Detailed information NTG0033256

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: SPP_RS09800
• Genome accession: NC_012467
• Coordinates: 1829638..1830675 (-)
• Length: 345 a.a.
• NCBI ID: WP_000727276.1
• Uniprot ID: A0AAQ2ZXI6
• Organism: Streptococcus pneumoniae P1031
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1824638..1835675

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SPP_RS09780 (SPP_1983)	-	1825377..1826708 (-)	1332	WP_000390039.1	hemolysin family protein	-
SPP_RS09785 (SPP_1984)	endA	1826999..1827823 (-)	825	WP_001036786.1	DNA-entry nuclease EndA	Machinery gene
SPP_RS09790 (SPP_1985)	-	1827862..1828050 (-)	189	WP_001813390.1	DNA-directed RNA polymerase subunit beta	-
SPP_RS09795 (SPP_1986)	murA	1828043..1829326 (-)	1284	WP_000358028.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
SPP_RS12380	-	1829350..1829580 (-)	231	WP_000250392.1	DUF1146 family protein	-
SPP_RS09800 (SPP_1988)	sepM	1829638..1830675 (-)	1038	WP_000727276.1	SepM family pheromone-processing serine protease	Regulator
SPP_RS09805 (SPP_1989)	coaD	1830659..1831147 (-)	489	WP_001280742.1	pantetheine-phosphate adenylyltransferase	-
SPP_RS09810 (SPP_1990)	rsmD	1831137..1831676 (-)	540	WP_000706962.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
SPP_RS09815 (SPP_1991)	asnA	1831741..1832733 (-)	993	WP_000747993.1	aspartate--ammonia ligase	-
SPP_RS09820 (SPP_1993)	-	1832844..1833527 (-)	684	WP_001016917.1	Bax inhibitor-1/YccA family protein	-
SPP_RS09825 (SPP_1994)	-	1833583..1834323 (-)	741	WP_000152700.1	RNA methyltransferase	-
SPP_RS09830 (SPP_1995)	-	1834357..1834635 (+)	279	WP_001174613.1	acylphosphatase	-
SPP_RS09835 (SPP_1996)	yidC	1834713..1835639 (+)	927	WP_000835941.1	membrane protein insertase YidC	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37553.61 Da
• Isoelectric Point: 5.0724

>NTDB_id=33256 SPP_RS09800 WP_000727276.1 1829638..1830675(-) (sepM) [Streptococcus pneumoniae P1031]
MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLKVNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFT
DIRSAQETTGGSSDVEFMRINQFYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVISNVPISFSTAGIGGPSAGLMFSL
AIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGIDKKVVASARAGAAIFFAPDNPVSEEEQKAHLDAKNNYQTALEAAK
TIKTDMKIVPVKTLQDAIDYLKNNP

Nucleotide

• Length: 1038 bp

>NTDB_id=33256 SPP_RS09800 WP_000727276.1 1829638..1830675(-) (sepM) [Streptococcus pneumoniae P1031]
ATGAAAAAAAAGATTAGATGGCCCTTATACGTCATTGCGGCCTTGATTGTGACTTTCTTGGCATTTGTAGTGCCCTTGCC
TTATTATATAGAGGTTCCAGGTGGTTCGGAAGATATTCGCCAAGTCCTTAAAGTAAATGACACAGAAGATAAGGAAGCTG
GTGCCTATCAATTCGTTACGGTTGGTGTTCAACATGCCACTTTAGCTCATATGATTTATGCTTGGTTGACACCTTTTACA
GATATTCGTAGTGCTCAGGAGACTACAGGTGGTTCTTCCGATGTTGAATTTATGCGAATCAATCAATTCTACATGCAAAC
ATCGCAAAATATGGCCAAGTATCAAGGACTAAAAACAGCTGGTAAGGATATCGAACTCAAGTACTTTGGAGTTTATGTTT
TGAATGTGACGGATAATTCAACCTTTAAAGGGATTCTCAATATCTCTGATACAGTCACAGCAGTCAATGATCAGACCTTT
GATAGTTCCAAAGACTTGATTGATTACGTCAGTTCTCAAAAATTAGGGGATTCCGTCAAGGTCACCTATGAAGAGGATGG
GCAAACCAAGTCTGCAGAAGGAAAGATTATCACCTTGGAAAATGGCAAAAATGGAATTGGAATCGGCTTGATTGACCGTA
CAGAGGTAATCAGCAATGTCCCAATTAGCTTTTCAACAGCTGGTATTGGCGGCCCAAGTGCTGGTCTCATGTTTAGTCTA
GCTATCTATACTCAAATAGCTCACCCAGATCTTCGTAATGGTCGTATTGTTGCCGGTACAGGTACCATTGACCGCGATGG
TAATGTGGGAGACATTGGAGGTATTGATAAGAAGGTTGTAGCTTCGGCTAGGGCAGGTGCTGCTATTTTCTTTGCTCCTG
ATAACCCTGTTAGCGAAGAAGAACAAAAGGCGCATCTGGACGCGAAAAACAACTACCAAACAGCCCTAGAAGCGGCTAAA
ACAATCAAGACGGATATGAAAATCGTGCCCGTTAAAACCCTACAAGATGCGATTGATTACTTGAAAAACAATCCCTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (130-193)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (230-296)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	59.357	99.13	0.588