Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   FVE22_RS13245 Genome accession   NZ_CP042844
Coordinates   2698535..2699191 (-) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain JME66     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2693535..2704191
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FVE22_RS13215 yecA 2694786..2695451 (-) 666 WP_000847902.1 UPF0149 family protein YecA -
  FVE22_RS13235 pgsA 2696101..2696649 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  FVE22_RS13240 uvrC 2696706..2698538 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  FVE22_RS13245 letA 2698535..2699191 (-) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  FVE22_RS23100 - 2699333..2699404 (+) 72 Protein_2592 transcriptional regulator -
  FVE22_RS13250 yecU 2699487..2699663 (+) 177 WP_000590347.1 protein YecU -
  FVE22_RS13255 yecF 2699650..2699874 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  FVE22_RS13260 sdiA 2699942..2700664 (-) 723 WP_001152715.1 transcriptional regulator SdiA -
  FVE22_RS13265 tcyN 2700894..2701646 (-) 753 WP_001272991.1 L-cystine ABC transporter ATP-binding protein TcyN -
  FVE22_RS13270 tcyL 2701643..2702311 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  FVE22_RS13275 dcyD 2702326..2703312 (-) 987 WP_001128215.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=332079 FVE22_RS13245 WP_000611335.1 2698535..2699191(-) (letA) [Escherichia coli strain JME66]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=332079 FVE22_RS13245 WP_000611335.1 2698535..2699191(-) (letA) [Escherichia coli strain JME66]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486

Multiple sequence alignment