Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD/comD2   Type   Regulator
Locus tag   EHW89_RS09330 Genome accession   NZ_CP034543
Coordinates   1899135..1900457 (-) Length   440 a.a.
NCBI ID   WP_126468013.1    Uniprot ID   -
Organism   Streptococcus periodonticum strain KCOM 2412     
Function   phosphorylation of ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 1894135..1905457
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EHW89_RS09310 (EHW89_09310) - 1895462..1898038 (+) 2577 WP_126468009.1 YfhO family protein -
  EHW89_RS09325 (EHW89_09325) comE 1898386..1899135 (-) 750 WP_126468011.1 competence system response regulator transcription factor ComE Regulator
  EHW89_RS09330 (EHW89_09330) comD/comD2 1899135..1900457 (-) 1323 WP_126468013.1 sensor histidine kinase Regulator
  EHW89_RS09335 (EHW89_09335) - 1900472..1900621 (-) 150 WP_106388355.1 bacteriocin -
  EHW89_RS09345 (EHW89_09345) rlmH 1900903..1901382 (-) 480 WP_126468015.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  EHW89_RS09350 (EHW89_09350) htrA 1901575..1902765 (+) 1191 WP_003032033.1 S1C family serine protease Regulator
  EHW89_RS09355 (EHW89_09355) spo0J 1902820..1903587 (+) 768 WP_003032028.1 ParB/RepB/Spo0J family partition protein Regulator

Sequence

Protein


Download         Length: 440 a.a.        Molecular weight: 51742.49 Da        Isoelectric Point: 7.9865

>NTDB_id=331806 EHW89_RS09330 WP_126468013.1 1899135..1900457(-) (comD/comD2) [Streptococcus periodonticum strain KCOM 2412]
MNLDKILIIISFIIGILSFSIVHKKISKVKIIDFRFTLLCLCLFLFSSFINSINSLLAYLCLLLEPIIIYFYFYRFKKYE
KCISVFATFLIYSSVTTSEPFFSVIISSVTGDKFVDRYWGLFYIFINIISLIFILKAIDYFKFNFKYFKKADFKENILQL
NFYLLFIHFLLNLSHWLSNMKNLNSFSSMIATICFLMFMSTLFYLQSIREKYEKEEQIKQKEREQLQLQKYTDEIVSLYN
EIRGFRHDYGGMLASFQSAIHTGDIKEVERIYQEVLVNANLQLRSDKYTYFDLNNVGDSALRSVMTQTLFKTRDYNIELT
FEVKDFVKPLPIKLLDLVRMTSVLLNNAIEGAAESYQKTMNVSLVDLDTETILVIQNSRKKRPLDLEEIYQTDFSTKGEG
RGLGLSNIKEIINNYEGIILDTKIEDEYFTQVIRVRKEGL

Nucleotide


Download         Length: 1323 bp        

>NTDB_id=331806 EHW89_RS09330 WP_126468013.1 1899135..1900457(-) (comD/comD2) [Streptococcus periodonticum strain KCOM 2412]
ATGAATCTGGATAAAATACTTATAATCATTTCTTTTATTATCGGAATTTTATCTTTTTCAATTGTTCATAAAAAAATTAG
TAAAGTGAAAATTATAGATTTTCGCTTTACTTTATTGTGCTTGTGTTTATTTTTATTTTCATCTTTTATAAATTCGATTA
ATTCCTTATTAGCCTATTTATGTTTATTATTAGAGCCTATTATAATTTACTTCTATTTTTATCGCTTTAAGAAATATGAG
AAGTGTATATCAGTTTTTGCAACCTTTTTAATTTATTCATCTGTAACTACCTCTGAACCCTTCTTTTCAGTTATTATTTC
GTCTGTTACAGGTGATAAGTTTGTTGATAGATACTGGGGATTGTTCTATATTTTTATCAATATTATTTCTTTAATTTTTA
TTTTAAAAGCAATTGATTATTTTAAGTTTAATTTTAAATATTTTAAAAAGGCGGATTTCAAAGAGAATATTTTGCAGTTA
AACTTTTATCTCTTATTTATTCATTTTTTATTAAATTTATCGCATTGGCTTAGTAATATGAAAAATTTAAATAGTTTTTC
TAGTATGATTGCTACAATTTGCTTTTTAATGTTTATGTCAACTTTATTCTACTTACAATCTATTCGCGAAAAGTATGAAA
AAGAAGAACAAATTAAACAAAAAGAACGAGAACAACTACAATTACAAAAATATACAGATGAAATAGTGAGTCTGTATAAT
GAAATTCGAGGTTTTCGTCATGATTATGGAGGAATGTTGGCAAGCTTCCAATCAGCCATTCATACAGGAGATATAAAAGA
AGTAGAGCGAATTTATCAGGAAGTGCTAGTAAATGCTAATTTACAACTTCGTTCAGATAAATATACGTATTTTGATTTAA
ATAATGTTGGAGATTCAGCACTTAGAAGTGTTATGACACAAACCTTATTTAAGACGCGTGACTATAATATAGAATTAACA
TTTGAAGTAAAAGATTTTGTCAAACCCTTGCCGATTAAATTGTTAGATTTGGTTAGAATGACAAGCGTCCTTTTGAATAA
TGCCATAGAAGGAGCAGCAGAAAGTTATCAAAAAACGATGAATGTTTCTTTGGTGGATTTAGATACAGAAACAATCTTAG
TTATTCAAAATTCACGTAAGAAACGACCGCTAGATTTAGAAGAGATTTACCAAACTGATTTTTCAACAAAGGGTGAAGGA
CGTGGTTTAGGCTTAAGCAATATCAAAGAAATTATTAACAACTATGAAGGAATTATCCTCGATACTAAAATTGAGGATGA
ATATTTTACACAAGTAATAAGAGTAAGGAAAGAAGGTTTATAA

Domains

Predicted by InterproScan.

GHKL domain (HATPase_c_5)

(333-433)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD/comD2 Streptococcus gordonii strain NCTC7865

55.281

100

0.559
  comD/comD1 Streptococcus gordonii str. Challis substr. CH1

59.375

87.273

0.518
  comD Streptococcus mitis SK321

43.537

100

0.436
  comD/comD1 Streptococcus pneumoniae R6

43.649

98.409

0.43
  comD/comD1 Streptococcus pneumoniae Rx1

43.649

98.409

0.43
  comD/comD1 Streptococcus pneumoniae D39

43.649

98.409

0.43
  comD Streptococcus mitis NCTC 12261

47.453

84.773

0.402
  comD/comD2 Streptococcus pneumoniae TIGR4

47.185

84.773

0.4

Multiple sequence alignment