCGTACTCCGCGTTCTAACCCGGCGACCTATACCGGCGTGTTTACACCTGTGCGCGAACTGTTTGCGGGCGTACCGGAA
TCCCGTGCGCGCGGCTATACGCCGGGACGTTTCAGCTTTAACGTCCGTGGCGGGCGCTGCGAAGCCTGTCAGGGCGATGG
CGTGATCAAAGTGGAGATGCACTTCCTGCCGGATATCTACGTGCCGTGCGACCAGTGCAAAGGTAAACGCTATAACCGCG
AAACGCTGGAAATTAAGTACAAAGGCAAAACCATCCACGAAGTGCTGGATATGACCATCGAAGAGGCGCGTGAGTTCTTT
GATGCGGTGCCAGCTCTGGCGCGTAAGCTGCAAACGTTGATGGACGTTGGCCTGACGTACATTCGCCTCGGGCAGTCCGC
AACCACGCTTTCTGGTGGTGAAGCCCAGCGCGTGAAGCTGGCGCGTGAGCTGTCAAAACGCGGCACCGGGCAGACGCTGT
ATATTCTTGATGAGCCGACCACCGGTCTGCACTTCGCCGATATTCAGCAACTGCTCGACGTACTGCATAAACTGCGCGAT
CAGGGCAACACCATTGTGGTGATTGAGCACAATCTCGACGTGATCAAAACCGCTGACTGGATTGTCGACCTGGGACCAGA
AGGCGGCAGTGGCGGCGGCGAAATCCTCGTCTCCGGTACGCCAGAAACCGTCGCGGAGTGCGAAGCTTCGCATACGGCAC
GCTTCCTCAAGCCGATGCTGTAA

Domains

Predicted by InterProScan.

UvrA DNA-binding domain (UvrA_DNA-bind)

(290-399)

ABC transporter (ABC_tran)

(806-860)

UvrA interaction domain (UvrA_inter)

(130-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3YUS6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrA Streptococcus pneumoniae R6

57.37

100

0.576
  uvrA Streptococcus pneumoniae TIGR4

57.37

100

0.576
  uvrA Streptococcus pneumoniae D39

57.37

100

0.576

Multiple sequence alignment