Detailed information    

insolico Bioinformatically predicted

Overview

Name   cclA/cilC   Type   Machinery gene
Locus tag   SPP_RS08950 Genome accession   NC_012467
Coordinates   1683734..1684393 (+) Length   219 a.a.
NCBI ID   WP_000565003.1    Uniprot ID   A0A0E9GWM6
Organism   Streptococcus pneumoniae P1031     
Function   processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1678734..1689393
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPP_RS08925 (SPP_1810) - 1679039..1679356 (-) 318 WP_001151646.1 PTS sugar transporter subunit IIB -
  SPP_RS08930 (SPP_1811) - 1679371..1680267 (-) 897 WP_000825669.1 PEP phosphonomutase -
  SPP_RS08935 (SPP_1812) - 1680270..1681532 (-) 1263 WP_000413339.1 PTS sugar transporter subunit IIC -
  SPP_RS08940 (SPP_1813) - 1681812..1682990 (+) 1179 WP_000175876.1 ROK family transcriptional regulator -
  SPP_RS08945 (SPP_1814) - 1683218..1683664 (-) 447 WP_000155414.1 GNAT family N-acetyltransferase -
  SPP_RS08950 (SPP_1815) cclA/cilC 1683734..1684393 (+) 660 WP_000565003.1 A24 family peptidase Machinery gene
  SPP_RS08955 (SPP_1816) - 1684445..1685596 (-) 1152 WP_000481750.1 ImmA/IrrE family metallo-endopeptidase -
  SPP_RS08960 (SPP_1817) - 1685611..1686342 (-) 732 Protein_1725 hypothetical protein -
  SPP_RS12290 - 1686562..1686672 (+) 111 Protein_1726 prepilin peptidase -
  SPP_RS08965 (SPP_1819) trpA 1686644..1687420 (-) 777 WP_001126994.1 tryptophan synthase subunit alpha -
  SPP_RS08970 (SPP_1820) trpB 1687413..1688636 (-) 1224 WP_000331296.1 tryptophan synthase subunit beta -
  SPP_RS08975 (SPP_1821) - 1688614..1689213 (-) 600 WP_000169909.1 phosphoribosylanthranilate isomerase -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24841.94 Da        Isoelectric Point: 7.6166

>NTDB_id=33243 SPP_RS08950 WP_000565003.1 1683734..1684393(+) (cclA/cilC) [Streptococcus pneumoniae P1031]
MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTPLRPLDLIPILSQVFNRFRCRYCKVRYPVWYALFELGLG
LLFLLYSWELLSLGQVVLITAGLTLSIYDFRHQEYPLLVWMTFHLILIASSGWNLVMVSFLALGILAHFIDIRMGAGDFL
FLASCALVFSITELLILIQFASATGILAFLLQKKKERLPFVPFLLLATCLIIFGKLLLV

Nucleotide


Download         Length: 660 bp        

>NTDB_id=33243 SPP_RS08950 WP_000565003.1 1683734..1684393(+) (cclA/cilC) [Streptococcus pneumoniae P1031]
ATGATTGATTTTTATTTTTTTCTCGTCGGGAGCATTCTCGCTTCCTTTCTTGGTTTGGTCATTGACCGTTTTCCAGAGCA
ATCCATTATCAGTTCAGCCAGTCACTGCGATTCCTGTCAGACTCCCTTGCGTCCCTTAGATTTGATTCCGATTCTCTCAC
AGGTCTTCAATCGCTTTCGCTGTCGCTACTGCAAGGTCCGCTATCCTGTCTGGTATGCCCTCTTTGAACTAGGCTTAGGA
CTCCTCTTTCTGCTTTACTCTTGGGAATTGCTTTCCTTGGGGCAAGTCGTCCTAATCACCGCTGGTTTGACCTTGAGCAT
CTATGACTTTCGCCATCAGGAATATCCCTTACTGGTCTGGATGACTTTCCACCTAATCCTAATAGCTTCCTCTGGCTGGA
ATCTGGTCATGGTCTCCTTCCTTGCTCTTGGAATTTTGGCTCATTTTATCGATATCCGCATGGGCGCAGGGGATTTCCTC
TTTTTAGCTTCTTGTGCTCTCGTCTTTAGCATAACGGAGTTACTGATCTTGATTCAGTTTGCTTCTGCGACGGGTATCCT
AGCCTTTCTCCTGCAAAAGAAAAAGGAAAGACTTCCTTTCGTGCCTTTCCTCTTACTTGCTACTTGTTTGATTATTTTTG
GTAAGCTACTGCTTGTTTGA

Domains

Predicted by InterproScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(8-89)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0E9GWM6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cclA/cilC Streptococcus pneumoniae TIGR4

96.347

100

0.963
  cclA/cilC Streptococcus pneumoniae Rx1

95.89

100

0.959
  cclA/cilC Streptococcus pneumoniae D39

95.89

100

0.959
  cclA/cilC Streptococcus pneumoniae R6

95.89

100

0.959
  cclA/cilC Streptococcus mitis SK321

92.694

100

0.927
  cclA/cilC Streptococcus mitis NCTC 12261

86.758

100

0.868

Multiple sequence alignment